2022
Adipose tissue radiodensity and mortality among patients with nonmetastatic breast cancer
Cheng E, Caan BJ, Chen WY, Irwin ML, Prado CM, Cespedes Feliciano EM. Adipose tissue radiodensity and mortality among patients with nonmetastatic breast cancer. Clinical Nutrition 2022, 41: 2607-2613. PMID: 36306565, PMCID: PMC9722634, DOI: 10.1016/j.clnu.2022.09.016.Peer-Reviewed Original ResearchConceptsNonmetastatic breast cancerVisceral adipose tissueBreast cancerBreast cancer prognosisOverall mortalitySpecific mortalityAdipose tissueCancer prognosisTissue radiodensityMultivariable Cox proportional hazards regressionKaiser Permanente Northern CaliforniaCox proportional hazards regressionRole of adiposityBody mass indexProportional hazards regressionBreast cancer survivalNovel prognostic markerThird lumbar vertebraIntegrated healthcare systemNon-Hispanic whitesMultiple cancer typesHazard ratioNonmetastatic patientsPrognostic factorsClinicopathological characteristics
2009
Exercise Improves Body Fat, Lean Mass, and Bone Mass in Breast Cancer Survivors
Irwin ML, Alvarez‐Reeves M, Cadmus L, Mierzejewski E, Mayne ST, Yu H, Chung GG, Jones B, Knobf MT, DiPietro L. Exercise Improves Body Fat, Lean Mass, and Bone Mass in Breast Cancer Survivors. Obesity 2009, 17: 1534-1541. PMID: 19629060, PMCID: PMC2841468, DOI: 10.1038/oby.2009.18.Peer-Reviewed Original ResearchConceptsModerate-intensity aerobic exerciseUsual care participantsBreast cancer survivorsMin/weekDual-energy X-ray absorptiometryUsual care groupBone mineral densityCancer survivorsAerobic exerciseCare participantsLean massBody fatBody compositionCare groupBone massYale-New Haven Hospital Tumor RegistryPostmenopausal breast cancer survivorsCurrent physical activity levelsHospital tumor registryAerobic exercise interventionPhysical activity levelsBreast cancer prognosisPercent body fatX-ray absorptiometryBreast cancer diagnosis
2005
Changes in Body Fat and Weight After a Breast Cancer Diagnosis: Influence of Demographic, Prognostic, and Lifestyle Factors
Irwin ML, McTiernan A, Baumgartner RN, Baumgartner KB, Bernstein L, Gilliland FD, Ballard-Barbash R. Changes in Body Fat and Weight After a Breast Cancer Diagnosis: Influence of Demographic, Prognostic, and Lifestyle Factors. Journal Of Clinical Oncology 2005, 23: 774-782. PMID: 15681521, PMCID: PMC3000612, DOI: 10.1200/jco.2005.04.036.Peer-Reviewed Original ResearchConceptsBody fat changesBody fatBreast cancer diagnosisLifestyle factorsPhysical activityFat changesCancer diagnosisHigher disease stagePopulation-based studyBreast cancer recurrenceBreast cancer prognosisPercent body fatFirst yearLean womenObese womenBaseline visitPotential cofoundersDisease stageLifestyle StudyPostdiagnosis periodCancer recurrenceBreast cancerCancer prognosisFat lossYounger age
2003
Effect of Exercise on Total and Intra-abdominal Body Fat in Postmenopausal Women: A Randomized Controlled Trial
Irwin ML, Yasui Y, Ulrich CM, Bowen D, Rudolph RE, Schwartz RS, Yukawa M, Aiello E, Potter JD, McTiernan A. Effect of Exercise on Total and Intra-abdominal Body Fat in Postmenopausal Women: A Randomized Controlled Trial. JAMA 2003, 289: 323-330. PMID: 12525233, DOI: 10.1001/jama.289.3.323.Peer-Reviewed Original ResearchMeSH KeywordsAbdomenAdipose TissueAgedBody CompositionBody Mass IndexExerciseFemaleHumansMiddle AgedObesityPostmenopauseWeight LossConceptsSubcutaneous abdominal fatBody fat lossEffects of exercisePostmenopausal womenBody fatBody weightHome-based moderate-intensity exerciseAbdominal fatFat lossGreater body fat lossMajor public health concernSports/recreational activitiesObese postmenopausal womenIntra-abdominal fatPrevalence of obesityReduced body weightDuration of exerciseMin/wkModerate-intensity exerciseSignificant dose responseTotal body fatLevel of exerciseTwelve-month dataPublic health concernExercise group