2022
Iron supplementation and paediatric HIV disease progression: a cohort study among children receiving routine HIV care in Dar es Salaam, Tanzania
Andersen CT, Duggan CP, Manji K, Seage GR, Spiegelman D, Perumal N, Ulenga N, Fawzi WW. Iron supplementation and paediatric HIV disease progression: a cohort study among children receiving routine HIV care in Dar es Salaam, Tanzania. International Journal Of Epidemiology 2022, 51: 1533-1543. PMID: 35167662, PMCID: PMC9557856, DOI: 10.1093/ije/dyac017.Peer-Reviewed Original ResearchConceptsDisease stage progressionIron supplementationStage progressionCohort studyDisease progressionRoutine HIV careHIV disease progressionProspective cohort studyManagement of anemiaRisk of anemiaHigher hazard rateProportional hazards modelIron supplement useDar es SalaamHaematological outcomesAntiretroviral therapyHIV careClinic visitsSupportive careAntiretroviral treatmentClinical outcomesClinical visitsAnemia statusSupplement useVital status
2020
Impaired Hematological Status Increases the Risk of Mortality among HIV-Infected Adults Initiating Antiretroviral Therapy in Tanzania
Noor RA, Abioye AI, Hertzmark E, Darling AM, Aboud S, Mugusi FM, Sudfeld CR, Spiegelman D, Fawzi WW. Impaired Hematological Status Increases the Risk of Mortality among HIV-Infected Adults Initiating Antiretroviral Therapy in Tanzania. Journal Of Nutrition 2020, 150: 2375-2382. PMID: 32621487, PMCID: PMC7540061, DOI: 10.1093/jn/nxaa172.Peer-Reviewed Original ResearchConceptsRisk of mortalityPrevalence of anemiaHAART initiationHematological statusIron deficiencyAntiretroviral therapySerum ferritinSevere anemiaIncident clinical outcomesRelation of anemiaTrial of multivitaminsActive antiretroviral therapyHIV disease progressionCase-cohort studyIron deficiency anemiaProportional hazards modelElevated ironNonanemic participantsHIV patientsMultivariate adjustmentClinical outcomesMorbidity outcomesAnemia etiologyDeficiency anemiaIron supplementation
2011
Anemia in TB patients predicts recurrence and mortality
Isanaka S, Mugusi F, Urassa W, Bosch R, Villamor E, Spiegelman D, Duggan C, Fawzi W. Anemia in TB patients predicts recurrence and mortality. The FASEB Journal 2011, 25: 779.14-779.14. DOI: 10.1096/fasebj.25.1_supplement.779.14.Peer-Reviewed Original ResearchTreatment failureIron deficiencyHypochromic microcytosisHIV-TB patientsCause of anemiaPoor clinical outcomeRisk of recurrenceMeasures of anemiaTuberculosis recurrenceHIV patientsTB patientsClinical outcomesSevere anemiaRisk factorsAnemiaOverall healthPatientsRecurrenceMortalityRiskMicrocytosisSignificant improvementAssociationDeficiencyFocused management
2004
Selenium Status Is Associated with Accelerated HIV Disease Progression among HIV-1–Infected Pregnant Women in Tanzania
Kupka R, Msamanga GI, Spiegelman D, Morris S, Mugusi F, Hunter DJ, Fawzi WW. Selenium Status Is Associated with Accelerated HIV Disease Progression among HIV-1–Infected Pregnant Women in Tanzania. Journal Of Nutrition 2004, 134: 2556-2560. PMID: 15465747, DOI: 10.1093/jn/134.10.2556.Peer-Reviewed Original ResearchConceptsPlasma selenium levelsCD4 cell countRisk of mortalityDisease progressionHIV-1-infected pregnant womenCell countSelenium levelsLow plasma selenium levelsHIV disease progressionAccelerated disease progressionCox multivariate modelSelenium statusMedian followHIV diseaseClinical outcomesPregnant womenPoor survivalTanzanian womenMultivariate modelL increaseCells/ProgressionWomenMortalityFirst year
2001
The correlates of dietary intake among HIV-positive adults 1 , 2 , 3
Kim J, Spiegelman D, Rimm E, Gorbach S. The correlates of dietary intake among HIV-positive adults 1 , 2 , 3. American Journal Of Clinical Nutrition 2001, 74: 852-861. PMID: 11722969, DOI: 10.1093/ajcn/74.6.852.Peer-Reviewed Original ResearchConceptsHigher energy intakeDietary intakeEnergy intakeHIV infectionClinical outcomesDietary adequacyAdverse clinical outcomesAbsence of nauseaInadequate dietary intakeInadequate protein intakeInadequate energy intakeInjection drug usersCross-sectional studyStudy cohortFemale sexDiet recordsReduced appetiteDietary inadequacyStudy populationProtein intakeDietary allowanceDrug usersDiverse cohortIntakeWeight loss