2023
Exposure to per- and polyfluoroalkyl substances in early pregnancy and risk of cerebral palsy in children
Vilhelmsson A, Rylander L, Jöud A, Lindh C, Mattsson K, Liew Z, Guo P, Ritz B, Källén K, Thacher J. Exposure to per- and polyfluoroalkyl substances in early pregnancy and risk of cerebral palsy in children. The Science Of The Total Environment 2023, 899: 165622. PMID: 37474063, DOI: 10.1016/j.scitotenv.2023.165622.Peer-Reviewed Original ResearchConceptsOdds ratioPreterm infantsEarly pregnancyPerfluorononanoic acidPrenatal PFAS exposureMaternal serum concentrationsCerebral palsy casesConfidence intervalsCase-control studyRisk of CPEnvironmental risk factorsPositive associationContinuous variablesHigh PFASPalsy casesBirth RegistryPreterm controlsCerebral palsyLifestyle factorsPreterm casesUnexplained etiologyPrenatal exposureSerum concentrationsRisk factorsPerfluorooctane sulfonate
2016
Prenatal maternal bereavement and mortality in the first decades of life: a nationwide cohort study from Denmark and Sweden
Yu Y, Cnattingius S, Olsen J, Parner E, Vestergaard M, Liew Z, Zhao N, Li J. Prenatal maternal bereavement and mortality in the first decades of life: a nationwide cohort study from Denmark and Sweden. Psychological Medicine 2016, 47: 389-400. PMID: 27762181, DOI: 10.1017/s003329171600266x.Peer-Reviewed Original ResearchConceptsPrenatal maternal bereavementMaternal bereavementMortality riskCohort studyIncreased long-term mortality riskPopulation-based cohort studyLong-term mortality riskNationwide cohort studyLong-term mortalityCause mortality riskExcess mortality riskChildren of mothersFetal programming hypothesisYears of ageYears of lifeEndocrine/Stressful life eventsFetal deathSingleton birthsMedical conditionsProgramming hypothesisHigh riskUnnatural causesCongenital malformationsPrenatal stress
2015
Maternal use of acetaminophen during pregnancy and risk of autism spectrum disorders in childhood: A Danish national birth cohort study
Liew Z, Ritz B, Virk J, Olsen J. Maternal use of acetaminophen during pregnancy and risk of autism spectrum disorders in childhood: A Danish national birth cohort study. Autism Research 2015, 9: 951-958. PMID: 26688372, DOI: 10.1002/aur.1591.Peer-Reviewed Original ResearchMeSH KeywordsAcetaminophenAdultAttention Deficit Disorder with HyperactivityAutism Spectrum DisorderChildChild, PreschoolCohort StudiesComorbidityDenmarkFemaleHumansInfantInfant, NewbornMalePregnancyPrenatal Exposure Delayed EffectsProportional Hazards ModelsProspective StudiesRiskStatistics as TopicConceptsRisk of ASDHyperkinetic symptomsAcetaminophen useHazard ratioDanish National Birth CohortCox proportional hazards modelHyperactive behavioral phenotypesAutism spectrum disorderEnd of followNational Birth CohortComputer-assisted telephone interviewsProportional hazards modelInfantile autismConfident intervalFever medicationPsychiatric RegistryPrenatal useProspective dataMaternal useHyperkinetic disorderAcetaminophen exposureFetal lifeHazards modelDiagnosis of ASDBirth cohort
2014
Acetaminophen Use During Pregnancy, Behavioral Problems, and Hyperkinetic Disorders
Liew Z, Ritz B, Rebordosa C, Lee PC, Olsen J. Acetaminophen Use During Pregnancy, Behavioral Problems, and Hyperkinetic Disorders. JAMA Pediatrics 2014, 168: 313-320. PMID: 24566677, DOI: 10.1001/jamapediatrics.2013.4914.Peer-Reviewed Original ResearchMeSH KeywordsAcetaminophenAdultAttention Deficit Disorder with HyperactivityChildChild, PreschoolDenmarkFemaleHumansHyperkinesisInfantMaleMental DisordersMothersPregnancyPrenatal Exposure Delayed EffectsProportional Hazards ModelsProspective StudiesRisk AssessmentRisk FactorsSurveys and QuestionnairesConceptsAcetaminophen useHyperkinetic disorderADHD-like behaviorsMental health problemsPrenatal exposureADHD medicationHigh riskDanish National Hospital RegistryDanish Psychiatric Central RegistryDanish National Birth CohortBehavioral problemsMothers' mental health problemsDanish Prescription RegistryMaternal acetaminophen useNational Hospital RegistryNational Birth CohortExposure-response trendsComputer-assisted telephone interviewsFetal brain developmentAge 7 yearsChildren 7 yearsAttention-deficit/hyperactivity disorderPublic health relevanceADHD prescriptionsMaternal inflammation