2004
Dietary Carotenoids and Risk of Lung Cancer in a Pooled Analysis of Seven Cohort Studies
Männistö S, Smith-Warner SA, Spiegelman D, Albanes D, Anderson K, van den Brandt PA, Cerhan JR, Colditz G, Feskanich D, Freudenheim JL, Giovannucci E, Goldbohm RA, Graham S, Miller AB, Rohan TE, Virtamo J, Willett WC, Hunter DJ. Dietary Carotenoids and Risk of Lung Cancer in a Pooled Analysis of Seven Cohort Studies. Cancer Epidemiology Biomarkers & Prevention 2004, 13: 40-48. PMID: 14744731, DOI: 10.1158/1055-9965.epi-038-3.Peer-Reviewed Original ResearchConceptsLung cancer riskCancer riskRelative riskCohort studyLung cancerRisk factorsIncident lung cancer casesBeta-cryptoxanthin intakeMultivariate relative riskBeta-carotene intakeStrong risk factorLung cancer casesPotential risk factorsLutein/zeaxanthinRandom-effects modelDietary questionnaireCurrent smokersMultivitamin useHistological typeIntervention trialsPooled analysisEpidemiological evidenceCancer casesCarotenoid intakeFood composition databases
1996
A methylenetetrahydrofolate reductase polymorphism and the risk of colorectal cancer.
Chen J, Giovannucci E, Kelsey K, Rimm EB, Stampfer MJ, Colditz GA, Spiegelman D, Willett WC, Hunter DJ. A methylenetetrahydrofolate reductase polymorphism and the risk of colorectal cancer. Cancer Research 1996, 56: 4862-4. PMID: 8895734.Peer-Reviewed Original ResearchConceptsVal/Val individualsVal/Val genotypeColorectal cancerOdds ratioVal genotypeHealth Professionals FollowColorectal cancer riskStrong risk factorHigh dietary intakeCase-control studyMore alcoholic drinksMethylenetetrahydrofolate reductase (MTHFR) polymorphismsVariant homozygous genotypeMethylenetetrahydrofolate reductase (MTHFR) geneProfessionals FollowAlcohol intakeInverse associationRisk factorsDietary intakeReduced incidenceMTHFR genotypeCancer riskBlood samplesAlcohol consumptionOncogenic alterations
1995
Body Size and Fat Distribution as Predictors of Coronary Heart Disease among Middle-aged and Older US Men
Rimm E, Stampfer M, Giovannucci E, Ascherio A, Spiegelman D, Colditz G, Willett W. Body Size and Fat Distribution as Predictors of Coronary Heart Disease among Middle-aged and Older US Men. American Journal Of Epidemiology 1995, 141: 1117-1127. PMID: 7771450, DOI: 10.1093/oxfordjournals.aje.a117385.Peer-Reviewed Original ResearchConceptsBody mass indexCoronary heart diseaseHeart diseaseFat distributionMass indexHip ratioProspective studyRisk factorsUS menAge-related hormonal changesIncident coronary heart diseaseLong-term prospective studiesCoronary risk factorsIncident coronary eventsStrong risk factorOlder US menRelative risk estimatesYears of ageCoronary eventsLean menCoronary diseaseObese menIndependent predictorsLong followRelative risk