2024
Associations between fasting glucose rate-of-change and the missense variant, rs373863828, in an adult Samoan cohort
Rivara A, Russell E, Carlson J, Pomer A, Naseri T, Reupena M, Manna S, Viali S, Minster R, Weeks D, DeLany J, Kershaw E, McGarvey S, Hawley N. Associations between fasting glucose rate-of-change and the missense variant, rs373863828, in an adult Samoan cohort. PLOS ONE 2024, 19: e0302643. PMID: 38829901, PMCID: PMC11146712, DOI: 10.1371/journal.pone.0302643.Peer-Reviewed Original ResearchConceptsType 2 diabetesAllele of rs373863828Body mass indexFasting glucoseAdult SamoansDevelopment of type 2 diabetesOdds of type 2 diabetesReduction of modifiable risk factorsRs373863828 genotypeAssociated with higher body mass indexType 2 diabetes developmentGlucose rate of changeMass indexHousehold asset scoreUrbanization of residenceHigher body mass indexRisk factorsModifiable risk factorsRate of changeBaseline variablesMultivariate linear regressionPhysical activityDiabetes preventionType 2 diabetes mellitusSmoking status
2023
Association between age at menarche and cardiometabolic risk among Samoan adults
Oyama S, Duckham R, Pomer A, Rivara A, Kershaw E, Wood A, Fidow U, Naseri T, Reupena M, Viali S, McGarvey S, Hawley N. Association between age at menarche and cardiometabolic risk among Samoan adults. American Journal Of Human Biology 2023, 36: e23982. PMID: 37668413, PMCID: PMC10845161, DOI: 10.1002/ajhb.23982.Peer-Reviewed Original ResearchConceptsCardiometabolic riskOne-year increaseSubsequent cardiometabolic riskOdds of hypertensionHigher total cholesterolOdds of diabetesOdds of obesityEarly life exposureFat-free massCardiometabolic morbiditySerum lipidsBlood pressureMedian ageMetabolic syndromeTotal cholesterolProspective studyChildhood adiposityInsulin resistanceObesity prevalenceLife exposureSamoan adultsLean massEarly menarcheLogistic regressionMenarche
2022
The missense variant, rs373863828, in CREBRF plays a role in longitudinal changes in body mass index in Samoans
Fu H, Hawley NL, Carlson JC, Russell EM, Pomer A, Cheng H, Naseri T, Reupena M, Deka R, Choy CC, McGarvey ST, Minster RL, Weeks DE. The missense variant, rs373863828, in CREBRF plays a role in longitudinal changes in body mass index in Samoans. Obesity Research & Clinical Practice 2022, 16: 220-227. PMID: 35606300, PMCID: PMC9373717, DOI: 10.1016/j.orcp.2022.04.004.Peer-Reviewed Original ResearchConceptsBMI rateHousehold asset scoreAA genotypeBody mass indexMissense variantsBMI of femalesSex-stratified modelsHigh rateAG participantsBaseline BMIMean BMICohort studyMass indexSamoan adultsPhysical activityGG genotypeBMIAge groupsA alleleLongitudinal changesAsset scoreRs373863828Older participantsFemalesCREBRF