2021
A murine model of the human CREBRFR457Q obesity-risk variant does not influence energy or glucose homeostasis in response to nutritional stress
Kanshana JS, Mattila PE, Ewing MC, Wood AN, Schoiswohl G, Meyer AC, Kowalski A, Rosenthal SL, Gingras S, Kaufman BA, Lu R, Weeks DE, McGarvey ST, Minster RL, Hawley NL, Kershaw EE. A murine model of the human CREBRFR457Q obesity-risk variant does not influence energy or glucose homeostasis in response to nutritional stress. PLOS ONE 2021, 16: e0251895. PMID: 34520472, PMCID: PMC8439463, DOI: 10.1371/journal.pone.0251895.Peer-Reviewed Original ResearchConceptsMurine modelGlucose homeostasisEnergy/glucose homeostasisOdds of diabetesOdds of obesityObesity risk variantsAlternative preclinical modelsPromotes obesityPreclinical modelsKnockin miceObesityDiabetesStrong heritable componentExtensive phenotypic analysisMissense variantsOrthologous variantDiseaseMiceOddsAdaptive transcriptional responseExtreme nutritional stressNutritional stressHomeostasisGenetic contributionRegulatory factorsSocial Support for Self-Care: Patient Strategies for Managing Diabetes and Hypertension in Rural Uganda
Tusubira AK, Nalwadda CK, Akiteng AR, Hsieh E, Ngaruiya C, Rabin TL, Katahoire A, Hawley NL, Kalyesubula R, Ssinabulya I, Schwartz JI, Armstrong-Hough M. Social Support for Self-Care: Patient Strategies for Managing Diabetes and Hypertension in Rural Uganda. Annals Of Global Health 2021, 87: 86. PMID: 34458110, PMCID: PMC8378074, DOI: 10.5334/aogh.3308.Peer-Reviewed Original ResearchConceptsNon-communicable diseasesSelf-care practicesPrescribed medicinesConventional medicinePatient's social support networkRural UgandaSelf-care activitiesBlood sugar levelsCross-sectional qualitative studyResource-limited settingsSelf-care effortsSocial support networksSocial supportNCD clinicsNineteen patientsAdult patientsHealth facilitiesPatientsPatient strategiesManaging diabetesHypertensionSelf-CareDiabetesDiagnostic testsLow-income countries
2020
Longitudinal Assessment of Childhood Dietary Patterns: Associations with Body Mass Index z-Score among Children in the Samoan Ola Tuputupua'e (Growing Up) Cohort
Choy CC, Wang D, Naseri T, Soti-Ulberg C, Reupena MS, Duckham RL, Baylin A, Hawley NL. Longitudinal Assessment of Childhood Dietary Patterns: Associations with Body Mass Index z-Score among Children in the Samoan Ola Tuputupua'e (Growing Up) Cohort. Childhood Obesity 2020, 16: 534-543. PMID: 32907355, PMCID: PMC7575349, DOI: 10.1089/chi.2020.0058.Peer-Reviewed Original ResearchConceptsDietary patternsHigh adherenceBody mass index zChildhood obesity prevention strategiesObesity prevention strategiesBody mass indexFood frequency dataChildhood dietary patternsBiological mother-child dyadsCohort studyMass indexPattern adherencePotential confoundersChildhood obesityPrevention strategiesMother-child dyadsLongitudinal assessmentTime pointsConvenience sampleAdherenceBMIzIntervention strategiesChildrenScoresAssociationPiloting a food photo sorting activity in Samoa to assess maternal beliefs and their role in child diet
Tanawattanacharoen VK, Choy CC, Anesi TJ, Naseri T, Soti‐Ulberg C, Reupena MS, Hawley NL. Piloting a food photo sorting activity in Samoa to assess maternal beliefs and their role in child diet. Maternal And Child Nutrition 2020, 16: e12974. PMID: 32056393, PMCID: PMC7296816, DOI: 10.1111/mcn.12974.Peer-Reviewed Original ResearchConceptsChildren's dietary intakeDietary intakeChildhood obesityChildren's dietsHealthier child dietMaternal beliefsAlarming burdenSamoan mothersKnowledge/beliefsNutritional knowledgeEating habitsNutritional expertsIntakeHealthy foodsMothersObesityCountry settingsCost of foodStatusDietPearson correlationFood costsAdditional supportParental beliefsFood