Pilot study of combined aerobic and resistance exercise on fatigue for patients with head and neck cancer: Inflammatory and epigenetic changes
Xiao C, Beitler JJ, Higgins KA, Chico CE, Withycombe JS, Zhu Y, Zhao H, Lin IH, Li F, Jeon S, Irwin M, Bruner DW, Miller AH, Gary R. Pilot study of combined aerobic and resistance exercise on fatigue for patients with head and neck cancer: Inflammatory and epigenetic changes. Brain Behavior And Immunity 2020, 88: 184-192. PMID: 32330594, PMCID: PMC7415514, DOI: 10.1016/j.bbi.2020.04.044.Peer-Reviewed Original ResearchConceptsExercise groupInflammatory markersChair standNeck cancerBiceps curlSoluble TNF receptor IIMultidimensional Fatigue Inventory-20Tumor necrosis factor αPilot studyResistance exercise interventionTNF receptor IIPlasma interleukin-6Anti-inflammatory effectsC-reactive proteinPhysical function measuresIL1 receptor antagonistHand grip strengthNecrosis factor αIntensity-modulated radiotherapyStandard careExercise interventionWalk distanceRadiotherapy regimenHNC patientsMean age