Accounting for urinary dilution in peri-implantation samples: implications for creatinine adjustment and specimen pooling
Rosen Vollmar AK, Johnson CH, Weinberg CR, Deziel NC, Baird DD, Wilcox AJ, Jukic AMZ. Accounting for urinary dilution in peri-implantation samples: implications for creatinine adjustment and specimen pooling. Journal Of Exposure Science & Environmental Epidemiology 2020, 31: 356-365. PMID: 32424331, PMCID: PMC7671945, DOI: 10.1038/s41370-020-0227-1.Peer-Reviewed Original ResearchConceptsCreatinine adjustmentCreatinine concentrationUrinary dilutionUrinary estrogen metabolitesEffect of pregnancyUrinary creatinine concentrationCreatinine levelsWeeks' gestationEarly pregnancyCreatinine excretionEstrogen metabolitesCreatinine measuresUrine specimensPooled measureBiomarker measurementsPooled specimensEnvironmental exposuresExposure measuresLinear mixed modelsBiomonitoring resultsPregnancyT-testKappa coefficientMixed modelsPerson sampleAssessing Endogenous and Exogenous Hormone Exposures and Breast Development in a Migrant Study of Bangladeshi and British Girls
Howland RE, Deziel NC, Bentley GR, Booth M, Choudhury OA, Hofmann JN, Hoover RN, Katki HA, Trabert B, Fox SD, Troisi R, Houghton LC. Assessing Endogenous and Exogenous Hormone Exposures and Breast Development in a Migrant Study of Bangladeshi and British Girls. International Journal Of Environmental Research And Public Health 2020, 17: 1185. PMID: 32069802, PMCID: PMC7068451, DOI: 10.3390/ijerph17041185.Peer-Reviewed Original ResearchConceptsEstrogen metabolitesBPA-glucuronideBreast developmentMigrant studiesBreast cancer incidenceEndogenous estrogen levelsBisphenol A (BPA) exposureExogenous hormone exposureCross-sectional studyBangladeshi girlsTime of interviewUrine spot samplesHazard ratioEstrogen levelsA ExposureCancer incidenceEarlier thelarcheTanner stageUbiquitous exposureHormone exposureThelarcheLiquid chromatography-tandem mass spectrometryConfidence intervalsWhite BritishAdolescent girls