2002
Steroids for acute spinal cord injury
Bracken M. Steroids for acute spinal cord injury. 2002, cd001046. PMID: 12137616, DOI: 10.1002/14651858.cd001046.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsAcute spinal cord injurySpinal cord injuryHours of injuryCord injuryMethylprednisolone therapySteroid treatmentPharmacological therapyRandomized trialsRecent trialsNational Acute Spinal Cord Injury StudyAcute Spinal Cord Injury StudyHigh-dose methylprednisolone steroid therapySpinal Cord Injury StudyMotor neurologic functionOnly pharmacological therapyNorth American trialsLumbar disc diseaseStart of treatmentMethylprednisolone sodium succinateCochrane Injuries GroupYears post injurySteroid therapyMaintenance infusionDose regimenInjury group
2001
Methylprednisolone and Acute Spinal Cord Injury
Bracken M. Methylprednisolone and Acute Spinal Cord Injury. Spine 2001, 26: s47-s54. PMID: 11805609, DOI: 10.1097/00007632-200112151-00010.Peer-Reviewed Original ResearchConceptsAcute spinal cord injurySpinal cord injuryCord injuryMethodologic qualitySystematic reviewImproved functional recoveryHigh methodologic qualityNeurologic recoveryClinical recoveryPharmacologic therapyFunctional recoveryRandomized trialsInjury trialsCochrane LibraryEffective therapySurgical trialsEarly treatmentFurther trialsTherapeutic interventionsInjuryMeSH headingsMethylprednisoloneScore improvementPatientsEvidence base
1994
Clinically useful measures of effect in binary analyses of randomized trials
Sinclair J, Bracken M. Clinically useful measures of effect in binary analyses of randomized trials. Journal Of Clinical Epidemiology 1994, 47: 881-889. PMID: 7730891, DOI: 10.1016/0895-4356(94)90191-0.Peer-Reviewed Original ResearchConceptsOdds ratioTreatment effectsHigher baseline riskRelative risk reductionRandomized clinical trialsControl group risksGroups of trialsLarge treatment effectsPhysician appreciationRandomized trialsRisk ratioClinical trialsRelative riskBaseline riskTreatment decisionsClinical questionsRisk differenceTrialsSingle trialRisk reductionRiskGroup riskPhysiciansAbsolute effectUseful measure