2011
Fatty acids in the de novo lipogenesis pathway and risk of coronary heart disease: the Cardiovascular Health Study
Wu J, Lemaitre RN, Imamura F, King IB, Song X, Spiegelman D, Siscovick DS, Mozaffarian D. Fatty acids in the de novo lipogenesis pathway and risk of coronary heart disease: the Cardiovascular Health Study. American Journal Of Clinical Nutrition 2011, 94: 431-438. PMID: 21697077, PMCID: PMC3142722, DOI: 10.3945/ajcn.111.012054.Peer-Reviewed Original ResearchConceptsCoronary heart diseaseNonfatal myocardial infarctionSudden cardiac arrestFatal coronary heart diseaseTotal coronary heart diseaseIncident coronary heart diseaseDe novo lipogenesisHigh riskCHD eventsHeart diseaseMultivariable-adjusted Cox proportional hazardsCommunity-based prospective studySecondary analysisCardiovascular disease risk factorsCardiovascular Health StudyDisease risk factorsFatty acidsCox proportional hazardsDe novo lipogenesis pathwayCHD deathCHD outcomesProspective studyCardiac arrestMyocardial infarctionMedical records
2002
Vitamin and carotenoid intake and risk of squamous cell carcinoma of the skin
Fung TT, Spiegelman D, Egan KM, Giovannucci E, Hunter DJ, Willett WC. Vitamin and carotenoid intake and risk of squamous cell carcinoma of the skin. International Journal Of Cancer 2002, 103: 110-115. PMID: 12455062, DOI: 10.1002/ijc.10798.Peer-Reviewed Original ResearchConceptsCases of SCCHEALTHY studyProspective cohort study designMale health professionalsHealth Professionals FollowCohort study designIntake of vitaminsSquamous cell carcinomaSignificant inverse associationDevelopment of SCCImportant protective roleIncidence of SCCBiennial questionnairesProfessionals FollowMultivariate adjustmentCell carcinomaSCC incidenceDietary factorsInverse associationMedical recordsRisk factorsRelative riskLarge cohortCarotenoid intakeSun exposure
1998
A prospective study of reproductive factors and oral contraceptive use in relation to the risk of uterine leiomyomata
Marshall L, Spiegelman D, Goldman M, Manson J, Colditz G, Barbieri R, Stampfer M, Hunter D. A prospective study of reproductive factors and oral contraceptive use in relation to the risk of uterine leiomyomata. Fertility And Sterility 1998, 70: 432-439. PMID: 9757871, DOI: 10.1016/s0015-0282(98)00208-8.Peer-Reviewed Original ResearchConceptsOral contraceptive useUterine leiomyomataContraceptive useReproductive factorsOral contraceptivesProspective studySelf-reported uterine leiomyomataHistory of infertilitySelf-reported diagnosisPremenopausal nursesPremenopausal womenMedical recordsRisk factorsMAIN OUTCOMEElevated riskLast birthLeiomyomataYounger ageFirst birthNotable associationAge 13HysterectomyContraceptivesRiskAge
1997
Variation in the incidence of uterine leiomyoma among premenopausal women by age and race.
Marshall LM, Spiegelman D, Barbieri RL, Goldman MB, Manson JE, Colditz GA, Willett WC, Hunter DJ. Variation in the incidence of uterine leiomyoma among premenopausal women by age and race. Obstetrics And Gynecology 1997, 90: 967-73. PMID: 9397113, DOI: 10.1016/s0029-7844(97)00534-6.Peer-Reviewed Original ResearchConceptsUterine leiomyomaRelative riskPremenopausal womenRisk factorsIncidence rateFirst oral contraceptive useWhite womenBlack womenOral contraceptive useBody mass indexHistory of infertilityPremenopausal black womenSimilar relative riskPotential risk factorsSelf-reported diagnosisAge-standardized ratesCurrent alcohol consumptionRace-specific ratesMass indexPhysical examinationPelvic examinationMedical recordsHigh prevalenceContraceptive useLast birth