2023
Hyperthyroidism in Danish Pregnant Women During a 20-Year Period
Torp N, Liew Z, Carlé A, Karmisholt J, Pedersen I, Andersen S, Andersen S. Hyperthyroidism in Danish Pregnant Women During a 20-Year Period. The Journal Of Clinical Endocrinology & Metabolism 2023, 109: e370-e378. PMID: 37437100, DOI: 10.1210/clinem/dgad410.Peer-Reviewed Original ResearchConceptsDanish pregnant womenOccurrence of hyperthyroidismAntithyroid drugsPregnant womenBiochemical hyperthyroidismMandatory iodine fortification programmeNationwide register-based cohortUse of ATDsRegister-based cohortIodine fortification programGeneral Danish populationNationwide cohortAutoimmune hyperthyroidismMaternal useOdds ratioTime-related differencesHyperthyroidismBirth cohortClinical concernBaseline levelsDanish populationFortification programsPregnancyCohortYoung individuals
2019
Perfluoroalkyl Substances and thyroid hormones in early pregnancy; findings in the Danish National Birth Cohort (DNBC)
Z L, K I, B R, S A, C R, B H, B B, T H, E B, J O. Perfluoroalkyl Substances and thyroid hormones in early pregnancy; findings in the Danish National Birth Cohort (DNBC). Environmental Epidemiology 2019, 3: 240-240. DOI: 10.1097/01.ee9.0000608512.83637.07.Peer-Reviewed Original Research
2018
Prenatal Exposure to Perfluoroalkyl Substances and Birth Outcomes; An Updated Analysis from the Danish National Birth Cohort
Meng Q, Inoue K, Ritz B, Olsen J, Liew Z. Prenatal Exposure to Perfluoroalkyl Substances and Birth Outcomes; An Updated Analysis from the Danish National Birth Cohort. International Journal Of Environmental Research And Public Health 2018, 15: 1832. PMID: 30149566, PMCID: PMC6164159, DOI: 10.3390/ijerph15091832.Peer-Reviewed Original ResearchConceptsDanish National Birth CohortLow birth weightNational Birth CohortBirth weightPreterm birthBirth outcomesPFASs exposureBirth cohortPrenatal PFASs exposureMaternal plasma concentrationsAdverse birth outcomesPerfluorononanoic acidPerfluorodecanoic acidWidespread industrial pollutantsPerfluoroalkyl substancesPerfluorooctanoate exposureGestational ageHighest quartileInfant pairsEarly pregnancyFetal growthPrenatal exposurePerfluoroheptane sulfonatePlasma concentrationsElevated riskPrenatal Exposure to Perfluoroalkyl Substances and IQ Scores at Age 5; a Study in the Danish National Birth Cohort
Liew Z, Ritz B, Bach CC, Asarnow RF, Bech BH, Nohr EA, Bossi R, Henriksen TB, Bonefeld-Jørgensen EC, Olsen J. Prenatal Exposure to Perfluoroalkyl Substances and IQ Scores at Age 5; a Study in the Danish National Birth Cohort. Environmental Health Perspectives 2018, 126: 067004. PMID: 29897723, PMCID: PMC6084884, DOI: 10.1289/ehp2754.Peer-Reviewed Original ResearchHow to investigate and adjust for selection bias in cohort studies
Nohr EA, Liew Z. How to investigate and adjust for selection bias in cohort studies. Acta Obstetricia Et Gynecologica Scandinavica 2018, 97: 407-416. PMID: 29415329, DOI: 10.1111/aogs.13319.Peer-Reviewed Original ResearchConceptsCohort studyDanish National Birth CohortSelection biasLong-term followNational Birth CohortLongitudinal cohort studyCase-control studySubsequent follow upsExposure-outcome associationsTraditional epidemiological approachesPreventable causeFollow-upInverse probability weightingBirth cohortInitial participation rateStudy designEpidemiological approachLimited dataCohortDiseaseBias analysisProbability weightingParticipation ratesParticipantsLess disease
2015
Maternal use of acetaminophen during pregnancy and risk of autism spectrum disorders in childhood: A Danish national birth cohort study
Liew Z, Ritz B, Virk J, Olsen J. Maternal use of acetaminophen during pregnancy and risk of autism spectrum disorders in childhood: A Danish national birth cohort study. Autism Research 2015, 9: 951-958. PMID: 26688372, DOI: 10.1002/aur.1591.Peer-Reviewed Original ResearchMeSH KeywordsAcetaminophenAdultAttention Deficit Disorder with HyperactivityAutism Spectrum DisorderChildChild, PreschoolCohort StudiesComorbidityDenmarkFemaleHumansInfantInfant, NewbornMalePregnancyPrenatal Exposure Delayed EffectsProportional Hazards ModelsProspective StudiesRiskStatistics as TopicConceptsRisk of ASDHyperkinetic symptomsAcetaminophen useHazard ratioDanish National Birth CohortCox proportional hazards modelHyperactive behavioral phenotypesAutism spectrum disorderEnd of followNational Birth CohortComputer-assisted telephone interviewsProportional hazards modelInfantile autismConfident intervalFever medicationPsychiatric RegistryPrenatal useProspective dataMaternal useHyperkinetic disorderAcetaminophen exposureFetal lifeHazards modelDiagnosis of ASDBirth cohortBias from conditioning on live birth in pregnancy cohorts: an illustration based on neurodevelopment in children after prenatal exposure to organic pollutants
Liew Z, Olsen J, Cui X, Ritz B, Arah OA. Bias from conditioning on live birth in pregnancy cohorts: an illustration based on neurodevelopment in children after prenatal exposure to organic pollutants. International Journal Of Epidemiology 2015, 44: 345-354. PMID: 25604449, PMCID: PMC4339763, DOI: 10.1093/ije/dyu249.Peer-Reviewed Original ResearchConceptsAttention-deficit/hyperactivity disorderLive birthsPrenatal exposurePregnancy cohortFetal lossDanish National Birth CohortLong-term health outcomesNational Birth CohortWeak inverse associationEarly fetal lossPerfluoroalkyl substancesPregnancy lossSchool-aged childrenInverse associationFetal survivalCommon causeObservational studyBirth cohortHealth outcomesHuman fecundityCohortHyperactivity disorderBirthOutcomesNeurodevelopment
2014
Attention Deficit/Hyperactivity Disorder and Childhood Autism in Association with Prenatal Exposure to Perfluoroalkyl Substances: A Nested Case–Control Study in the Danish National Birth Cohort
Liew Z, Ritz B, von Ehrenstein OS, Bech BH, Nohr EA, Fei C, Bossi R, Henriksen TB, Bonefeld-Jørgensen EC, Olsen J. Attention Deficit/Hyperactivity Disorder and Childhood Autism in Association with Prenatal Exposure to Perfluoroalkyl Substances: A Nested Case–Control Study in the Danish National Birth Cohort. Environmental Health Perspectives 2014, 123: 367-373. PMID: 25616253, PMCID: PMC4383573, DOI: 10.1289/ehp.1408412.Peer-Reviewed Original ResearchConceptsAttention-deficit/hyperactivity disorderDanish National Birth CohortNational Birth CohortDeficit/hyperactivity disorderPrenatal exposureRisk ratioChildhood autismBirth cohortDanish National Hospital RegistryDanish Psychiatric Central RegistryNested Case-Control StudyRisk of ADHDNational Hospital RegistryPrenatal PFAS exposureHyperactivity disorderCase-control studyMother-child pairsPerfluoroalkyl substancesConsistent evidenceHospital registryProspective studyPlasma levelsNeurobehavioral problemsPFAS exposureCentral RegistryPrenatal Exposure to Perfluoroalkyl Substances and the Risk of Congenital Cerebral Palsy in Children
Liew Z, Ritz B, Bonefeld-Jørgensen EC, Henriksen TB, Nohr EA, Bech BH, Fei C, Bossi R, von Ehrenstein OS, Streja E, Uldall P, Olsen J. Prenatal Exposure to Perfluoroalkyl Substances and the Risk of Congenital Cerebral Palsy in Children. American Journal Of Epidemiology 2014, 180: 574-581. PMID: 25139206, DOI: 10.1093/aje/kwu179.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlkanesulfonic AcidsCaprylatesCase-Control StudiesCerebral PalsyCohort StudiesDenmarkEndocrine DisruptorsEnvironmental MonitoringEnvironmental PollutantsFemaleFluorocarbonsHumansInfant, NewbornMaleMaternal AgeOdds RatioPregnancyPrenatal Exposure Delayed EffectsSex DistributionSex FactorsYoung AdultConceptsCongenital cerebral palsyPrenatal exposureCerebral palsyDanish National Birth CohortCerebral Palsy RegisterNational Birth CohortFetal brain developmentDose-response patternCase-cohort designPerfluoroalkyl substancesLiveborn singletonsMaternal levelsRisk ratioHigh riskCP casesCP riskBirth cohortMaternal plasmaBrain developmentPalsyPerfluorooctane sulfonateRiskPFAS levelsCohortPerfluorooctanoic acid