2009
Randomized Controlled Trial of Aerobic Exercise on Insulin and Insulin-like Growth Factors in Breast Cancer Survivors: The Yale Exercise and Survivorship Study
Irwin ML, Varma K, Alvarez-Reeves M, Cadmus L, Wiley A, Chung GG, DiPietro L, Mayne ST, Yu H. Randomized Controlled Trial of Aerobic Exercise on Insulin and Insulin-like Growth Factors in Breast Cancer Survivors: The Yale Exercise and Survivorship Study. Cancer Epidemiology Biomarkers & Prevention 2009, 18: 306-313. PMID: 19124513, PMCID: PMC2841479, DOI: 10.1158/1055-9965.epi-08-0531.Peer-Reviewed Original ResearchConceptsBreast cancer survivorsPostmenopausal breast cancer survivorsModerate-intensity aerobic exerciseUsual care groupBreast cancer riskAerobic exerciseIGFBP-3Cancer survivorsUsual careCare groupCancer riskYale-New Haven Hospital Tumor RegistryCurrent physical activity levelsInsulin-like growth factorHospital tumor registryUsual care participantsAerobic exercise interventionExercise-induced decreasePhysical activity levelsInsulin-like growthExercise groupExercise interventionControlled TrialsTumor RegistryBrisk walking
2008
Impact of Nutrition and Exercise on Cancer Survival
Irwin ML, Mayne ST. Impact of Nutrition and Exercise on Cancer Survival. The Cancer Journal 2008, 14: 435-441. PMID: 19060611, DOI: 10.1097/ppo.0b013e31818daeee.Peer-Reviewed Original ResearchConceptsCancer survivorsSupplement useCancer survivalAdverse prognostic factorPhysical activity recommendationsNutrient supplement useAmerican Cancer SocietyLifestyle-based approachLong-term survivalImpact of nutritionLifestyle interventionPrognostic factorsRandomized trialsCancer outcomesPhysical inactivityActivity recommendationsCurrent guidelinesNumber of menCancer SocietyPhysical activityWeight gainAvailable evidenceSurvivorsSurvivalObesityInfluence of Pre- and Postdiagnosis Physical Activity on Mortality in Breast Cancer Survivors: The Health, Eating, Activity, and Lifestyle Study
Irwin ML, Smith AW, McTiernan A, Ballard-Barbash R, Cronin K, Gilliland FD, Baumgartner RN, Baumgartner KB, Bernstein L. Influence of Pre- and Postdiagnosis Physical Activity on Mortality in Breast Cancer Survivors: The Health, Eating, Activity, and Lifestyle Study. Journal Of Clinical Oncology 2008, 26: 3958-3964. PMID: 18711185, PMCID: PMC2654316, DOI: 10.1200/jco.2007.15.9822.Peer-Reviewed Original ResearchConceptsPhysical activityBreast cancerHazard ratioLifestyle StudyTotal deathsModerate-intensity physical activityMultivariable hazard ratiosPostdiagnosis physical activityProspective observational studyBreast cancer deathsBreast cancer survivorsMetabolic equivalent hoursRegional breast cancerPostdiagnosis changesPrimary outcomeCancer survivorsPrimary exposureCancer deathInactive womenObservational studyLower riskGreater riskDiagnosisInfluence of preWomen
2005
Relationship of Obesity and Physical Activity with C-Peptide, Leptin, and Insulin-Like Growth Factors in Breast Cancer Survivors
Irwin ML, McTiernan A, Bernstein L, Gilliland FD, Baumgartner R, Baumgartner K, Ballard-Barbash R. Relationship of Obesity and Physical Activity with C-Peptide, Leptin, and Insulin-Like Growth Factors in Breast Cancer Survivors. Cancer Epidemiology Biomarkers & Prevention 2005, 14: 2881-2888. PMID: 16365005, PMCID: PMC3000615, DOI: 10.1158/1055-9965.epi-05-0185.Peer-Reviewed Original ResearchConceptsInsulin-like growth factorBreast cancer survivorsBody mass indexPhysical activityC-peptideMass indexCancer survivorsInactive breast cancer patientsLow IGF-I levelsIGF-binding protein-3Growth factorHigher C-peptideIIIA breast cancerIGF-I levelsRelationship of obesityLower C-peptideBreast cancer patientsInterview-administered questionnairePhysical activity categoriesBreast cancer prognosisPopulation-based sampleHormones/peptidesLeptin levelsHigher IGFCancer patients
2004
Physical activity levels among breast cancer survivors.
Irwin ML, McTiernan A, Bernstein L, Gilliland FD, Baumgartner R, Baumgartner K, Ballard-Barbash R. Physical activity levels among breast cancer survivors. Medicine & Science In Sports & Exercise 2004, 36: 1484-91. PMID: 15354027, PMCID: PMC3000611.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBreast NeoplasmsEthnicityExerciseFemaleHumansMiddle AgedSurvivorsUnited StatesConceptsBreast cancer survivorsHispanic breast cancer survivorsLevel of PACancer survivorsPhysical activityWeight gainBlack breast cancer survivorsObese breast cancer survivorsSurveillance Epidemiology End ResultsPostdiagnosis weight gainNegative prognostic factorBreast cancer survivalRecreational physical activityPhysical activity levelsGeneral adult populationBreast cancer prognosisNon-Hispanic whitesCategories of adiposityPrognostic factorsType of sportDisease stageCancer survivalLifestyle StudyBreast cancerPA recommendations