Streptococcus pneumoniae biofilm formation and dispersion during colonization and disease
Chao Y, Marks LR, Pettigrew MM, Hakansson AP. Streptococcus pneumoniae biofilm formation and dispersion during colonization and disease. Frontiers In Cellular And Infection Microbiology 2015, 4: 194. PMID: 25629011, PMCID: PMC4292784, DOI: 10.3389/fcimb.2014.00194.Peer-Reviewed Original ResearchConceptsNasopharyngeal environmentConcomitant virus infectionPneumococcal biofilmsMiddle ear infectionRespiratory epithelial cellsMillions of infectionsPneumococcal biofilm formationPneumococcal diseaseEar infectionsSterile sitesInvasive diseasePneumococcal colonizationHigh prevalenceVirus infectionDisease processDistinct phenotypic propertiesMucosal surfacesStreptococcus pneumoniaeVaccine escapeHuman nasopharynxDiseaseEpithelial cellsInfectionPneumococciAntibiotic resistance