2024
Estimating the lives that could be saved by expanded access to weight-loss drugs
Pandey A, Ye Y, Wells C, Singer B, Galvani A. Estimating the lives that could be saved by expanded access to weight-loss drugs. Proceedings Of The National Academy Of Sciences Of The United States Of America 2024, 121: e2412872121. PMID: 39405358, PMCID: PMC11513960, DOI: 10.1073/pnas.2412872121.Peer-Reviewed Original ResearchConceptsGlucagon-like peptide-1Body mass index categoriesObesity prevalence dataGlucagon-like peptide-1 receptor agonistsHazard ratio of mortalityRatio of mortalityPublic health impactWeight loss drugsInsurance coverage issuesGastric inhibitory polypeptideHealthcare accessType 2 diabetesUnited StatesPublic health crisisObesity epidemicReceptor agonistsIndex categoriesHazard ratioPrevalence dataInhibitory polypeptidePeptide-1Health impactsNovel treatmentObesityHealth crisisMortality and morbidity ramifications of proposed retractions in healthcare coverage for the United States
Pandey A, Fitzpatrick M, Singer B, Galvani A. Mortality and morbidity ramifications of proposed retractions in healthcare coverage for the United States. Proceedings Of The National Academy Of Sciences Of The United States Of America 2024, 121: e2321494121. PMID: 38648491, PMCID: PMC11066981, DOI: 10.1073/pnas.2321494121.Peer-Reviewed Original ResearchEvaluation of Strategies for Transitioning to Annual SARS-CoV-2 Vaccination Campaigns in the United States.
Wells C, Pandey A, Moghadas S, Fitzpatrick M, Singer B, Galvani A. Evaluation of Strategies for Transitioning to Annual SARS-CoV-2 Vaccination Campaigns in the United States. Annals Of Internal Medicine 2024, 177: 609-617. PMID: 38527289, DOI: 10.7326/m23-2451.Peer-Reviewed Original ResearchSARS-CoV-2 vaccination campaignSARS-CoV-2Centers for Disease Control and PreventionDisease Control and PreventionSARS-CoV-2 vaccinesHealth care costsVaccine-acquired immunityFood and Drug AdministrationU.S. Food and Drug AdministrationControl and PreventionNational Institutes of HealthVaccination campaignInfluenza vaccineInitial doseInstitutes of HealthSARS-CoV-2 variantsBooster doseImmune evasionDrug AdministrationUnited StatesNotsew Orm Sands FoundationDoseHealthPopulation immunityNational InstituteA Generalizable Theory-Driven Agent-Based Framework to Study Conflict-Induced Forced Migration
Mehrab Z, Stundal L, Venkatramanan S, Swarup S, Lewis B, Mortveit H, Barrett C, Pandey A, Wells C, Galvani A, Singer B, Moghadas S, Leblang D, Colwell R, Marathe M. A Generalizable Theory-Driven Agent-Based Framework to Study Conflict-Induced Forced Migration. Proceedings Of The AAAI Conference On Artificial Intelligence 2024, 38: 23027-23033. DOI: 10.1609/aaai.v38i21.30345.Peer-Reviewed Original ResearchAgent-based frameworkForced migrationGraph dynamical systemsPolicy implicationsConflict-induced migrationLarge-scale population displacementMigration outflowPolicy challengesComputational frameworkSpatial granularityPopulation displacementSocial theoryConflict settingsRussian forcesModeling frameworkCivilian populationSocial sciencesPolicyAn agent-based framework to study forced migration: A case study of Ukraine
Mehrab Z, Stundal L, Venkatramanan S, Swarup S, Lewis B, Mortveit H, Barrett C, Pandey A, Wells C, Galvani A, Singer B, Leblang D, Colwell R, Marathe M. An agent-based framework to study forced migration: A case study of Ukraine. PNAS Nexus 2024, 3: pgae080. PMID: 38505694, PMCID: PMC10949908, DOI: 10.1093/pnasnexus/pgae080.Peer-Reviewed Original ResearchForced migrationOutflow of migrantsCase study of UkraineStudy of UkraineDeliver humanitarian assistanceMigration flowsHumanitarian assistanceHumanitarian resourcesPolicy-makersConflict eventsPolicymaker uncertaintyPolicy questionsRussian aggressionCrisis settingsUkraine warConflictPolicyConflict scenariosUkraineCase studyMigrantsMigrationBehavioral theoryWarCrisis
2023
Modelling the impact of a high-uptake bivalent booster scenario on the COVID-19 burden and healthcare costs in New York City
Pandey A, Fitzpatrick M, Moghadas S, Vilches T, Ko C, Vasan A, Galvani A. Modelling the impact of a high-uptake bivalent booster scenario on the COVID-19 burden and healthcare costs in New York City. The Lancet Regional Health - Americas 2023, 24: 100555. PMID: 37554154, PMCID: PMC10405058, DOI: 10.1016/j.lana.2023.100555.Peer-Reviewed Original ResearchHealthcare costsVaccine dosesInfluenza vaccine coverageCOVID-19 illnessDirect healthcare costsSevere health outcomesCOVID-19 vaccineCOVID-19 burdenNew York CityBooster vaccineVaccine coverageVaccination ratesBivalent vaccineBase case scenarioHealth outcomesEligible residentsProbable casesDisease controlVaccineCanadian InstituteCOVID-19VaccinationHealth researchCommonwealth FundOutcomesEstimated US Pediatric Hospitalizations and School Absenteeism Associated With Accelerated COVID-19 Bivalent Booster Vaccination
Fitzpatrick M, Moghadas S, Vilches T, Shah A, Pandey A, Galvani A. Estimated US Pediatric Hospitalizations and School Absenteeism Associated With Accelerated COVID-19 Bivalent Booster Vaccination. JAMA Network Open 2023, 6: e2313586. PMID: 37204795, PMCID: PMC10199352, DOI: 10.1001/jamanetworkopen.2023.13586.Peer-Reviewed Original ResearchConceptsBooster campaignBooster vaccinationInfluenza vaccinationPediatric populationDecision analytical modelSchool absenteeismIntensive carePediatric hospitalizationsEligible individualsMAIN OUTCOMEAge groupsIntensive care unit admissionCare unit admissionSeasonal influenza vaccinationCOVID-19 illnessCOVID-19 prevention strategiesEligible age groupDecreased hospitalizationsUnit admissionCOVID-19 transmissionSymptomatic infectionAdverse outcomesIsolation daysHospitalizationGeneral populationExacerbation of measles mortality by vaccine hesitancy worldwide
Pandey A, Galvani A. Exacerbation of measles mortality by vaccine hesitancy worldwide. The Lancet Global Health 2023, 11: e478-e479. PMID: 36925157, DOI: 10.1016/s2214-109x(23)00063-3.Peer-Reviewed Original ResearchDisease burden among Ukrainians forcibly displaced by the 2022 Russian invasion
Pandey A, Wells C, Stadnytskyi V, Moghadas S, Marathe M, Sah P, Crystal W, Meyers L, Singer B, Nesterova O, Galvani A. Disease burden among Ukrainians forcibly displaced by the 2022 Russian invasion. Proceedings Of The National Academy Of Sciences Of The United States Of America 2023, 120: e2215424120. PMID: 36780515, PMCID: PMC9974407, DOI: 10.1073/pnas.2215424120.Peer-Reviewed Original Research
2022
Role of immunity landscape in global risk assessment of re-emerging diseases
Pandey A, Galvani A. Role of immunity landscape in global risk assessment of re-emerging diseases. The Lancet Infectious Diseases 2022, 23: 385-386. PMID: 36455592, PMCID: PMC9704845, DOI: 10.1016/s1473-3099(22)00756-3.Peer-Reviewed Original ResearchIs life expectancy higher in countries and territories with publicly funded health care? Global analysis of health care access and the social determinants of health
Galvani-Townsend S, Martinez I, Pandey A. Is life expectancy higher in countries and territories with publicly funded health care? Global analysis of health care access and the social determinants of health. Journal Of Global Health 2022, 12: 04091. PMID: 36370409, PMCID: PMC9653205, DOI: 10.7189/jogh.12.04091.Peer-Reviewed Original ResearchConceptsHealth care accessLevel of burdenCare accessSocial determinantsHealth careLife expectancyCountry-level informationMultiple social determinantsLonger life expectancyEconomic stabilityLongevity of lifeMean life expectancyEquitable distributionHealthy agingCareCountriesBurdenDeterminantsExpectancyDescriptive statistical analysisHealthSubstantial impactStatistical analysisQuartileReturn on Investment of the COVID-19 Vaccination Campaign in New York City
Sah P, Vilches T, Moghadas S, Pandey A, Gondi S, Schneider E, Singer J, Chokshi D, Galvani A. Return on Investment of the COVID-19 Vaccination Campaign in New York City. JAMA Network Open 2022, 5: e2243127. PMID: 36409495, PMCID: PMC9679875, DOI: 10.1001/jamanetworkopen.2022.43127.Peer-Reviewed Original ResearchConceptsCOVID-19 vaccination campaignVaccination campaignIntensive care unit admissionCare unit admissionEmergency department visitsIndirect costsDecision analytical modelEmergency medical servicesCOVID-19 deathsHealth care expendituresUnit admissionDepartment visitsFuture COVID-19 outbreaksNew York CityOutpatient visitsVaccine uptakeSevere outcomesVaccination programPotential yearsMAIN OUTCOMEVaccinationHealth outcomesProbable casesSocietal perspectiveCare expendituresQuarantine and serial testing for variants of SARS-CoV-2 with benefits of vaccination and boosting on consequent control of COVID-19
Wells CR, Pandey A, Gokcebel S, Krieger G, Donoghue AM, Singer BH, Moghadas SM, Galvani AP, Townsend JP. Quarantine and serial testing for variants of SARS-CoV-2 with benefits of vaccination and boosting on consequent control of COVID-19. PNAS Nexus 2022, 1: pgac100. PMID: 35909795, PMCID: PMC9335027, DOI: 10.1093/pnasnexus/pgac100.Peer-Reviewed Original ResearchSARS-CoV-2Serial testingSerial testing strategyHigh population immunityQuarantine durationBenefits of vaccinationSARS-CoV-2 variantsDisease time courseCOVID-19CoV-2 variantsPublic health toolVaccine boostingThird doseVaccination statusVaccination coveragePopulation immunityCoV-2Health toolsDisease control effortsInfected casesLocal transmissionInfectiousness profileVaccinationTime courseImmunityUniversal healthcare as pandemic preparedness: The lives and costs that could have been saved during the COVID-19 pandemic
Galvani AP, Parpia AS, Pandey A, Sah P, Colón K, Friedman G, Campbell T, Kahn JG, Singer BH, Fitzpatrick MC. Universal healthcare as pandemic preparedness: The lives and costs that could have been saved during the COVID-19 pandemic. Proceedings Of The National Academy Of Sciences Of The United States Of America 2022, 119: e2200536119. PMID: 35696578, PMCID: PMC9231482, DOI: 10.1073/pnas.2200536119.Peer-Reviewed Original ResearchModeling comparative cost-effectiveness of SARS-CoV-2 vaccine dose fractionation in India
Du Z, Wang L, Pandey A, Lim WW, Chinazzi M, Piontti APY, Lau EHY, Wu P, Malani A, Cobey S, Cowling BJ. Modeling comparative cost-effectiveness of SARS-CoV-2 vaccine dose fractionation in India. Nature Medicine 2022, 28: 934-938. PMID: 35210596, PMCID: PMC9117137, DOI: 10.1038/s41591-022-01736-z.Peer-Reviewed Original ResearchConceptsLarge-scale survey dataEconomic benefitsFull dose vaccinationSurvey dataHospital admission costsDose-sparing strategiesCost of hospitalizationCOVID-19 deathsPopulation-level transmissionVaccine dosesVaccination strategiesAdmission costsEconomic burdenVaccine shortageFractional dosesVaccinationDose fractionationHigh transmissibilityVaccine distributionCostPublic healthVaccineWillingnessDosesIndiaQuarantine and testing strategies to ameliorate transmission due to travel during the COVID-19 pandemic: a modelling study
Wells CR, Pandey A, Fitzpatrick MC, Crystal WS, Singer BH, Moghadas SM, Galvani AP, Townsend JP. Quarantine and testing strategies to ameliorate transmission due to travel during the COVID-19 pandemic: a modelling study. The Lancet Regional Health - Europe 2022, 14: 100304. PMID: 35036981, PMCID: PMC8743228, DOI: 10.1016/j.lanepe.2021.100304.Peer-Reviewed Original ResearchShorter quarantineContacts of casesQuarantine durationCOVID-19 infectionLarge socioeconomic burdenCOVID-19 pandemicRisk stratificationSocioeconomic burdenInfection rateRT-PCRThree daysCanadian InstitutePandemic diseaseNational InstituteHealth researchLonger quarantineEpidemic situationTesting strategies
2021
Challenges facing COVID-19 vaccination in India: Lessons from the initial vaccine rollout
Pandey A, Sah P, Moghadas SM, Mandal S, Banerjee S, Hotez PJ, Galvani AP. Challenges facing COVID-19 vaccination in India: Lessons from the initial vaccine rollout. Journal Of Global Health 2021, 11: 03083. PMID: 34221355, PMCID: PMC8243816, DOI: 10.7189/jogh.11.03083.Peer-Reviewed Original ResearchRole of the G20 in safe reopening of international travel
Pandey A, Galvani AP. Role of the G20 in safe reopening of international travel. The Lancet Infectious Diseases 2021, 21: 919. PMID: 34174233, DOI: 10.1016/s1473-3099(21)00341-8.Peer-Reviewed Original ResearchRacial disparities in COVID-19 mortality across Michigan, United States
Parpia AS, Martinez I, El-Sayed AM, Wells CR, Myers L, Duncan J, Collins J, Fitzpatrick MC, Galvani AP, Pandey A. Racial disparities in COVID-19 mortality across Michigan, United States. EClinicalMedicine 2021, 33: 100761. PMID: 33718849, PMCID: PMC7933264, DOI: 10.1016/j.eclinm.2021.100761.Peer-Reviewed Original ResearchCOVID-19 mortalityNumber of comorbiditiesMortality rateComorbidity prevalenceHealth characteristicsBlack individualsCOVID-19White counterpartsBlack populationMortality burdenDeath certificatesMortality riskHigh riskComorbiditiesSurveillance dataMortalityRacial disparitiesWhite individualsDemographic characteristicsCharacteristics of individualsCOVID-19 pandemicAgeSexPrevalenceHuman ServicesComparative cost-effectiveness of SARS-CoV-2 testing strategies in the USA: a modelling study
Du Z, Pandey A, Bai Y, Fitzpatrick MC, Chinazzi M, Pastore Y Piontti A, Lachmann M, Vespignani A, Cowling BJ, Galvani AP, Meyers LA. Comparative cost-effectiveness of SARS-CoV-2 testing strategies in the USA: a modelling study. The Lancet Public Health 2021, 6: e184-e191. PMID: 33549196, PMCID: PMC7862022, DOI: 10.1016/s2468-2667(21)00002-5.Peer-Reviewed Original ResearchConceptsLow transmission scenarioSARS-CoV-2 testing programSevere acute respiratory syndrome coronavirus 2Acute respiratory syndrome coronavirus 2Respiratory syndrome coronavirus 2SARS-CoV-2 transmissionSymptom-based testingSyndrome coronavirus 2Viral load dynamicsYLL avertedSARS-CoV-2 testing strategyTesting strategiesPositive test resultsCOVID-19 pandemicYears of lifeIsolation periodCoronavirus 2US National InstitutesViral testingPhysical distancing measuresEfficacious vaccineUS CentersAntiviral drugsIsolation durationEffective reproduction number