The human microbiota: novel targets for hospital-acquired infections and antibiotic resistance
Pettigrew MM, Johnson JK, Harris AD. The human microbiota: novel targets for hospital-acquired infections and antibiotic resistance. Annals Of Epidemiology 2016, 26: 342-347. PMID: 26994507, PMCID: PMC4892961, DOI: 10.1016/j.annepidem.2016.02.007.Peer-Reviewed Original ResearchConceptsMultidrug-resistant organismsSpread of MDROsInfection control interventionsHealth care settingsCare settingsColonization resistanceControl interventionsTraditional infection control measuresInfection control measuresAntibiotic resistanceControl of MDROsHospital-acquired infectionsHealth care professionalsHospitalized patientsIntact microbiotaAntibiotic useMDRO transmissionEpidemiologic studiesInfection controlAntimicrobial stewardshipCare professionalsHealthy microbiotaExpansion of pathogensResistant organismsNovel targetPseudomonas aeruginosa Colonization in the Intensive Care Unit: Prevalence, Risk Factors, and Clinical Outcomes
Harris AD, Jackson SS, Robinson G, Pineles L, Leekha S, Thom KA, Wang Y, Doll M, Pettigrew MM, Johnson JK. Pseudomonas aeruginosa Colonization in the Intensive Care Unit: Prevalence, Risk Factors, and Clinical Outcomes. Infection Control And Hospital Epidemiology 2016, 37: 544-548. PMID: 26832307, PMCID: PMC4833506, DOI: 10.1017/ice.2015.346.Peer-Reviewed Original ResearchConceptsIntensive care unitPseudomonas aeruginosa colonizationRisk factorsICU admissionClinical culturesCurrent hospitalizationAeruginosa colonizationCare unitIntensive care unit admissionP. aeruginosaSurgical intensive care unitPositive clinical cultureCare unit admissionEmpirical antibiotic therapyTertiary care hospitalType of ICUSignificant risk factorsP. aeruginosa colonizationRapid diagnostic testingPerirectal surveillance culturesUnit admissionCohort studyAntibiotic therapyCare hospitalClinical outcomes