2021
Religion, spirituality and diurnal rhythms of salivary cortisol and dehydroepiandrosterone in postmenopausal women
Isehunwa OO, Warner ET, Spiegelman D, Huang T, Tworoger SS, Kent BV, Shields AE. Religion, spirituality and diurnal rhythms of salivary cortisol and dehydroepiandrosterone in postmenopausal women. Comprehensive Psychoneuroendocrinology 2021, 7: 100064. PMID: 34308392, PMCID: PMC8297624, DOI: 10.1016/j.cpnec.2021.100064.Peer-Reviewed Original ResearchCortisol/DHEA ratioHPA axis biomarkersDHEA ratioHigher cortisol/DHEA ratioNurses' Health Study II participantsDiurnal rhythmCross-sectional associationsLate sleep schedulesHigher cortisol levelsPostmenopausal womenAdrenal axisCortisol levelsHealth outcomesPotential covariatesDehydroepiandrosteroneCortisolSalivary cortisolSaliva samplesObserved associationsS measuresWomenExperience scoresAssociationBiomarkersSleep scheduleDepression, Religiosity, and Telomere Length in the Study on Stress, Spirituality, and Health (SSSH)
Isehunwa OO, Warner ET, Spiegelman D, Zhang Y, Palmer JR, Kanaya AM, Cole SA, Tworoger SS, Shields LO, Gu Y, Kent BV, De Vivo I, Shields AE. Depression, Religiosity, and Telomere Length in the Study on Stress, Spirituality, and Health (SSSH). International Journal Of Mental Health And Addiction 2021, 20: 1465-1484. PMID: 35747346, PMCID: PMC9211376, DOI: 10.1007/s11469-020-00455-1.Peer-Reviewed Original ResearchRelative leukocyte telomere lengthCohort-specific analysesTelomere lengthLeukocyte telomere lengthEthnic populationsQuantitative polymerase chain reactionProspective studyPolymerase chain reactionEffect modificationRace/ethnic populationsProspective associationsDepressionChain reactionAssociationEuropean ancestry populationsAncestry populationsHealthModifying influenceFurther researchPopulationResources of resilienceMixed resultsCohort
2020
The Association of Cooking Fuel Use, Dietary Intake, and Blood Pressure among Rural Women in China
Bellows AL, Spiegelman D, Du S, Jaacks LM. The Association of Cooking Fuel Use, Dietary Intake, and Blood Pressure among Rural Women in China. International Journal Of Environmental Research And Public Health 2020, 17: 5516. PMID: 32751678, PMCID: PMC7432946, DOI: 10.3390/ijerph17155516.Peer-Reviewed Original ResearchConceptsBlood pressureHigh blood pressureHousehold air pollutionDietary intakeDiastolic blood pressureSystolic blood pressureRole of dietYears of ageFatty acid-rich foodsNonpregnant womenSolid fuel useLinear mixed effects modelsSolid cooking fuelsAdverse effectsIntakeWomenMixed effects modelsPossible mediationLower ratesCooking fuel useEffects modelRural womenCooking fuelAssociationDietCoaching Intensity, Adherence to Essential Birth Practices, and Health Outcomes in the BetterBirth Trial in Utter Pradesh, India
Barnhart DA, Spiegelman D, Zigler CM, Kara N, Delaney MM, Kalita T, Maji P, Hirschhorn LR, Semrau KEA. Coaching Intensity, Adherence to Essential Birth Practices, and Health Outcomes in the BetterBirth Trial in Utter Pradesh, India. Global Health Science And Practice 2020, 8: ghsp-d-19-00317. PMID: 32127359, PMCID: PMC7108945, DOI: 10.9745/ghsp-d-19-00317.Peer-Reviewed Original ResearchConceptsEssential birth practicesSafe Childbirth ChecklistPerinatal health outcomesBirth attendantsHealth outcomesBetterBirth trialWorld Health Organization Safe Childbirth ChecklistBirth practicesQuality of careSustain behavior changeCoaching-based interventionBehavior changeFrequent coachingPerinatal mortalityBirth facilityAdherenceOutcomesGreater improvementAttendantsVisitsTrialsMonthsRegression modelsAssociationUtter Pradesh
2011
Anemia in TB patients predicts recurrence and mortality
Isanaka S, Mugusi F, Urassa W, Bosch R, Villamor E, Spiegelman D, Duggan C, Fawzi W. Anemia in TB patients predicts recurrence and mortality. The FASEB Journal 2011, 25: 779.14-779.14. DOI: 10.1096/fasebj.25.1_supplement.779.14.Peer-Reviewed Original ResearchTreatment failureIron deficiencyHypochromic microcytosisHIV-TB patientsCause of anemiaPoor clinical outcomeRisk of recurrenceMeasures of anemiaTuberculosis recurrenceHIV patientsTB patientsClinical outcomesSevere anemiaRisk factorsAnemiaOverall healthPatientsRecurrenceMortalityRiskMicrocytosisSignificant improvementAssociationDeficiencyFocused management
2005
Alcohol consumption and high-density lipoprotein levels: the effect of ADH1C genotype, gender and menopausal status
Hines LM, Hunter DJ, Stampfer MJ, Spiegelman D, Chu NF, Rifai N, Hankinson SE, Rimm EB. Alcohol consumption and high-density lipoprotein levels: the effect of ADH1C genotype, gender and menopausal status. Atherosclerosis 2005, 182: 293-300. PMID: 16051248, DOI: 10.1016/j.atherosclerosis.2005.02.005.Peer-Reviewed Original ResearchConceptsHigh-density lipoprotein levelsPostmenopausal hormonesPostmenopausal womenModerate alcohol consumptionHDL levelsOlder-aged menPremenopausal womenAlcohol consumptionADH1C genotypeLipoprotein levelsAged menCoronary heart diseaseMenopausal statusExogenous estrogenMyocardial infarctionHeart diseaseModerate drinkersOlder menFunctional polymorphismsWomenType 1CMenVaried exposureAssociationHigh levelsPlasma Carotenoids, Retinol, and Tocopherols and Risk of Breast Cancer
Tamimi RM, Hankinson SE, Campos H, Spiegelman D, Zhang S, Colditz GA, Willett WC, Hunter DJ. Plasma Carotenoids, Retinol, and Tocopherols and Risk of Breast Cancer. American Journal Of Epidemiology 2005, 161: 153-160. PMID: 15632265, DOI: 10.1093/aje/kwi030.Peer-Reviewed Original ResearchConceptsLutein/zeaxanthinBreast cancerHealth StudyPlasma carotenoidsNurses' Health StudyBreast cancer riskCase-control studyBreast cancer etiologyNodal metastasisHighest quintileInvasive cancerLowest quintileBlood drawInverse associationCancer riskAlpha-tocopherolCancerCancer etiologyGamma-tocopherolWomenRetinolQuintileRiskRole of carotenoidsAssociation
2004
Changes in whole-grain, bran, and cereal fiber consumption in relation to 8-y weight gain among men
Koh-Banerjee P, Franz M, Sampson L, Liu S, Jacobs DR, Spiegelman D, Willett W, Rimm E. Changes in whole-grain, bran, and cereal fiber consumption in relation to 8-y weight gain among men. American Journal Of Clinical Nutrition 2004, 80: 1237-1245. PMID: 15531671, DOI: 10.1093/ajcn/80.5.1237.Peer-Reviewed Original ResearchConceptsWhole-grain intakeLong-term weight gainWeight gainBody weightWhole grainsWhole grain consumptionDose-response relationProspective cohortLifestyle factorsD incrementMethodologic inconsistenciesFiber intakeSelf-report questionnairesEpidemiologic studiesUS menMetabolic alterationsFiber consumptionMultivariate analysisIntakeMenAssociationBreastfeeding and maternal HIV-1 disease progression and mortality
Sedgh G, Spiegelman D, Larsen U, Msamanga G, Fawzi WW. Breastfeeding and maternal HIV-1 disease progression and mortality. AIDS 2004, 18: 1043-1049. PMID: 15096808, DOI: 10.1097/00002030-200404300-00013.Peer-Reviewed Original ResearchConceptsHIV-1 disease progressionCD4 cell countDisease progressionCell countHigher CD4 cell countsLow CD4 cell countsCox proportional hazards modelHealth of HIVCohort study designExcessive weight lossProportional hazards modelPartial breastfeedingRelative riskHazards modelInsufficient evidenceBreastfeedingMultivariate analysisStudy designWeight lossWomenProgressionDar es SalaamHIVDeathAssociation
2003
The HRAS1 variable number of tandem repeats and risk of breast cancer.
Tamimi RM, Hankinson SE, Ding S, Gagalang V, Larson GP, Spiegelman D, Colditz GA, Krontiris TG, Hunter DJ. The HRAS1 variable number of tandem repeats and risk of breast cancer. Cancer Epidemiology Biomarkers & Prevention 2003, 12: 1528-30. PMID: 14693748.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAllelesBreast NeoplasmsCase-Control StudiesDNA, NeoplasmFemaleGenes, rasGenetic Predisposition to DiseaseGenotypeHumansLogistic ModelsMiddle AgedMinisatellite RepeatsPolymerase Chain ReactionPolymorphism, GeneticProbabilityPrognosisReference ValuesRisk AssessmentSensitivity and SpecificityTandem Repeat SequencesConceptsHealth Study cohortBreast cancer casesBreast cancerCancer casesNurses' Health Study cohortIncident breast cancer casesHRAS1 VNTRHRAS1 variable numberBreast cancer riskCase-control studyGene-dose effectRare HRAS1 allelesMenopausal statusStudy cohortCancer riskOverall associationCancerHRAS1 allelesRiskRare allelesAssociationCommon allelesAllelesVariable numberCohort
2002
Physical Activity, Body Mass Index, and Ovulatory Disorder Infertility
Rich-Edwards JW, Spiegelman D, Garland M, Hertzmark E, Hunter DJ, Colditz GA, Willett WC, Wand H, Manson JE. Physical Activity, Body Mass Index, and Ovulatory Disorder Infertility. Epidemiology 2002, 13: 184-190. PMID: 11880759, DOI: 10.1097/00001648-200203000-00013.Peer-Reviewed Original ResearchConceptsBody mass indexOvulatory disorder infertilityHealth Study IIOvulatory infertilityRelative riskMass indexVigorous activityNurses' Health Study IIVigorous-intensity exerciseLower relative riskAmerican womenAdiposity levelsIntensity exercisePhysical activitySedentary lifestyleBMI distributionInfertilityU.S. womenStudy IIWomenUnderweightRiskWeekly activitiesAssociationHours
2000
Polymorphic repeat in AIB1 does not alter breast cancer risk
Haiman C, Hankinson S, Spiegelman D, Colditz G, Willett W, Speizer F, Brown M, Hunter D. Polymorphic repeat in AIB1 does not alter breast cancer risk. Breast Cancer Research 2000, 2: 378. PMID: 11056690, PMCID: PMC13920, DOI: 10.1186/bcr82.Peer-Reviewed Original ResearchConceptsBreast cancer riskHealth Study cohortCancer riskPostmenopausal breast cancer riskNurses' Health Study cohortBreast cancer incidenceCase-control studySpecific tumor characteristicsAIB1 genotypeStudy cohortTumor characteristicsCancer incidenceCaucasian womenGeneral populationAIB1Repeat polymorphismRiskAssociationCohortIncidenceGenotypesWomen
1999
Prospective Study of Alcohol Consumption Patterns in Relation to Symptomatic Gallstone Disease in Men
Leitzmann M, Giovannucci E, Stampfer M, Spiegelman D, Colditz G, Willett W, Rimm E. Prospective Study of Alcohol Consumption Patterns in Relation to Symptomatic Gallstone Disease in Men. Alcohol Clinical And Experimental Research 1999, 23: 835-841. PMID: 10371403, DOI: 10.1111/j.1530-0277.1999.tb04191.x.Peer-Reviewed Original ResearchConceptsSymptomatic gallstone diseaseGallstone diseaseAlcohol intakeAlcohol consumption patternsDecreased riskAmount of alcoholAlcohol consumptionCohort of menAlcoholic beverage typesSymptomatic gallstonesFrequent intakeModerate intakeProspective studyRisk factorsSignificant associationDiseaseIntakeBeverage typePotential health hazardsRiskMenAlcoholic beveragesHealth hazardsAssociationConsumption patterns
1998
Retrospective Analysis of Birth Weight and Prostate Cancer in the Health Professionals Follow-up Study
Platz E, Giovannucci E, Rimm E, Curhan G, Spiegelman D, Colditz G, Willett W. Retrospective Analysis of Birth Weight and Prostate Cancer in the Health Professionals Follow-up Study. American Journal Of Epidemiology 1998, 147: 1140-1144. PMID: 9645792, DOI: 10.1093/oxfordjournals.aje.a009412.Peer-Reviewed Original ResearchConceptsHealth Professionals FollowBirth weightProstate cancerProfessionals FollowProstate cancer incidenceMultivariate logistic modelModest positive associationGrade tumorsProstatic cancerCancer incidenceRelative riskRetrospective analysisOverall associationCancerPositive associationFollowAssociationLogistic modelWeightTumorsIncidence
1997
Epidemiologic determinants of endometriosis: A hospital-based case-control study
Signorello L, Harlow B, Cramer D, Spiegelman D, Hill J. Epidemiologic determinants of endometriosis: A hospital-based case-control study. Annals Of Epidemiology 1997, 7: 267-274. PMID: 9177109, DOI: 10.1016/s1047-2797(97)00017-3.Peer-Reviewed Original ResearchConceptsCase-control studyControl groupHospital-based case-control studyInfertility-associated endometriosisBody mass indexConfidence intervalsPrimary control groupRisk of endometriosisEpidemiologic determinantsMenstrual characteristicsInfertile womenMass indexControl womenFertile womenInverse associationRisk factorsWomen's HospitalEndometriosisAlcohol consumptionAlternate control groupsWomenHospitalAssociationControl selectionSmoking
1988
CHOICE OF NON-STEROIDIAL ANTI-INFLAMMATORY DRUG IN PERSONS TREATED FOR DYSPEPSIA
Avila M, Walker A, Romieu I, Perera D, Spiegelman D, Jick H. CHOICE OF NON-STEROIDIAL ANTI-INFLAMMATORY DRUG IN PERSONS TREATED FOR DYSPEPSIA. The Lancet 1988, 332: 556-559. PMID: 2900932, DOI: 10.1016/s0140-6736(88)92670-0.Peer-Reviewed Original ResearchConceptsNon-steroidal anti-inflammatory drugsUlcer diseaseMost non-steroidal anti-inflammatory drugsElderly dyspeptic patientsUse of analgesicsGroup Health CooperativeUse of paracetamolAnti-inflammatory drugsAnalgesic useDyspeptic patientsHealth CooperativeInflammatory DrugsPrior useReported associationsCausal associationAnalgesicsCimetidineSimilar ageDrugsUlcersDiseaseAssociationAgeParacetamolPrior studies