2020
Impaired Hematological Status Increases the Risk of Mortality among HIV-Infected Adults Initiating Antiretroviral Therapy in Tanzania
Noor RA, Abioye AI, Hertzmark E, Darling AM, Aboud S, Mugusi FM, Sudfeld CR, Spiegelman D, Fawzi WW. Impaired Hematological Status Increases the Risk of Mortality among HIV-Infected Adults Initiating Antiretroviral Therapy in Tanzania. Journal Of Nutrition 2020, 150: 2375-2382. PMID: 32621487, PMCID: PMC7540061, DOI: 10.1093/jn/nxaa172.Peer-Reviewed Original ResearchConceptsRisk of mortalityPrevalence of anemiaHAART initiationHematological statusIron deficiencyAntiretroviral therapySerum ferritinSevere anemiaIncident clinical outcomesRelation of anemiaTrial of multivitaminsActive antiretroviral therapyHIV disease progressionCase-cohort studyIron deficiency anemiaProportional hazards modelElevated ironNonanemic participantsHIV patientsMultivariate adjustmentClinical outcomesMorbidity outcomesAnemia etiologyDeficiency anemiaIron supplementation
2004
Physical activity and risk of coronary heart disease in India
Rastogi T, Vaz M, Spiegelman D, Reddy KS, Bharathi A, Stampfer MJ, Willett WC, Ascherio A. Physical activity and risk of coronary heart disease in India. International Journal Of Epidemiology 2004, 33: 759-767. PMID: 15044412, DOI: 10.1093/ije/dyh042.Peer-Reviewed Original ResearchConceptsLeisure-time exerciseCHD riskRisk factorsPhysical activityPhysical exerciseSedentary activitiesHospital-based case-control studyCoronary heart disease riskDisease riskHeart disease riskCoronary heart diseaseAcute myocardial infarctionRisk of CHDSex-adjusted analysesCase-control studyConditional logistic regressionPhysical inactivity levelsMultivariate adjustmentBrisk walkingMyocardial infarctionHeart diseaseRelative riskSedentary lifestyleElevated riskMultivariate analysis
2003
The Use of B Vitamin Supplements and Peripheral Arterial Disease Risk in Men Are Inversely Related
Merchant AT, Hu FB, Spiegelman D, Willett WC, Rimm EB, Ascherio A. The Use of B Vitamin Supplements and Peripheral Arterial Disease Risk in Men Are Inversely Related. Journal Of Nutrition 2003, 133: 2863-2867. PMID: 12949378, DOI: 10.1093/jn/133.9.2863.Peer-Reviewed Original ResearchConceptsPeripheral arterial diseasePAD riskFolate intakePrevention of PADPeripheral arterial disease riskVitamin BArterial disease riskIncident PAD casesU.S. health professionalsB vitamin intakeVitamin supplement useB-vitamin supplementsCoronary heart diseaseWeak inverse associationMultivariate adjustmentArterial diseaseVitamin intakeSupplement useHeart diseaseInverse associationCardiovascular diseaseD incrementStudy populationVitamin supplementsDietary folate
2002
Vitamin and carotenoid intake and risk of squamous cell carcinoma of the skin
Fung TT, Spiegelman D, Egan KM, Giovannucci E, Hunter DJ, Willett WC. Vitamin and carotenoid intake and risk of squamous cell carcinoma of the skin. International Journal Of Cancer 2002, 103: 110-115. PMID: 12455062, DOI: 10.1002/ijc.10798.Peer-Reviewed Original ResearchConceptsCases of SCCHEALTHY studyProspective cohort study designMale health professionalsHealth Professionals FollowCohort study designIntake of vitaminsSquamous cell carcinomaSignificant inverse associationDevelopment of SCCImportant protective roleIncidence of SCCBiennial questionnairesProfessionals FollowMultivariate adjustmentCell carcinomaSCC incidenceDietary factorsInverse associationMedical recordsRisk factorsRelative riskLarge cohortCarotenoid intakeSun exposure
2001
Prospective Study of Zinc Intake and the Risk of Age-Related Macular Degeneration
Cho E, Stampfer M, Seddon J, Hung S, Spiegelman D, Rimm E, Willett W, Hankinson S. Prospective Study of Zinc Intake and the Risk of Age-Related Macular Degeneration. Annals Of Epidemiology 2001, 11: 328-336. PMID: 11399447, DOI: 10.1016/s1047-2797(01)00217-4.Peer-Reviewed Original ResearchConceptsAge-related macular degenerationZinc intakeRelative riskProspective studyLowest quintileMacular degenerationRisk of AMDDiagnosis of AMDSemiquantitative food frequency questionnaireMultivariate relative riskPooled relative riskFood frequency questionnaireLarge prospective studiesDietary zinc intakeVisual acuity lossTotal zinc intakePotential risk factorsRisk of AgeMultivariate adjustmentIncident casesAcuity lossHighest quintileLong-term benefitsRisk factorsZinc supplements