2018
Tenascin-X in amniotic fluid and reproductive tissues of pregnancies complicated by infection and preterm prelabor rupture of membranes†
Rood KM, Buhimschi CS, Zhao G, Oliver EA, Summerfield T, Bahtiyar MO, Buhimschi IA. Tenascin-X in amniotic fluid and reproductive tissues of pregnancies complicated by infection and preterm prelabor rupture of membranes†. Biology Of Reproduction 2018, 100: 773-782. PMID: 30277495, PMCID: PMC6437262, DOI: 10.1093/biolre/ioy216.Peer-Reviewed Original ResearchConceptsIntra-amniotic infection/inflammationPreterm prelabor ruptureFetal membranesAmniotic fluidTNX expressionPrelabor ruptureInfection/inflammationLung maturity testingMembrane statusSpontaneous PPROMPregnancy complicationsNormal outcomeTherapeutic targetGenetic karyotypingReproductive tissuesPPROMMRNA expressionMaturity testingPregnancyWestern blottingMRNA levelsQRT-PCRExtracellular matrix proteinsCervixInflammation
2008
Relationships of maternal serum levels of vascular endothelial growth factor and tensile strength properties of the cervix in a rat model of chronic hypoxia
Sfakianaki AK, Buhimschi IA, Ravishankar V, Bahtiyar MO, Dulay AT, Buhimschi CS. Relationships of maternal serum levels of vascular endothelial growth factor and tensile strength properties of the cervix in a rat model of chronic hypoxia. American Journal Of Obstetrics And Gynecology 2008, 198: 223.e1-223.e7. PMID: 18226631, DOI: 10.1016/j.ajog.2007.09.054.Peer-Reviewed Original ResearchConceptsMaternal serum levelsVascular endothelial growth factorSerum levelsSignificant inverse correlationChronic hypoxiaEndothelial growth factorMaternal serum vascular endothelial growth factorSerum vascular endothelial growth factorAdult Sprague-Dawley ratsGrowth factorFree serum levelsInverse correlationRat uterine cervixSprague-Dawley ratsGroups of animalsHPx groupNonpregnant controlsUterine cervixHypoxic chamberRat modelMaternal bloodCervical stiffnessCervixCervical strengthDay 21