Rolando Garcia Milian, MLS, AHIP
Biomedical Sciences Research Support Librarian and Lecturer in EpidemiologyDownloadHi-Res Photo
Cards
Additional Titles
Bioinformatics Support, Fellow of Ezra Stiles College, Medical Library
Publications Overview
- 76 Publications
- 1,274 Citations
- 93 Yale Co-Authors
Contact Info
Cushing/Whitney Medical Library
PO Box 208014, 333 Cedar St
New Haven, CT 06520
United States
Additional Titles
Bioinformatics Support, Fellow of Ezra Stiles College, Medical Library
Publications Overview
- 76 Publications
- 1,274 Citations
- 93 Yale Co-Authors
Contact Info
Cushing/Whitney Medical Library
PO Box 208014, 333 Cedar St
New Haven, CT 06520
United States
Additional Titles
Bioinformatics Support, Fellow of Ezra Stiles College, Medical Library
Publications Overview
- 76 Publications
- 1,274 Citations
- 93 Yale Co-Authors
Contact Info
Cushing/Whitney Medical Library
PO Box 208014, 333 Cedar St
New Haven, CT 06520
United States
About
Copy Link
Titles
Biomedical Sciences Research Support Librarian and Lecturer in Epidemiology
Bioinformatics Support, Fellow of Ezra Stiles College, Medical Library
Biography
Rolando oversees the Yale Medical Library Bioinformatics Support Program and is Lecturer in Epidemiology for the Environmental Health Sciences (EHS) Department, Yale School of Public Health. This end-user-centered bioinformatics program provides resources, training, consultations, and collaboration to biomedical sciences researchers at Yale including finding, retrieving, analyzing and sharing molecular datasets.
Last Updated on March 25, 2025.
Appointments
Environmental Health Sciences
LecturerSecondary
Other Departments & Organizations
- All Institutions
- Cushing/Whitney Medical Library
- Environmental Health Sciences
- NIDA Neuroproteomics Center
- Yale School of Public Health
- Yale-BI Biomedical Data Science Fellowship
Education & Training
- Biomedical Informatics Fellow
- Marine Biological Laboratory/ National Library of Medicine (2012)
- MLS
- Southern Connecticut State University (2012)
Research
Copy Link
Overview
Medical Research Interests
Chemicals and Drugs; Diseases; Genomics; Information Science; Metabolomics; Proteomics
Public Health Interests
Genetics, Genomics, Epigenetics; Toxicology
ORCID
0000-0003-1557-566XBioinformatics Support Hub
The Bioinformatics Support Hub provides resources, training, consultation, and collaboration for omics data analysis.
View Lab Website
Research at a Glance
Yale Co-Authors
Frequent collaborators of Rolando Garcia Milian's published research.
Publications Timeline
A big-picture view of Rolando Garcia Milian's research output by year.
Research Interests
Research topics Rolando Garcia Milian is interested in exploring.
David Thompson
TuKiet Lam, PhD, BS
Ying Chen, MD, PhD
Caroline Helen Johnson, PhD
Xingguang Luo, MD
Chiang-Shan Ray Li, MD, PhD
76Publications
1,274Citations
Proteomics
Metabolomics
Publications
Featured Publications
Peer Teaching as Bioinformatics Training Strategy: Incentives, Challenges, and Benefits
Rahman NT, Meyer C, Thakral D, Cai WL, Chen AT, Obaid R, Garcia-Milian R. Peer Teaching as Bioinformatics Training Strategy: Incentives, Challenges, and Benefits. Medical Reference Services Quarterly 2022, 41: 13-25. PMID: 35225737, DOI: 10.1080/02763869.2022.2020568.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsPeer teachingProfessional development opportunitiesResearch-intensive institutionsPeer teachersClassroom managementLack of timeTeachingCommunication skillsDevelopment opportunitiesTeachersComplex conceptBioinformatics trainingPersonal experienceTraining strategySkillsChallengesPeersTraineesInstitutionsWorkshopTrainingExperienceConfidenceOpportunitiesTopic
2026
Cross-Platform Proteomics and Machine Learning Algorithms Nominate Plasma Biomarkers of Stroke Diagnosis.
Misra S, Jang W, Sanchez S, Natu A, Kumar P, Liu M, Kaur A, Lopez V, Caglayan P, Garcia-Milian R, Watson C, Frankel M, Falcone G, Sansing L, Rangaraju S. Cross-Platform Proteomics and Machine Learning Algorithms Nominate Plasma Biomarkers of Stroke Diagnosis. Journal Of The American Heart Association 2026, 15: e048249. PMID: 41804885, DOI: 10.1161/jaha.125.048249.Peer-Reviewed Original ResearchAltmetricMeSH Keywords and ConceptsConceptsMass spectrometryTransient ischemic attackData-independent acquisition mass spectrometryAcute ischemic strokeIschemic attackStroke mimicsIntracerebral hemorrhageIschemic strokeExternal validation cohortSelection operator logistic regressionStroke subtypesCase-control studyProtein biomarkersStroke diagnosisTargeted Mass SpectrometryBlood-based biomarkersEnriched proteinsMulticenter cohortValidation cohortIndependent cohortSpectrometryPlasma biomarkersClinical covariatesEmergency settingProtein panelParkin deficiency impairs female fertility, oocyte development, fertilization and mitochondrial function in mice
Volovsky M, Rodríguez-Eguren A, Ergun Y, Yildirim R, Sahin G, Garcia Milian R, Mehta S, Turanli L, Cervelló I, Scott R, Seli E. Parkin deficiency impairs female fertility, oocyte development, fertilization and mitochondrial function in mice. Npj Aging 2026, 12: 33. PMID: 41571641, PMCID: PMC12916830, DOI: 10.1038/s41514-026-00332-6.Peer-Reviewed Original ResearchConceptsWild typeOocyte yieldMitochondrial E3 ubiquitin ligaseKO miceParkin deficiencyE3 ubiquitin ligaseMII oocyte countFemale fertilityUbiquitin ligaseCellular homeostasisExpressed genesFertilizing capacityRNA sequencingMitochondrial functionYoung miceOld miceParkinParkin deletionReproductive competenceOocyte countParkin knockoutMiceFemale reproductionPathway changesOverall fertility
2025
LET-7b-5b DRIVES A PRO-MIGRATORY AND ANTI-ANGIOGENIC PHENOTYPE IN FIRST TRIMESTER TROPHOBLAST CELLS THROUGH TLR7 AND TLR8 ACTIVATION
Siegel E, Esencan E, Kishchanka A, Garcia-Milian R, Tyagi A, Abrahams V, Pal L. LET-7b-5b DRIVES A PRO-MIGRATORY AND ANTI-ANGIOGENIC PHENOTYPE IN FIRST TRIMESTER TROPHOBLAST CELLS THROUGH TLR7 AND TLR8 ACTIVATION. Fertility And Sterility 2025, 124: e53-e54. DOI: 10.1016/j.fertnstert.2025.07.209.Peer-Reviewed Original ResearchIn Vivo PET Imaging of Preynaptic Density Reveals Stress-Associated Synaptic Deficits Related to Behavioral and Molecular Alterations in Rats
Asch R, Martin N, Garcia-Milian R, Fowles K, DiLeone R, Cai Z, Liston C, Esterlis I. In Vivo PET Imaging of Preynaptic Density Reveals Stress-Associated Synaptic Deficits Related to Behavioral and Molecular Alterations in Rats. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2025 PMID: 41038318, PMCID: PMC12614775, DOI: 10.1016/j.bpsc.2025.09.021.Peer-Reviewed Original ResearchConceptsNovel object recognitionPrefrontal cortexPositron emission tomographySucrose preferenceSynaptic densityChronic stressExposed to chronic unpredictable stressIn vivo PET imagingRodent models of chronic stressModel of chronic stressFemale Long-Evans ratsChronic unpredictable stressIn vivo positron emission tomographyStress-related pathologiesLong-Evans ratsRodent modelsRats relative to controlsIn vivo quantificationRelative to controlsUnpredictable stressBehavioral phenotypesSynaptic deficitsHippocampal proteinsSynaptic density changesSynaptic vesicle protein 2ADistinct metabolic and genetic alterations in tumors from early-onset versus late-onset colorectal cancer
Janak A, Jain A, Garcia-Milian R, Aladelokun O, Ma X, Paty P, Khan S, Johnson C. Distinct metabolic and genetic alterations in tumors from early-onset versus late-onset colorectal cancer. Free Radical Biology And Medicine 2025, 240: 773-782. PMID: 40865779, PMCID: PMC12990094, DOI: 10.1016/j.freeradbiomed.2025.08.052.Peer-Reviewed Original ResearchCitationsAltmetricConceptsLate-onset colorectal cancerEO-CRCColorectal cancerTumor metabolomeMass spectrometry-based untargeted metabolomicsTumor tissuesCatecholamine metabolismGroup of CRC patientsMetabolite set enrichment analysisPatient-matched normal tissuesTumor-specific differencesEarly-onset colorectal cancerMetabolite of dopaminePD-L1Untargeted metabolomicsCRC patientsOxidative stress-related genesHomovanillic acidGenetic alterationsEarly-onsetTumorTherapeutic strategiesGene expression validationNormal tissuesEGFR SignalingThe Proteomic Landscape of Parkin-Deficient and Parkin-Overexpressing Rat Nucleus Accumbens: An Insight into the Role of Parkin in Methamphetamine Use Disorder
Sharma A, Atasi T, Collin F, Wang W, Lam T, Garcia-Milian R, Arroum T, Pham L, Hüttemann M, Moszczynska A. The Proteomic Landscape of Parkin-Deficient and Parkin-Overexpressing Rat Nucleus Accumbens: An Insight into the Role of Parkin in Methamphetamine Use Disorder. Biomolecules 2025, 15: 958. PMID: 40723830, PMCID: PMC12292523, DOI: 10.3390/biom15070958.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsMETH use disorderMethamphetamine use disorderNucleus accumbensAddictive behaviorsUse disorderAdult Long-Evans male ratsLong-Evans male ratsProteomic landscapeRat nucleus accumbensMale ratsFDA-approved pharmacotherapiesActin cytoskeleton dynamicsYoung adult male ratsDrug targetsAdult male ratsAMPA receptor traffickingRat modelLabel-free proteomicsGABAergic neurotransmissionCytoskeleton dynamicsMethamphetamineUbiquitinated proteinsMitochondrial respirationAccumbensParkin deficiencyProliferative arrest induces neuronal differentiation and innate immune responses in normal and Creutzfeldt-Jakob Disease agent (CJ) infected rat septal neurons
Pagano N, Perez G, Garcia-Milian R, Manuelidis L. Proliferative arrest induces neuronal differentiation and innate immune responses in normal and Creutzfeldt-Jakob Disease agent (CJ) infected rat septal neurons. PLOS ONE 2025, 20: e0323825. PMID: 40434970, PMCID: PMC12118874, DOI: 10.1371/journal.pone.0323825.Peer-Reviewed Original ResearchAltmetricMeSH Keywords and ConceptsConceptsSeptal neuronsInnate immune responseDifferential transcriptionCreutzfeldt-Jakob disease agentCJ infectionImmune responseBind misfolded proteinsInnate immune genesIntestinal myeloid cellsRat septal neuronsArrests normal cellsDisease agentsInnate immune transcriptsCreutzfeldt-JakobModel of latent infectionAnti-viral responseCDNA libraryUnique transcriptsPeripheral human bloodLate-onset diseaseUninfected neuronsUpregulated interferonImmune genesMyeloid cellsTranscription270. Sex-Differences in Molecular and Synaptic Mechanisms Contributing to Stress-Related pathology: Insight from a Synaptic Density Pet and Proteomic Study in Rats
Asch R, Garcia-Milian R, Hernandez-Martin N, Cai Z, Esterlis I. 270. Sex-Differences in Molecular and Synaptic Mechanisms Contributing to Stress-Related pathology: Insight from a Synaptic Density Pet and Proteomic Study in Rats. Biological Psychiatry 2025, 97: s207. DOI: 10.1016/j.biopsych.2025.02.508.Peer-Reviewed Original ResearchTranscriptomic landscape of cumulus cells from patients <38 years old with a history of poor ovarian response (POR) treated with platelet-rich plasma (PRP)
Roberts L, Herlihy N, Reig A, Titus S, Garcia-Milian R, Knight J, Yildirim R, Margolis C, Cakiroglu Y, Tiras B, Whitehead C, Werner M, Seli E. Transcriptomic landscape of cumulus cells from patients <38 years old with a history of poor ovarian response (POR) treated with platelet-rich plasma (PRP). Aging 2025, 17: 431-447. PMID: 39976580, PMCID: PMC11892918, DOI: 10.18632/aging.206202.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsPlatelet-rich plasmaTreated with platelet-rich plasmaCumulus cellsPoor ovarian responseLive birthsGene expressionIntraovarian injection of autologous platelet-rich plasmaPatients treated with platelet-rich plasmaInjection of autologous platelet-rich plasmaHistory of poor ovarian responseAutologous platelet-rich plasmaPlatelet-rich plasma treatmentDiminished ovarian reserveCell-to-cell signalingRNA sequencing librariesCause of infertilityDifferential expression analysisFalse discovery rate thresholdIntraovarian injectionOvarian reserveFailed implantsSequencing librariesOvarian responseTranscriptomic landscapeRNA sequencing
Academic Achievements & Community Involvement
Copy Link
Activities
activity Academy of Health Information Professionals
04/15/2018 - PresentProfessional OrganizationsCommittee Memberactivity International Society for Computational Biology
2020 - PresentProfessional OrganizationsMemberactivity Institutional Animal Care & Use Committee
06/01/2014 - 05/01/2018CommitteesCommittee Member
News & Links
Copy Link
Media
- Network representation of the research articles resulting from collaborations between Medical Library Bioinformatics Support Program and groups/departments at the YSM
News
Related Links
Get In Touch
Copy Link
Contacts
Academic Office Number
Office Fax Number
Mailing Address
Cushing/Whitney Medical Library
PO Box 208014, 333 Cedar St
New Haven, CT 06520
United States
Locations
Bioinformatics Support Hub
Lab
Sterling Hall of Medicine
333 Cedar Street, Rm SHM L-103
New Haven, CT 06510