2006
Alcohol intake and ovarian cancer risk: a pooled analysis of 10 cohort studies
Genkinger JM, Hunter DJ, Spiegelman D, Anderson KE, Buring JE, Freudenheim JL, Goldbohm RA, Harnack L, Hankinson SE, Larsson SC, Leitzmann M, McCullough ML, Marshall J, Miller AB, Rodriguez C, Rohan TE, Schatzkin A, Schouten LJ, Wolk A, Zhang SM, Smith-Warner SA. Alcohol intake and ovarian cancer risk: a pooled analysis of 10 cohort studies. British Journal Of Cancer 2006, 94: 757-762. PMID: 16495916, PMCID: PMC2361197, DOI: 10.1038/sj.bjc.6603020.Peer-Reviewed Original ResearchConceptsOvarian cancer riskCohort studyCancer riskPooled analysisAlcohol intakeRelative riskStudy-specific relative risksCox proportional hazards modelDepletion of folateModerate alcohol intakeOral contraceptive useProspective cohort studyHormone replacement therapyBody mass indexConfidence intervalsLevels of estrogenSerous ovarian cancerProportional hazards modelRandom-effects modelOvarian casesMenopausal statusMass indexReplacement therapyFolate intakeOvarian cancer
2000
Oral contraceptives and the incidence of multiple sclerosis
Hernán M, Hohol MJ, Olek MJ, Spiegelman D, Ascherio A. Oral contraceptives and the incidence of multiple sclerosis. Neurology 2000, 55: 848-853. PMID: 10994007, DOI: 10.1212/wnl.55.6.848.Peer-Reviewed Original ResearchConceptsRisk of MSHealth Study IIOral contraceptive useOral contraceptivesContraceptive useProtective effectHealth StudyNurses' Health Study IIAge-adjusted relative riskOral contraceptive historiesNurses' Health StudyProgression of MSDiagnosis of MSDuration of useCohort studyMS incidenceMS riskHormonal contraceptionMultiple sclerosisContraceptive historyRelative riskClinical dataProbable casesU.S. womenPast users
1999
Oral contraceptive use and risk of melanoma in premenopausal women
Feskanich D, Hunter DJ, Willett WC, Spiegelman D, Stampfer MJ, Speizer FE, Colditz GA. Oral contraceptive use and risk of melanoma in premenopausal women. British Journal Of Cancer 1999, 81: 918-923. PMID: 10555769, PMCID: PMC2374297, DOI: 10.1038/sj.bjc.6690787.Peer-Reviewed Original ResearchConceptsCurrent OC usersOral contraceptive useRisk of melanomaOC usersRisk factorsContraceptive useSun exposureHealth Study II cohortLow-dose oestrogen pillsPast OC usersBody mass indexPossible risk factorsLonger durationPremenopausal white womenLogistic regression modelsNHS IIOC usePremenopausal womenSignificant twofold increaseMass indexSuperficial spreadingNodular melanomaSkin reactionsIncidence rateSunburn history
1998
A prospective study of reproductive factors and oral contraceptive use in relation to the risk of uterine leiomyomata
Marshall L, Spiegelman D, Goldman M, Manson J, Colditz G, Barbieri R, Stampfer M, Hunter D. A prospective study of reproductive factors and oral contraceptive use in relation to the risk of uterine leiomyomata. Fertility And Sterility 1998, 70: 432-439. PMID: 9757871, DOI: 10.1016/s0015-0282(98)00208-8.Peer-Reviewed Original ResearchConceptsOral contraceptive useUterine leiomyomataContraceptive useReproductive factorsOral contraceptivesProspective studySelf-reported uterine leiomyomataHistory of infertilitySelf-reported diagnosisPremenopausal nursesPremenopausal womenMedical recordsRisk factorsMAIN OUTCOMEElevated riskLast birthLeiomyomataYounger ageFirst birthNotable associationAge 13HysterectomyContraceptivesRiskAge
1997
Variation in the incidence of uterine leiomyoma among premenopausal women by age and race.
Marshall LM, Spiegelman D, Barbieri RL, Goldman MB, Manson JE, Colditz GA, Willett WC, Hunter DJ. Variation in the incidence of uterine leiomyoma among premenopausal women by age and race. Obstetrics And Gynecology 1997, 90: 967-73. PMID: 9397113, DOI: 10.1016/s0029-7844(97)00534-6.Peer-Reviewed Original ResearchConceptsUterine leiomyomaRelative riskPremenopausal womenRisk factorsIncidence rateFirst oral contraceptive useWhite womenBlack womenOral contraceptive useBody mass indexHistory of infertilityPremenopausal black womenSimilar relative riskPotential risk factorsSelf-reported diagnosisAge-standardized ratesCurrent alcohol consumptionRace-specific ratesMass indexPhysical examinationPelvic examinationMedical recordsHigh prevalenceContraceptive useLast birthOral Contraceptives and Ovulatory Causes of Delayed Fertility
Chasan-Taber L, Willett W, Stampfer M, Spiegelman D, Rosner B, Hunter D, Colditz G, Manson J. Oral Contraceptives and Ovulatory Causes of Delayed Fertility. American Journal Of Epidemiology 1997, 146: 258-265. PMID: 9247010, DOI: 10.1093/oxfordjournals.aje.a009261.Peer-Reviewed Original ResearchConceptsOvulatory causeOral contraceptivesMultivariate relative riskOral contraceptive useReturn of fertilityHistory of infertilityCase-control studyPercent of casesDuration of useMethod of contraceptionOvulatory infertilityPrevious pregnancyEventual pregnancyHormonal disordersRelative riskContraceptive useYounger agePregnancyMarried nursesNursesWomenContraceptivesInfertilityDelayed fertilityFirst useA Prospective Study of Oral Contraceptives and NIDDM Among U.S. Women
Chasan-Taber L, Willett W, Stampfer M, Hunter D, Colditz G, Spiegelman D, Manson J. A Prospective Study of Oral Contraceptives and NIDDM Among U.S. Women. Diabetes Care 1997, 20: 330-335. PMID: 9051382, DOI: 10.2337/diacare.20.3.330.Peer-Reviewed Original ResearchConceptsOral contraceptivesRelative riskPast usersProspective studyModern oral contraceptivesU.S. female nursesMultivariate relative riskOral contraceptive useProspective cohort studyLarge prospective studiesLow absolute riskCoronary heart diseaseCurrent usersHistory of diagnosisDiagnosed diabetesCohort studyElevated cholesterolAlcohol intakeCigarette smokingIncident casesSymptomatic casesAbsolute riskExcess riskHeart diseaseFamily history
1996
Prospective study of oral contraceptives and hypertension among women in the United States.
Chasan-Taber L, Willett W, Manson J, Spiegelman D, Hunter D, Curhan G, Colditz G, Stampfer M. Prospective study of oral contraceptives and hypertension among women in the United States. Circulation 1996, 94: 483-9. PMID: 8759093, DOI: 10.1161/01.cir.94.3.483.Peer-Reviewed Original ResearchConceptsOral contraceptivesBody mass indexMass indexRelative riskFamily historyAge-adjusted relative riskPast usersHigh-dose pillsMultivariate relative riskOral contraceptive useProspective cohort studyRisk of hypertensionCoronary heart diseaseRisk of developmentLow-dose formulationsCurrent usersMicrograms estrogenHypertensive effectCohort studyEffect of ageBlood pressureAlcohol intakeCigarette smokingIncident casesProspective study