2011
Microbial Communities of the Upper Respiratory Tract and Otitis Media in Children
Laufer AS, Metlay JP, Gent JF, Fennie KP, Kong Y, Pettigrew MM. Microbial Communities of the Upper Respiratory Tract and Otitis Media in Children. MBio 2011, 2: 10.1128/mbio.00245-10. PMID: 21285435, PMCID: PMC3031303, DOI: 10.1128/mbio.00245-10.Peer-Reviewed Original ResearchConceptsOtitis mediaUpper respiratory tractS. pneumoniaeRespiratory tractOtitis media treatmentRespiratory virus seasonS. pneumoniae colonizationOtitis media pathogensCross-sectional studyOtitis media susceptibilityPneumoniae colonizationDecreased riskPneumococcal colonizationNasal swabsFrequent causePrevention strategiesStreptococcus pneumoniaeDemographic dataProtective floraPneumoniaeSwabsChildrenCausal pathwaysTractRisk
2007
Respiratory symptoms among infants at risk for asthma: association with surfactant protein A haplotypes
Pettigrew MM, Gent JF, Zhu Y, Triche EW, Belanger KD, Holford TR, Bracken MB, Leaderer BP. Respiratory symptoms among infants at risk for asthma: association with surfactant protein A haplotypes. BMC Medical Genomics 2007, 8: 15. PMID: 17407567, PMCID: PMC1852548, DOI: 10.1186/1471-2350-8-15.Peer-Reviewed Original ResearchConceptsPersistent coughSurfactant protein ARespiratory symptomsWhite infantsClinician-diagnosed asthmaInfant respiratory symptomsRespiratory symptom frequencyRisk of wheezeCohort of infantsSingle nucleotide polymorphismsMonths of ageQuarterly telephone interviewsLogistic regression modelsRace/ethnicityStudy infantsNewborn infantsSymptom frequencyInfant's birthStandardized questionnaireCoughWheezeAsthmaInfantsTelephone interviewsOlder children
2006
Variation in the Presence of Neuraminidase Genes among Streptococcus pneumoniae Isolates with Identical Sequence Types
Pettigrew MM, Fennie KP, York MP, Daniels J, Ghaffar F. Variation in the Presence of Neuraminidase Genes among Streptococcus pneumoniae Isolates with Identical Sequence Types. Infection And Immunity 2006, 74: 3360-3365. PMID: 16714565, PMCID: PMC1479257, DOI: 10.1128/iai.01442-05.Peer-Reviewed Original ResearchConceptsPneumoniae isolatesSequence typesUpper respiratory tractNeuraminidase geneS. pneumoniae isolatesVirulence determinantsStreptococcus pneumoniae isolatesIdentical sequence typesYoung childrenAdditional virulence determinantsSialic acid-containing substratesCapsule typesMultilocus sequence typesOtitis mediaInvasive diseaseRespiratory tractCarriage isolatesPneumococcal clonesSame sequence typePneumococcal strainsImportant causeStreptococcus pneumoniaeMiddle earDifferent tissue sourcesPneumococcal neuraminidase
2004
Association of early‐onset otitis media in infants and exposure to household mould
Pettigrew MM, Gent JF, Triche EW, Belanger KD, Bracken MB, Leaderer BP. Association of early‐onset otitis media in infants and exposure to household mould. Paediatric And Perinatal Epidemiology 2004, 18: 441-447. PMID: 15535820, DOI: 10.1111/j.1365-3016.2004.00596.x.Peer-Reviewed Original ResearchConceptsEarly otitis mediaOtitis mediaMonths of ageHousehold moldInfant respiratory symptomsAcute otitis mediaPhysician-diagnosed asthmaCohort of infantsOtitis media episodesRecurrent otitis mediaEarly onset otitis mediaMonths of lifeQuarterly telephone interviewsRespiratory symptomsCommon infectionsProspective studyPotential confoundersHigh riskInfant's birthStandardised questionnaireTelephone interviewsMonthsAsthmaEarly childhoodFurther studies
2003
Duration of Breastfeeding, Daycare, and Physician Visits among Infants 6 Months and Younger
Pettigrew MM, Khodaee M, Gillespie B, Schwartz K, Bobo JK, Foxman B. Duration of Breastfeeding, Daycare, and Physician Visits among Infants 6 Months and Younger. Annals Of Epidemiology 2003, 13: 431-435. PMID: 12875801, DOI: 10.1016/s1047-2797(02)00463-5.Peer-Reviewed Original ResearchConceptsDuration of breastfeedingAdditional childrenInfants 6 monthsHealth care providersFirstborn childrenPhysician visitsWeeks postpartumMonths postpartumBirthing centerCare providersBreastfeedingNumber of childrenAdditional weeksMailed questionnaireInfantsWomenChildrenPostpartumDurationVisitsMonthsDaycareSuburban DetroitIllnessWeeks