1993
Effects of timing of methylprednisolone or naloxone administration on recovery of segmental and long-tract neurological function in NASCIS 2.
Bracken M, Holford T. Effects of timing of methylprednisolone or naloxone administration on recovery of segmental and long-tract neurological function in NASCIS 2. Journal Of Neurosurgery 1993, 79: 500-7. PMID: 8410217, DOI: 10.3171/jns.1993.79.4.0500.Peer-Reviewed Original ResearchConceptsNational Acute Spinal Cord Injury StudyNeurological recoveryIncomplete injuriesNeurological functionNaloxone administrationClinical managementAcute Spinal Cord Injury StudySpinal Cord Injury StudyHigh-dose methylprednisoloneLong spinal tractsHours of injuryUltimate therapeutic goalInjury levelConsiderable clinical significanceNarrow treatment windowMethylprednisolone treatmentSpinal tractClinical significanceSegmental functionInjury studiesTherapeutic goalsTreatment windowMethylprednisoloneHigh dosesInjuryPharmacological treatment of acute spinal cord injury: current status and future projects.
Bracken M. Pharmacological treatment of acute spinal cord injury: current status and future projects. Journal Of Emergency Medicine 1993, 11 Suppl 1: 43-8. PMID: 8445202.Peer-Reviewed Original ResearchConceptsAcute spinal cord injurySpinal cord injuryCord injurySecond National Acute Spinal Cord Injury StudyNational Acute Spinal Cord Injury StudyAcute Spinal Cord Injury StudySpinal Cord Injury StudyEffectiveness of methylprednisoloneMethylprednisolone-treated patientsRecovery of motorHours of injuryLevel of injuryMethylprednisolone groupPinprick sensationTirilazad mesylateMethylprednisolone infusionGlucocorticoid activityInitial bolusNeurological functionPharmacological treatmentMotor functionSpinal cordInjury studiesSensory functionInjury
1992
Methylprednisolone or naloxone treatment after acute spinal cord injury: 1-year follow-up data. Results of the second National Acute Spinal Cord Injury Study.
Bracken M, Shepard M, Collins W, Holford T, Baskin D, Eisenberg H, Flamm E, Leo-Summers L, Maroon J, Marshall L, Perot P, Piepmeier J, Sonntag V, Wagner F, Wilberger J, Winn H, Young W. Methylprednisolone or naloxone treatment after acute spinal cord injury: 1-year follow-up data. Results of the second National Acute Spinal Cord Injury Study. Journal Of Neurosurgery 1992, 76: 23-31. PMID: 1727165, DOI: 10.3171/jns.1992.76.1.0023.Peer-Reviewed Original ResearchConceptsHours of injuryAcute spinal cord injurySpinal cord injuryNaloxone treatmentCord injuryMotor functionSecond National Acute Spinal Cord Injury StudyNational Acute Spinal Cord Injury StudyAcute Spinal Cord Injury StudySpinal Cord Injury StudyAcute spinal cord traumaPreservation of motorTrial of methylprednisoloneSpinal cord traumaTotal sensoryPlacebo groupCord traumaNeurological functionStudy doseEmergency roomMethylprednisoloneInjury studiesMortality ratePatientsSensory function
1981
Psychological response to acute spinal cord injury: an epidemiological study
Bracken M, Shepard M, Webb S. Psychological response to acute spinal cord injury: an epidemiological study. Spinal Cord 1981, 19: 271-283. PMID: 7279429, DOI: 10.1038/sc.1981.53.Peer-Reviewed Original ResearchConceptsSpinal cord injuryCord injuryAcute spinal cord injurySeverity of motorTime of dischargeAcute care hospitalsAcute hospitalisationNeurological statusCare hospitalNeurological functionPsychological reactionsEpidemiological studiesRehabilitation therapyInjuryNegative coping responsesHospitalisationPsychological counsellingSensory disabilitiesPersonality reactionsPsychological responsesLesser degreeCoping reactionsPatientsAdmissionHospital
1980
Relationship between neurological and functional status after acute spinal cord injury: An epidemiological study
Bracken M, Hildreth N, Freeman D, Webb S. Relationship between neurological and functional status after acute spinal cord injury: An epidemiological study. Journal Of Clinical Epidemiology 1980, 33: 115-125. PMID: 7354100, DOI: 10.1016/0021-9681(80)90035-1.Peer-Reviewed Original ResearchConceptsSensory functionMotor functionFunctional statusFirst post-injury yearAcute spinal cord injurySpinal cord injurySelfcare activitiesFour-point scaleADL scoresHospital dischargeHospital admissionSensory lossNeurological functionProspective studyCord injuryDaily livingEpidemiological studiesMovement of limbsHospitalizationPatientsInjuryGreater improvementAdditive effectSignificant improvementStatus