Iron status and the risk of sepsis and severe COVID-19: a two-sample Mendelian randomization study
Mohus RM, Flatby H, Liyanarachi KV, DeWan AT, Solligård E, Damås JK, Åsvold BO, Gustad LT, Rogne T. Iron status and the risk of sepsis and severe COVID-19: a two-sample Mendelian randomization study. Scientific Reports 2022, 12: 16157. PMID: 36171422, PMCID: PMC9516524, DOI: 10.1038/s41598-022-20679-6.Peer-Reviewed Original ResearchConceptsRisk of sepsisTwo-sample Mendelian randomization studyIron statusMendelian randomization studySerum ironOdds ratioCOVID-19Randomization studyTotal iron binding capacitySevere COVID-19Risk of hospitalizationHigh iron statusIron binding capacitySex-stratified analysesTransferrin saturationSevere infectionsIron biomarkersObservational studyHigh riskSepsisStandard deviation increaseHospitalizationFurther studiesRiskStatus