2024
Improving lifestyle behaviors during chemotherapy for breast cancer: The Lifestyle, Exercise, and Nutrition Early After Diagnosis (LEANer) Trial
Puklin L, Ferrucci L, Harrigan M, McGowan C, Zupa M, Cartmel B, Li F, Ligibel J, Spiegelman D, Sharifi M, Sanft T, Irwin M. Improving lifestyle behaviors during chemotherapy for breast cancer: The Lifestyle, Exercise, and Nutrition Early After Diagnosis (LEANer) Trial. Cancer 2024, 130: 2440-2452. PMID: 38470431, PMCID: PMC11214600, DOI: 10.1002/cncr.35280.Peer-Reviewed Original ResearchPhysical activityDiet qualityHEI-2015Strength trainingLifestyle behaviorsHealthy Eating Index (HEI)-2015Breast cancerAssociated with baseline fatigueImprove physical activityImprove lifestyle behaviorsHigher HEI-2015Associated with higher oddsExercise interventionUsual careIntervention armIntervention groupBaseline fatigueLifestyle interventionYearlong interventionLower fatigueHigher oddsSecondary analysisLogistic regressionNewly diagnosed patientsStudy arms
2023
Factors associated with receiving results and attending colposcopy in patients with positive HPV screens in Mexico City
León-Maldonado L, Hernández-Ramírez R, Torres-Ibarra L, Spiegelman D, Sheth S, Lazcano E, Cadena-Fiscal J, Salmerón J. Factors associated with receiving results and attending colposcopy in patients with positive HPV screens in Mexico City. Preventive Medicine Reports 2023, 35: 102347. PMID: 37593354, PMCID: PMC10428024, DOI: 10.1016/j.pmedr.2023.102347.Peer-Reviewed Original ResearchPercent of participantsColposcopy appointmentHealthcare facilitiesHigh-risk human papillomavirusMultivariable logistic regressionHealthcare system factorsScreening resultsPositive screening resultsColposcopy adherenceColposcopy clinicHPV screenPrevious PapMedian ageCervical cancerPap testHuman papillomavirusHigh school educationPatientsGreater adherenceExperienced nursesGood complianceLogistic regressionScheduling appointmentsLimited staff availabilityAdherenceAssociation between cancer stigma and cervical cancer screening uptake among women of Dhulikhel and Banepa, Nepal
Paneru B, Karmacharya A, Bharati A, Makaju S, Adhikari B, Kafle D, Shakya S, Spiegelman D, Seth S, Stangl A, Shrestha A, Shrestha A. Association between cancer stigma and cervical cancer screening uptake among women of Dhulikhel and Banepa, Nepal. PLOS ONE 2023, 18: e0285771. PMID: 37200234, PMCID: PMC10194964, DOI: 10.1371/journal.pone.0285771.Peer-Reviewed Original ResearchConceptsCervical cancer screening uptakeCancer screening uptakeScreening uptakeMultivariable logistic regressionCancer Stigma ScaleCancer stigmaCervical cancerAge of menarcheFirst sexual intercourseLogistic regressionNepalese womenSexual intercourseReproductive health variablesCervical cancer screeningEffective screening programsSemi-urban areasCross-sectional studyPercent of womenMean total scoreFamily planning usersScreening servicesCancer screeningCommon cancerDisease burdenScreening program
2020
Erythrocyte membrane fatty acids and breast cancer risk by tumor tissue expression of immuno-inflammatory markers and fatty acid synthase: a nested case-control study
McGee EE, Kim CH, Wang M, Spiegelman D, Stover DG, Heng YJ, Collins LC, Baker GM, Farvid MS, Schedin P, Jindal S, Tamimi RM, Eliassen AH. Erythrocyte membrane fatty acids and breast cancer risk by tumor tissue expression of immuno-inflammatory markers and fatty acid synthase: a nested case-control study. Breast Cancer Research 2020, 22: 78. PMID: 32698885, PMCID: PMC7374956, DOI: 10.1186/s13058-020-01316-4.Peer-Reviewed Original ResearchConceptsBreast cancer riskImmuno-inflammatory markersErythrocyte membrane fatty acidsCase-control studyTumor tissue expressionFatty acid synthaseCancer riskTrans fatty acidsExpression subtypesOdds ratioSpecific fatty acidsLogistic regressionHealth Study IITumor tissue blocksMembrane fatty acidsFatty acidsUnconditional logistic regressionConfidence intervalsTissue expressionT cell functionPolytomous logistic regressionAcid synthaseTumor CD4Potential confoundersTumor expression
2007
Regression calibration for logistic regression with multiple surrogates for one exposure
Weller E, Milton D, Eisen E, Spiegelman D. Regression calibration for logistic regression with multiple surrogates for one exposure. Journal Of Statistical Planning And Inference 2007, 137: 449-461. DOI: 10.1016/j.jspi.2006.01.009.Peer-Reviewed Original ResearchCross-sectional epidemiologic studyExposure measurementsExposure-response associationsQuantitative exposure measurementsLung functionBaseline prevalenceExposure measurement errorOccupational exposureEpidemiologic studiesFluid exposureHealth outcomesExposure assessment studiesLogistic regressionIndividual exposurePersonal monitors
2002
Intake of alcohol and alcoholic beverages and the risk of basal cell carcinoma of the skin.
Fung TT, Hunter DJ, Spiegelman D, Colditz GA, Rimm EB, Willett WC. Intake of alcohol and alcoholic beverages and the risk of basal cell carcinoma of the skin. Cancer Epidemiology Biomarkers & Prevention 2002, 11: 1119-22. PMID: 12376519.Peer-Reviewed Original ResearchConceptsAlcohol intakeSun sensitivity factorsMultivariate relative riskTotal alcohol intakeFood frequency questionnaireRisk of BCCBasal cell carcinomaIntake of alcoholPooled logistic regressionAlcoholic beveragesLast physical examinationCases of BCCFrequency questionnaireMultivitamin useSignificant positive associationCell carcinomaPhysical examinationInverse associationRelative riskLarge cohortSun exposureOutdoor walkingLogistic regressionIntakeMore alcoholVitamins and carotenoids intake and the risk of basal cell carcinoma of the skin in women (United States)
Fung TT, Hunter DJ, Spiegelman D, Colditz GA, Speizer FE, Willett WC. Vitamins and carotenoids intake and the risk of basal cell carcinoma of the skin in women (United States). Cancer Causes & Control 2002, 13: 221-230. PMID: 12020103, DOI: 10.1023/a:1015036317596.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge DistributionAscorbic AcidCarcinoma, Basal CellCarotenoidsCohort StudiesConfidence IntervalsDietDietary SupplementsFemaleHumansIncidenceLogistic ModelsMiddle AgedProbabilityProspective StudiesRisk AssessmentSensitivity and SpecificitySkin NeoplasmsUnited StatesVitamin AVitamin EVitaminsConceptsBasal cell carcinomaVitamin ACell carcinomaDietary intakeRelative riskSun sensitivity factorsMultivariate relative riskFood frequency questionnaireRisk of BCCSignificant inverse associationIncidence of BCCImportant protective roleFirst diagnosisDietary factorsInverse associationSun exposureLatency periodProtective roleSpecific carotenoidsLogistic regressionVitamin CBottom quintileIntakeCarcinomaRiskDietary and Adipose Tissue Gamma-Tocopherol and Risk of Myocardial Infarction
El-Sohemy A, Baylin A, Spiegelman D, Ascherio A, Campos H. Dietary and Adipose Tissue Gamma-Tocopherol and Risk of Myocardial Infarction. Epidemiology 2002, 13: 216-223. PMID: 11880764, DOI: 10.1097/00001648-200203000-00018.Peer-Reviewed Original ResearchConceptsDietary vitamin EMyocardial infarctionGamma-tocopherolOdds ratioVitamin ENonfatal myocardial infarctionFood frequency questionnaireCoronary heart diseasePopulation-based studyFirst myocardial infarctionConfidence intervalsConditional logistic regressionAdipose tissue samplesHighest quintileSupplement usersLowest quintileHeart diseaseInverse associationDietary intakeLower riskSubstantial inverse associationMultivariate analysisLogistic regressionTissue samplesWeak association
1998
Physical Activity and Breast Cancer Risk in a Cohort of Young Women
Rockhill B, Willett W, Hunter D, Manson J, Hankinson S, Spiegelman D, Colditz G. Physical Activity and Breast Cancer Risk in a Cohort of Young Women. Journal Of The National Cancer Institute 1998, 90: 1555-1160. PMID: 9701365, DOI: 10.1093/jnci/90.15.1155.Peer-Reviewed Original ResearchConceptsBreast cancer riskHealth Study IIPhysical activityRelative riskBreast cancerCancer riskNurses' Health Study IIRR of cancerBreast cancer preventionInvasive breast cancerStrenuous physical activityConfidence intervalsLate adolescenceNonoccupational physical activityYoung adult womenProspective studyNonoccupational activitiesActive womenCancer preventionReduced riskStrenuous activityAdult womenAge 18Logistic regressionYoung womenCorrecting for bias in relative risk estimates due to exposure measurement error: a case study of occupational exposure to antineoplastics in pharmacists.
Spiegelman D, Valanis B. Correcting for bias in relative risk estimates due to exposure measurement error: a case study of occupational exposure to antineoplastics in pharmacists. American Journal Of Public Health 1998, 88: 406-12. PMID: 9518972, PMCID: PMC1508329, DOI: 10.2105/ajph.88.3.406.Peer-Reviewed Original ResearchConceptsMeasurement error modelInterval estimatesExposure measurement errorMeasurement errorError modelPrevalence ratiosRelative riskLikelihood-based methodsLog relative riskNondifferential measurement errorStatistical methodsRelative risk estimatesOutcomes of interestOccupational exposurePublic health researchHospital pharmacistsLogistic regressionRisk estimatesWeekly numberFirst methodHealth effectsUsual pointHealth researchErrorPharmacists
1997
Regression calibration method for correcting measurement-error bias in nutritional epidemiology
Spiegelman D, McDermott A, Rosner B. Regression calibration method for correcting measurement-error bias in nutritional epidemiology. American Journal Of Clinical Nutrition 1997, 65: s1179-s1186. PMID: 9094918, DOI: 10.1093/ajcn/65.4.1179s.Peer-Reviewed Original ResearchConceptsHealth StudyDietary intakeMassachusetts Women's Health StudyUltradistal radius bone densityCox proportional hazards modelRadius bone densityNurses' Health StudyWomen's Health StudyIncidence rate ratiosRate ratioProportional hazards modelOdds ratioBone densityBreast cancerHazards modelVitamin ANutritional epidemiologyLogistic regressionGold standardLinear regression modelsEpidemiologyIntakeRegression modelsValidation studyPerson error
1992
Correction of Logistic Regression Relative Risk Estimates and Confidence Intervals for Random Within-Person Measurement Error
Rosner B, Spiegelman D, Willett WC. Correction of Logistic Regression Relative Risk Estimates and Confidence Intervals for Random Within-Person Measurement Error. American Journal Of Epidemiology 1992, 136: 1400-1413. PMID: 1488967, DOI: 10.1093/oxfordjournals.aje.a116453.Peer-Reviewed Original ResearchConceptsRelative risk estimatesRisk factorsLogistic regressionRisk estimatesCoronary risk factorsCoronary heart diseaseGold standardConfidence intervalsFramingham Heart StudyExamination 4Extreme quintilesHeart diseaseOdds ratioHeart StudyExamination 2Exposure assessmentSubstudyCovariatesMenMain studyReproducibility dataRegressionFactorsQuintileIncidence
1990
CORRECTION OF LOGISTIC REGRESSION RELATIVE RISK ESTIMATES AND CONFIDENCE INTERVALS FOR MEASUREMENT ERROR: THE CASE OF MULTIPLE COVARIATES MEASURED WITH ERROR
ROSNER B, SPIEGELMAN D, WILLETT WC. CORRECTION OF LOGISTIC REGRESSION RELATIVE RISK ESTIMATES AND CONFIDENCE INTERVALS FOR MEASUREMENT ERROR: THE CASE OF MULTIPLE COVARIATES MEASURED WITH ERROR. American Journal Of Epidemiology 1990, 132: 734-745. PMID: 2403114, DOI: 10.1093/oxfordjournals.aje.a115715.Peer-Reviewed Original ResearchConceptsAge-adjusted relative riskRelative riskRisk factorsFat intakeMultiple logistic regression modelBreast cancer riskConfidence intervalsTrue risk factorRelative risk estimatesValidation studyLogistic regression modelsMultivariate linear regression modelRegression modelsAlcohol intakeProspective studyDietary fatBreast cancerCancer riskLogistic regressionRisk estimatesIntakeRiskSeparate validation studyContinuous variablesPositive association