Bayesian subtyping for multi-state brain functional connectome with application on preadolescent brain cognition
Chen T, Zhao H, Tan C, Constable T, Yip S, Zhao Y. Bayesian subtyping for multi-state brain functional connectome with application on preadolescent brain cognition. Biostatistics 2024, kxae045. PMID: 39656842, DOI: 10.1093/biostatistics/kxae045.Peer-Reviewed Original ResearchAdolescent Brain Cognitive DevelopmentVariational inference algorithmApproximate posterior inferenceFunctional connectivityMultiple cognitive statesInference algorithmExtensive simulationsNetwork topologyNetwork featuresFunctional network patternsBrain functional connectomeBrain functional connectivityEstimation accuracySubgroups of individualsNeurobiological heterogeneityCognitive profileCognitive statesConverging evidencePosterior inferenceDetection alternativesNeuroscience literatureBrain cognitionFunctional connectomeNetworkCognitive developmentHeritability and genetic contribution analysis of structural-functional coupling in human brain
Dai W, Zhang Z, Song P, Zhang H, Zhao Y. Heritability and genetic contribution analysis of structural-functional coupling in human brain. Imaging Neuroscience 2024, 2: 1-19. DOI: 10.1162/imag_a_00346.Peer-Reviewed Original ResearchSC-FCSC-FC couplingStructural connectivityHuman Connectome ProjectConnectome ProjectVisual cortexCouplingFunctional connectivityWhite matter structural connectivityCingulo-opercularDorsal attentionGenetic correlation analysisSpectrum of complex traitsAdolescent Brain Cognitive Development StudyFunctional networksComplex traitsGenetic lociCognitive Development StudyGenetic variationGenetic interplayMode networkStructural-functional couplingSpectraMedial amygdalar tau is associated with mood symptoms in preclinical Alzheimer’s disease
Li J, Tun S, Ficek-Tani B, Xu W, Wang S, Horien C, Toyonaga T, Nuli S, Zeiss C, Powers A, Zhao Y, Mormino E, Fredericks C. Medial amygdalar tau is associated with mood symptoms in preclinical Alzheimer’s disease. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2024 PMID: 39059466, DOI: 10.1016/j.bpsc.2024.07.012.Peer-Reviewed Original ResearchAssociated with mood symptomsMood symptomsAmyloid-positive individualsMedial amygdalaSeed-based functional connectivity analysisAssociated with anxiety symptomsSelf-reported mood symptomsPost hoc correlation analysisAlzheimer's diseaseFunctional connectivity analysisPreclinical Alzheimer's diseaseTau bindingOrbitofrontal cortexTau depositionAmygdalar connectivityEmotional processingAnxiety symptomsRetrosplenial cortexBetween-group differencesAmygdalaFunctional connectivityLateral amygdalaConnectivity analysisDepression scoresNeuropsychiatric symptomsHomological Landscape of Human Brain Functional Sub-Circuits
Duong-Tran D, Kaufmann R, Chen J, Wang X, Garai S, Xu F, Bao J, Amico E, Kaplan A, Petri G, Goni J, Zhao Y, Shen L. Homological Landscape of Human Brain Functional Sub-Circuits. Mathematics 2024, 12: 455. DOI: 10.3390/math12030455.Peer-Reviewed Original ResearchFunctional sub-circuitsHuman brain functional connectivityWhole-brain functional connectivity networksNon-local propertiesWorking memory taskWhole-brain levelBrain functional connectivityNon-localFunctional connectivity networksMemory taskEmotional tasksLimbic networkMode networkFunctional connectivityBrain connectomeWhole-brainFormalismLocal structureMotor tasksConnectivity networksSubject domainSub-circuitsTask