Association of relative dose intensity with BMI and pathologic complete response in patients treated with neoadjuvant chemotherapy for breast cancer
Usiskin I, Li F, Irwin ML, Cartmel B, Sanft T. Association of relative dose intensity with BMI and pathologic complete response in patients treated with neoadjuvant chemotherapy for breast cancer. Breast Cancer Research And Treatment 2020, 186: 191-197. PMID: 33125620, DOI: 10.1007/s10549-020-05994-8.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAntineoplastic Combined Chemotherapy ProtocolsBody Mass IndexBreast NeoplasmsCohort StudiesFemaleHumansMiddle AgedNeoadjuvant TherapyRetrospective StudiesTreatment OutcomeConceptsRelative dose intensityPathologic complete responseNeoadjuvant chemotherapyBreast cancerDose reductionDose intensityComplete responseLower BMIHigh relative dose intensityDose delaysTreatment tolerabilityPatient adherenceTreatment delayTumor characteristicsCancer HospitalChemotherapy dosesHigher BMIRetrospective studyResultsOur cohortMedical recordsPurposePrevious workChi-square analysisBMICommon reasonAverage age