2004
A Randomized Trial of Multivitamin Supplements and HIV Disease Progression and Mortality
Fawzi WW, Msamanga GI, Spiegelman D, Wei R, Kapiga S, Villamor E, Mwakagile D, Mugusi F, Hertzmark E, Essex M, Hunter DJ. A Randomized Trial of Multivitamin Supplements and HIV Disease Progression and Mortality. New England Journal Of Medicine 2004, 351: 23-32. PMID: 15229304, DOI: 10.1056/nejmoa040541.Peer-Reviewed Original ResearchConceptsVitamin AHIV diseaseMultivitamin supplementsHuman immunodeficiency virus (HIV) diseasePlacebo-controlled trialHIV disease progressionStage 4 diseaseLow viral loadHigher CD4Antiretroviral therapyPrimary outcomeImmunodeficiency syndromeRandomized trialsViral loadPregnant womenDisease progressionRelative riskObservational studyDaily supplementCell countEnd pointMicronutrient statusMultivitaminsDiseaseProgression
1998
Study of Prediagnostic Selenium Level in Toenails and the Risk of Advanced Prostate Cancer
Yoshizawa K, Willett W, Morris S, Stampfer M, Spiegelman D, Rimm E, Giovannucci E. Study of Prediagnostic Selenium Level in Toenails and the Risk of Advanced Prostate Cancer. Journal Of The National Cancer Institute 1998, 90: 1219-1224. PMID: 9719083, DOI: 10.1093/jnci/90.16.1219.Peer-Reviewed Original ResearchConceptsAdvanced prostate cancerProstate cancerProspective studyControl subjectsHealth professionalsSelenium levelsMale health professionalsFurther prospective studiesBody mass indexLong-term selenium intakeSelenium intakeCase-control designHigh selenium intakeLycopene intakeCalcium intakeMass indexPrediagnostic levelsRandomized trialsSmoking statusFat intakeIntervention trialsFamily historyCohort membersDaily supplementToenail clippings