2016
Association of sputum microbiota profiles with severity of community-acquired pneumonia in children
Pettigrew MM, Gent JF, Kong Y, Wade M, Gansebom S, Bramley AM, Jain S, Arnold SL, McCullers JA. Association of sputum microbiota profiles with severity of community-acquired pneumonia in children. BMC Infectious Diseases 2016, 16: 317. PMID: 27391033, PMCID: PMC4939047, DOI: 10.1186/s12879-016-1670-4.Peer-Reviewed Original ResearchConceptsCommunity-acquired pneumoniaCAP severityMicrobiota profilesClinical courseRespiratory microbiotaPediatric community-acquired pneumoniaIntensive care unit admissionNasopharyngeal/oropharyngeal samplesCare unit admissionOdds of lengthInduced sputum samplesRespiratory tract microbiotaOP samplesRibosomal RNA sequencingUnit admissionDecreased oddsSputum samplesChildren 6Oropharyngeal samplesMicrobiota influenceChildren 5Logistic regressionSputumSeverityPneumoniaPseudomonas aeruginosa Colonization in the Intensive Care Unit: Prevalence, Risk Factors, and Clinical Outcomes
Harris AD, Jackson SS, Robinson G, Pineles L, Leekha S, Thom KA, Wang Y, Doll M, Pettigrew MM, Johnson JK. Pseudomonas aeruginosa Colonization in the Intensive Care Unit: Prevalence, Risk Factors, and Clinical Outcomes. Infection Control And Hospital Epidemiology 2016, 37: 544-548. PMID: 26832307, PMCID: PMC4833506, DOI: 10.1017/ice.2015.346.Peer-Reviewed Original ResearchConceptsIntensive care unitPseudomonas aeruginosa colonizationRisk factorsICU admissionClinical culturesCurrent hospitalizationAeruginosa colonizationCare unitIntensive care unit admissionP. aeruginosaSurgical intensive care unitPositive clinical cultureCare unit admissionEmpirical antibiotic therapyTertiary care hospitalType of ICUSignificant risk factorsP. aeruginosa colonizationRapid diagnostic testingPerirectal surveillance culturesUnit admissionCohort studyAntibiotic therapyCare hospitalClinical outcomes
2006
Predictors for Haemophilus influenzae Colonization, Antibiotic Resistance and for Sharing an Identical Isolate Among Children Attending 16 Licensed Day-Care Centers in Michigan
Barbosa-Cesnik C, Farjo RS, Patel M, Gilsdorf J, McCoy SI, Pettigrew MM, Marrs C, Foxman B. Predictors for Haemophilus influenzae Colonization, Antibiotic Resistance and for Sharing an Identical Isolate Among Children Attending 16 Licensed Day-Care Centers in Michigan. The Pediatric Infectious Disease Journal 2006, 25: 219-223. PMID: 16511383, DOI: 10.1097/01.inf.0000202130.78540.28.Peer-Reviewed Original ResearchConceptsDay care centersH. influenzae colonizationNontypable H. influenzaeH. influenzaeOtitis mediaColonized childrenAntibiotic resistanceLicensed day care centersSame day care centerHaemophilus influenzae colonizationModifiable risk factorsRisk factor questionnaireH. influenzae isolatesNontypable Haemophilus influenzaeDay care center directorsIdentical isolatesInfluenzae isolatesPacifier useThroat swabsHygiene habitsRisk factorsTobacco smokeImportant causeHaemophilus influenzaeOverall colonization rate