2021
Semiquantitative Real-Time PCR to Distinguish Pneumocystis Pneumonia from Colonization in a Heterogeneous Population of HIV-Negative Immunocompromised Patients
Grønseth S, Rogne T, Hannula R, Åsvold BO, Afset JE, Damås JK. Semiquantitative Real-Time PCR to Distinguish Pneumocystis Pneumonia from Colonization in a Heterogeneous Population of HIV-Negative Immunocompromised Patients. Microbiology Spectrum 2021, 9: 10.1128/spectrum.00026-21. PMID: 34346746, PMCID: PMC8552647, DOI: 10.1128/spectrum.00026-21.Peer-Reviewed Original ResearchConceptsSemiquantitative real-time PCRPneumocystis pneumoniaReal-time PCRCutoff valuePCP statusHigher fungal loadHematological malignanciesPneumocystis jiroveciiHIV-negative immunocompromised patientsHuman immunodeficiency virus (HIV) infectionLower respiratory tract specimensRisk of PCPSolid organ transplant recipientsFungal loadHIV Pneumocystis pneumoniaImmunodeficiency virus infectionOrgan transplant recipientsSolid organ recipientsHIV-negative individualsPCR-positive patientsSolid organ transplantationRespiratory tract specimensVulnerable patient populationLife-threatening infectionsAcute respiratory syndromeEpidemiological and clinical characteristics of immunocompromised patients infected with Pneumocystis jirovecii in a twelve-year retrospective study from Norway
Grønseth S, Rogne T, Hannula R, Åsvold BO, Afset JE, Damås JK. Epidemiological and clinical characteristics of immunocompromised patients infected with Pneumocystis jirovecii in a twelve-year retrospective study from Norway. BMC Infectious Diseases 2021, 21: 659. PMID: 34233631, PMCID: PMC8262122, DOI: 10.1186/s12879-021-06144-1.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusRegional incidence ratesRetrospective studyMedical recordsIncidence rateP. jiroveciiTwelve-year retrospective studyMain clinical findingsMajor risk factorPatients' medical recordsHospital mortalityImmunosuppressant usePCP prophylaxisClinical characteristicsMost patientsRadiological featuresPerson yearsClinical findingsImmunodeficiency virusIntensive carePolymerase chain reactionRisk factorsModern chemotherapyCardinal symptomsStudy populationGWAS Identifies LINC01184/SLC12A2 as a Risk Locus for Skin and Soft Tissue Infections
Rogne T, Liyanarachi KV, Rasheed H, Thomas LF, Flatby HM, Stenvik J, Løset M, Gill D, Burgess S, Willer CJ, Hveem K, Åsvold BO, Brumpton BM, DeWan AT, Solligård E, Damås JK. GWAS Identifies LINC01184/SLC12A2 as a Risk Locus for Skin and Soft Tissue Infections. Journal Of Investigative Dermatology 2021, 141: 2083-2086.e8. PMID: 33662382, PMCID: PMC7612997, DOI: 10.1016/j.jid.2021.01.020.Peer-Reviewed Original Research
2020
Genome-Wide Linkage Analysis of the Risk of Contracting a Bloodstream Infection in 47 Pedigrees Followed for 23 Years Assembled From a Population-Based Cohort (the HUNT Study).
Rogne T, Damås JK, Solligård E, DeWan AT. Genome-Wide Linkage Analysis of the Risk of Contracting a Bloodstream Infection in 47 Pedigrees Followed for 23 Years Assembled From a Population-Based Cohort (the HUNT Study). Critical Care Medicine 2020, 48: 1580-1586. PMID: 32885941, DOI: 10.1097/ccm.0000000000004520.Peer-Reviewed Original Research
2019
Presenting complaints and mortality in a cohort of 22 000 adult emergency patients at a local hospital in Nepal
Giri S, Rogne T, Uleberg O, Skovlund E, Shrestha SK, Koju R, Damås JK, Solligård E, Risnes KR. Presenting complaints and mortality in a cohort of 22 000 adult emergency patients at a local hospital in Nepal. Journal Of Global Health 2019, 9: 020403. PMID: 31489186, PMCID: PMC6708590, DOI: 10.7189/jogh.09.020403.Peer-Reviewed Original ResearchConceptsLow-resource settingsEmergency departmentAdult emergency patientsPost-discharge mortalityChronic lung diseaseEmergency department populationHealth carePrimary health careEmergency health care systemHealth care needsPost-discharge studyHealth care systemEmergency health careAbdominal complaintsED dischargeAdult patientsMedian ageLung diseaseAppropriate followSex distributionEmergency patientsLocal hospitalCare needsPatientsHigh mortality
2018
Rate of avoidable deaths in a Norwegian hospital trust as judged by retrospective chart review
Rogne T, Nordseth T, Marhaug G, Berg EM, Tromsdal A, Sæther O, Gisvold S, Hatlen P, Hogan H, Solligård E. Rate of avoidable deaths in a Norwegian hospital trust as judged by retrospective chart review. BMJ Quality & Safety 2018, 28: 49. PMID: 30026281, DOI: 10.1136/bmjqs-2018-008053.Peer-Reviewed Original ResearchConceptsHospital deathAvoidable deathsNorwegian hospital trustMandatory reporting systemRetrospective case record reviewHospital trustsRetrospective chart reviewHigh-risk populationCase record reviewReporting systemUnselected sampleChart reviewRecord reviewDeath groupSurgical departmentUnselected populationSuch deathsPatientsHealth policyDeathLife expectancyRegular reviewReport systemGreater proportionReview