2003
Multiple Sclerosis and Epstein-Barr Virus
Levin LI, Munger KL, Rubertone MV, Peck CA, Lennette ET, Spiegelman D, Ascherio A. Multiple Sclerosis and Epstein-Barr Virus. JAMA 2003, 289: 1533-1536. PMID: 12672770, DOI: 10.1001/jama.289.12.1533.Peer-Reviewed Original ResearchConceptsViral capsid antigenEpstein-Barr virusRisk of MSMultiple sclerosisRelative riskDevelopment of MSEBV viral capsid antigenOnset of MSCase-control studyDefense Serum RepositoryBlood sample collectionUS military personnelRace/ethnicityEBNA complexEBV antibodiesEBV infectionCytomegalovirus antibodiesSerum levelsCapsid antigenEarly antigenMS onsetAntibody titersIgG antibodiesPermanent disabilitySerum Repository
2000
Diarrhea and abnormalities of gastrointestinal function in a cohort of men and women with HIV infection
Knox T, Spiegelman D, Skinner S, Gorbach S. Diarrhea and abnormalities of gastrointestinal function in a cohort of men and women with HIV infection. The American Journal Of Gastroenterology 2000, 95: ajg20001597. PMID: 11151881, DOI: 10.1111/j.1572-0241.2000.03365.x.Peer-Reviewed Original ResearchConceptsIntravenous drug usersD-xylose absorptionLow D-xylose absorptionVitamin B12 levelsGastrointestinal functionHIV infectionLiver diseaseStool pathogensGastrointestinal dysfunctionB12 levelsLow serum vitamin B12 levelsLow vitamin B12 levelsSerum vitamin B12 levelsSeverity of immunosuppressionSudan III stainCells/mm3D-xylose testAbsence of diarrheaCohort of menAdvanced immunosuppressionCurrent diarrheaChronic diarrheaSerum levelsHIV treatmentFat diet
1999
Distribution of and Factors Associated With Serum Homocysteine Levels in Children: Child and Adolescent Trial for Cardiovascular Health
Osganian SK, Stampfer MJ, Spiegelman D, Rimm E, Cutler JA, Feldman HA, Montgomery DH, Webber LS, Lytle LA, Bausserman L, Nader PR. Distribution of and Factors Associated With Serum Homocysteine Levels in Children: Child and Adolescent Trial for Cardiovascular Health. JAMA 1999, 281: 1189-1196. PMID: 10199428, DOI: 10.1001/jama.281.13.1189.Peer-Reviewed Original ResearchConceptsSerum folic acidSystolic blood pressureHomocysteine levelsHomocysteine concentrationsCardiovascular diseaseSerum homocysteineAdolescent TrialBlood pressureSerum levelsFolic acidCardiovascular healthSerum total homocysteine concentrationsVitamin B12Mean homocysteine concentrationFuture cardiovascular diseaseVitamin B12 levelsSerum homocysteine concentrationsSchool-based cohortSerum homocysteine levelsTotal homocysteine concentrationsSerum lipid levelsBody mass indexCross-sectional analysisNonusers of multivitaminsB12 levels