2024
Nitrate exposure from drinking water and dietary sources among Iowa farmers using private wells
Skalaban T, Thompson D, Madrigal J, Blount B, Espinosa M, Kolpin D, Deziel N, Jones R, Beane Freeman L, Hofmann J, Ward M. Nitrate exposure from drinking water and dietary sources among Iowa farmers using private wells. The Science Of The Total Environment 2024, 919: 170922. PMID: 38350573, DOI: 10.1016/j.scitotenv.2024.170922.Peer-Reviewed Original ResearchConceptsMaximum contaminant levelUrinary nitrate concentrationDietary intakeNitrate concentrationsNitrate excretionNitrate exposureDietary nitrateDrinking waterDietary assessment toolsPrivate wellsAssociated with adverse health risksVulnerable to nitrate contaminationWater nitrate concentrationsNitrate ingestionAdverse health risksAgricultural Health StudyDrinking water intakeMedian intakeProspective cohortUrinary nitrateDietary nitrate ingestionContamination levelsNitrate contaminationNitrate intakeHealth Study
2023
Urinary Paraben Concentrations and Associations with the Periconceptional Urinary Metabolome: Untargeted and Targeted Metabolomics Analyses of Participants from the Early Pregnancy Study
Vollmar A, Rattray N, Cai Y, Jain A, Yan H, Deziel N, Calafat A, Wilcox A, Jukic A, Johnson C. Urinary Paraben Concentrations and Associations with the Periconceptional Urinary Metabolome: Untargeted and Targeted Metabolomics Analyses of Participants from the Early Pregnancy Study. Environmental Health Perspectives 2023, 131: 097006. PMID: 37702489, PMCID: PMC10498870, DOI: 10.1289/ehp12125.Peer-Reviewed Original ResearchConceptsUrinary paraben concentrationsDiet-related metabolitesEarly Pregnancy StudyUrinary metabolomePregnancy StudyParaben concentrationsReproductive functionMultivariable linear regressionFemale reproductive functionDietary exposure assessmentUltrahigh-performance liquid chromatography-quadrupole timeMetabolomic analysisParaben exposureProspective cohortLiquid chromatography-quadrupole timeOrthogonal partial least squares discriminant analysisPericonceptional periodPotential confoundersUrinary concentrationsMetabolomic markersNutritional epidemiologyUnivariate statistical analysisExposure informationCritical windowUrine samples
2022
Urinary phenol concentrations and fecundability and early pregnancy loss
Vollmar A, Weinberg C, Baird D, Wilcox A, Calafat A, Deziel N, Johnson C, Jukic A. Urinary phenol concentrations and fecundability and early pregnancy loss. Human Reproduction 2022, 38: 139-155. PMID: 36346334, PMCID: PMC10089295, DOI: 10.1093/humrep/deac230.Peer-Reviewed Original ResearchConceptsEarly pregnancy lossPregnancy lossUrinary phenol concentrationsIntraclass correlation coefficientMenstrual cycleNational InstituteDaily first-morning urine specimensPhenol exposureEnvironmental Health SciencesFirst morning urine specimensLogistic regressionSTUDY FUNDING/COMPETINGMultivariable logistic regressionPARTICIPANTS/MATERIALSROLE OF CHANCEIntramural Research ProgramClinical miscarriageProspective cohortIncreased oddsLive birthsEpidemiologic studiesUrine specimensHealth SciencesEndocrine-disrupting potentialReproductive function