2020
Exposure to polychlorinated biphenyls and organochlorine pesticides and thyroid cancer in connecticut women
Deziel NC, Warren JL, Huang H, Zhou H, Sjodin A, Zhang Y. Exposure to polychlorinated biphenyls and organochlorine pesticides and thyroid cancer in connecticut women. Environmental Research 2020, 192: 110333. PMID: 33068584, PMCID: PMC7736223, DOI: 10.1016/j.envres.2020.110333.Peer-Reviewed Original ResearchConceptsPapillary thyroid cancerThyroid cancerPCBs/OCPsOdds ratioSubsequent thyroid cancer riskMulti-pollutant modelingSerum Polychlorinated BiphenylsBody mass indexConfidence intervalsThyroid cancer riskThyroid cancer incidenceEarly life exposureEnvironmental risk factorsSingle-pollutant modelsLogistic regression modelsIsotope dilution high-resolution mass spectrometryMass indexTumor sizeCancer incidenceRisk factorsConnecticut womenFamily historyMulti-pollutant analysisCancer riskThyroid hormone disruptorsDioxin exposure and breast cancer risk in a prospective cohort study
VoPham T, Bertrand KA, Jones RR, Deziel NC, DuPré NC, James P, Liu Y, Vieira VM, Tamimi RM, Hart JE, Ward MH, Laden F. Dioxin exposure and breast cancer risk in a prospective cohort study. Environmental Research 2020, 186: 109516. PMID: 32305677, PMCID: PMC7363533, DOI: 10.1016/j.envres.2020.109516.Peer-Reviewed Original ResearchConceptsNurses' Health Study IIBreast cancer riskInvasive breast cancer riskHealth Study IICancer riskDioxin exposureHazard ratioBreast cancer risk factorsInvasive breast cancer casesInvasive breast cancer diagnosisER- breast cancerMedical record reviewProspective cohort studyCancer risk factorsConfidence intervalsBreast cancer casesResidential proximityGeocoded residential addressesPositive associationBreast cancer diagnosisBiennial questionnairesCohort studyMenopausal statusRecord reviewRisk factors
2018
A case-control study of exposure to organophosphate flame retardants and risk of thyroid cancer in women
Deziel NC, Yi H, Stapleton HM, Huang H, Zhao N, Zhang Y. A case-control study of exposure to organophosphate flame retardants and risk of thyroid cancer in women. BMC Cancer 2018, 18: 637. PMID: 29871608, PMCID: PMC5989427, DOI: 10.1186/s12885-018-4553-9.Peer-Reviewed Original ResearchConceptsCase-control studyThyroid cancer riskPFR exposureThyroid cancerPFR metabolitesOdds ratioCancer riskPapillary thyroid cancer casesUrinary biomarker measurementsTime of diagnosisLarger tumor sizeCancer case-control studySpot urine samplesThyroid cancer casesPapillary thyroid cancer riskTumor sizePotential confoundersThyroid hormone regulationUrinary concentrationsCancer casesMultiple linear regression analysisFemale controlsLinear regression analysisBackgroundGrowing evidenceBiomarker measurements