2005
Alcohol consumption and high-density lipoprotein levels: the effect of ADH1C genotype, gender and menopausal status
Hines LM, Hunter DJ, Stampfer MJ, Spiegelman D, Chu NF, Rifai N, Hankinson SE, Rimm EB. Alcohol consumption and high-density lipoprotein levels: the effect of ADH1C genotype, gender and menopausal status. Atherosclerosis 2005, 182: 293-300. PMID: 16051248, DOI: 10.1016/j.atherosclerosis.2005.02.005.Peer-Reviewed Original ResearchConceptsHigh-density lipoprotein levelsPostmenopausal hormonesPostmenopausal womenModerate alcohol consumptionHDL levelsOlder-aged menPremenopausal womenAlcohol consumptionADH1C genotypeLipoprotein levelsAged menCoronary heart diseaseMenopausal statusExogenous estrogenMyocardial infarctionHeart diseaseModerate drinkersOlder menFunctional polymorphismsWomenType 1CMenVaried exposureAssociationHigh levels
1998
A prospective study of methylenetetrahydrofolate reductase and methionine synthase gene polymorphisms, and risk of colorectal adenoma.
Chen J, Giovannucci E, Hankinson SE, Ma J, Willett WC, Spiegelman D, Kelsey KT, Hunter DJ. A prospective study of methylenetetrahydrofolate reductase and methionine synthase gene polymorphisms, and risk of colorectal adenoma. Carcinogenesis 1998, 19: 2129-2132. PMID: 9886567, DOI: 10.1093/carcin/19.12.2129.Peer-Reviewed Original ResearchConceptsVal/Val polymorphismColorectal adenomasMethylenetetrahydrofolate reductase (MTHFR) geneHealth StudyProspective Nurses' Health StudyNurses' Health StudyRisk of adenomaVal polymorphismSynthase gene polymorphismsMethionine synthase geneLack of associationPolyp casesProspective studyColorectal cancerGly polymorphismBenign adenomasGene polymorphismsAdenomasColorectal tumorigenesisMalignant transformationFunctional polymorphismsMethylenetetrahydrofolate reductaseMethionine synthase gene polymorphismsRiskPolymorphism