2024
Impact of a community health worker led intervention for improved blood pressure control in urban Nepal: an open-label cluster randomised controlled trial
Bhattarai S, Skovlund E, Shrestha A, Mjølstad B, Åsvold B, Sen A. Impact of a community health worker led intervention for improved blood pressure control in urban Nepal: an open-label cluster randomised controlled trial. The Lancet Regional Health - Southeast Asia 2024, 29: 100461. PMID: 39220804, PMCID: PMC11364134, DOI: 10.1016/j.lansea.2024.100461.Peer-Reviewed Original ResearchCommunity health workersIntervention arm compared to controlsWaist-to-hip ratioHealth workersRandomised controlled trialsBody mass indexPhysical activityDaily salt intakeHealthcare providersSystolic blood pressureDiastolic blood pressureCluster randomised controlled trialOpen-label cluster randomised controlled trialRoutine follow-up careMass indexHealth system barriersAdequate physical activityControlled trialsTrained healthcare providersDiet quality scoresBlood pressure controlPublic health facilitiesInterventions targeting individualsUrban NepalControl blood pressure
2020
Cardiovascular disease trends in Nepal – An analysis of global burden of disease data 2017
Bhattarai S, Aryal A, Pyakurel M, Bajracharya S, Baral P, Citrin D, Cox H, Dhimal M, Fitzpatrick A, Jha AK, Jha N, Karmacharya BM, Koju R, Maharjan R, Oli N, Pyakurel P, Sapkota BP, Shrestha R, Shrestha S, Spiegelman D, Vaidya A, Shrestha A. Cardiovascular disease trends in Nepal – An analysis of global burden of disease data 2017. IJC Heart & Vasculature 2020, 30: 100602. PMID: 32775605, PMCID: PMC7399110, DOI: 10.1016/j.ijcha.2020.100602.Peer-Reviewed Original ResearchBurden of CVDCardiovascular diseaseGlobal burdenBlood pressureTotal DALYsRisk factorsDiet lowTotal deathsHigh low-density lipoprotein cholesterolHigher systolic blood pressureLow-density lipoprotein cholesterolMajor public health problemCardiovascular disease trendsPredominant cardiovascular diseasesCardiovascular disease incidenceDensity lipoprotein cholesterolSystolic blood pressureHigh blood pressureIschemic heart diseaseBody mass indexEvaluation's Global BurdenPublic health problemOlder age groupsLipoprotein cholesterolMiddle-income countries
2019
Socio-economic inequalities in hypertension burden and cascade of services: nationwide cross-sectional study in Nepal
Mishra SR, Ghimire S, Shrestha N, Shrestha A, Virani SS. Socio-economic inequalities in hypertension burden and cascade of services: nationwide cross-sectional study in Nepal. Journal Of Human Hypertension 2019, 33: 613-625. PMID: 30659279, DOI: 10.1038/s41371-019-0165-3.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedBlood PressureCross-Sectional StudiesEducational StatusFemaleHealth Knowledge, Attitudes, PracticeHealth Services AccessibilityHealth Status DisparitiesHealthcare DisparitiesHumansHypertensionIncomeMaleMiddle AgedNepalPrevalenceResidence CharacteristicsRisk AssessmentRisk FactorsSocial Determinants of HealthYoung AdultConceptsCascade of servicesNationwide cross-sectional studyPrevalence of hypertensionControl of hypertensionBody mass indexMulti-variable logistic regressionTreatment of hypertensionCross-sectional studyNepal Demographic Health SurveyLowest wealth quintileSocio-economic inequalitiesDemographic Health SurveyHousehold wealth statusHypertension burdenTotal hypertensivesHypertensive femalesHypertension awarenessHypertension prevalenceBlood pressureMass indexHypertension statusDisease burdenHealth SurveyHypertensionCoverage of services
2017
Awareness, Prevalence, Treatment, and Control of Hypertension in Western Nepal
Neupane D, Shrestha A, Mishra SR, Bloch J, Christensen B, McLachlan CS, Karki A, Kallestrup P. Awareness, Prevalence, Treatment, and Control of Hypertension in Western Nepal. American Journal Of Hypertension 2017, 30: 907-913. PMID: 28531244, DOI: 10.1093/ajh/hpx074.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntihypertensive AgentsAwarenessBlood PressureChi-Square DistributionCross-Sectional StudiesFemaleHealth Care SurveysHealth Knowledge, Attitudes, PracticeHumansHypertensionLife StyleLogistic ModelsMaleMiddle AgedMultivariate AnalysisNepalOdds RatioPrevalenceRisk FactorsRisk Reduction BehaviorSuburban HealthTreatment OutcomeConceptsControl of hypertensionBlood pressureRisk factorsHigher body mass indexBP control targetsPrevalence of hypertensionModifiable risk factorsSex-adjusted prevalenceDiastolic blood pressureLow physical activitySystolic blood pressureBody mass indexHarmful alcohol intakeHarmful alcohol drinkersCross-sectional surveyLow-income settingsSemi-urban settingHypertension burdenHypertensive medicationsPreexisting hypertensionHypertensive participantsAntihypertensive medicinesRenal diseaseMass indexAlcohol drinkersAwareness, treatment and control of hypertension in Nepal: findings from the Dhulikhel Heart Study
Karmacharya BM, Koju RP, LoGerfo JP, Chan KC, Mokdad AH, Shrestha A, Sotoodehnia N, Fitzpatrick AL. Awareness, treatment and control of hypertension in Nepal: findings from the Dhulikhel Heart Study. Heart Asia 2017, 9: 1. PMID: 28123454, PMCID: PMC5237714, DOI: 10.1136/heartasia-2016-010766.Peer-Reviewed Original ResearchControl of hypertensionDhulikhel Heart StudyCross-sectional studyHypertension awarenessHypertension statusRisk factorsHeart StudySociodemographic characteristicsCardiovascular disease risk factorsCVD risk factorsPrevalence of hypertensionBlood pressure controlDisease risk factorsBody mass indexBlood pressure measurementsHypertensive adultsMass indexHealth InterviewMultivariate regression modelHypertensionTreatment statusNepalese adultsMultivariate analysisPressure controlIncome quartileDetermining the Prevalence of and Risk Factors for Depressive Symptoms among Adults in Nepal.
Lam MS, Fitzpatrick AL, Shrestha A, Karmacharya BM, Koju R, Rao D. Determining the Prevalence of and Risk Factors for Depressive Symptoms among Adults in Nepal. International Journal Of Noncommunicable Diseases 2017, 2: 18-26. PMID: 30574570, PMCID: PMC6298440, DOI: 10.4103/jncd.jncd_34_16.Peer-Reviewed Original ResearchNon-communicable diseasesDhulikhel Heart StudyBody mass indexRisk factorsDepressive symptomsChi-squared testAdults age 18 yearsCardiovascular risk factorsEpidemiologic Studies Depression ScalePrevalence of depressionSignificant risk factorsLongitudinal cohort studyBaseline questionnaire dataMultiple logistic regressionAge 18 yearsPearson's chi-squared testMajor depressive symptomatologyCross-sectional analysisCESD scoresCohort studyMass indexHypertensive statusPhysical inactivityDepression ScalePhysical activityPrevalence and Correlates of Tobacco Use in a Suburban community of Nepal: Findings from the Dhulikhel Heart Study.
Karmacharya B, Shrestha A, Fitzpatrick AL, Koju R, Sotodehnia N, Xu DR. Prevalence and Correlates of Tobacco Use in a Suburban community of Nepal: Findings from the Dhulikhel Heart Study. Kathmandu University Medical Journal 2017, 15: 336-342. PMID: 30580353.Peer-Reviewed Original ResearchConceptsDhulikhel Heart StudyOral tobacco useOral tobaccoTobacco useBrahmin/ChhetriCurrent smokersRisk factorsHeart StudyTobacco consumptionAdults age 18 yearsCVD risk factorsPrevalence of smokingBody mass indexImportant risk factorAge 18 yearsOdds of smokingSuburban populationBackground SmokingMass indexSectional studyChronic diseasesEpidemiological aspectsModerate drinkersAlcohol consumptionHigh drinkers
2016
Food patterns measured by principal component analysis and obesity in the Nepalese adult
Shrestha A, Koju RP, Beresford SA, Chan K, Karmacharya BM, Fitzpatrick AL. Food patterns measured by principal component analysis and obesity in the Nepalese adult. Heart Asia 2016, 8: 46. PMID: 27326232, PMCID: PMC4898623, DOI: 10.1136/heartasia-2015-010666.Peer-Reviewed Original ResearchBody mass indexRisk factorsDietary patternsNepalese adultsHigh prevalenceFood patternsTraditional cardiovascular risk factorsDhulikhel Heart StudyFast food patternCardiovascular risk factorsMajor dietary patternsFood frequency questionnaireSystolic blood pressureTraditional risk factorsMultivariate logistic regressionFast food intakeCross-sectional studyFrequency questionnaireBlood pressureMass indexAlcohol intakeObesity prevalenceFood intakePhysical activityHeart Study