Challenging the concept of de novo acute myeloid leukemia: Environmental and occupational leukemogens hiding in our midst
Shallis RM, Weiss JJ, Deziel NC, Gore SD. Challenging the concept of de novo acute myeloid leukemia: Environmental and occupational leukemogens hiding in our midst. Blood Reviews 2020, 47: 100760. PMID: 32988660, DOI: 10.1016/j.blre.2020.100760.Peer-Reviewed Original ResearchMeSH KeywordsBone MarrowCarcinogenesisCarcinogensEnvironmental ExposureHumansLeukemia, Myeloid, AcuteOccupational ExposureRisk FactorsTumor MicroenvironmentConceptsAcute myeloid leukemiaDe novo acute myeloid leukemiaNovo acute myeloid leukemiaMyeloid leukemiaRisk of AMLTherapy-related acute myeloid leukemiaParticular chemotherapeutic agentsOccupational exposureIndividual patientsMyeloid neoplasmsGermline predispositionAccidental exposureLeukemogenChemotherapeutic agentsMarrow microenvironmentLeukemiaEnvironmental agentsAcceptable exposure limitsCell acquisitionPatientsExposure limitsExposureInescapable exposureAmbient exposureRisk