2010
Fasting C-Peptide Levels and Death Resulting From All Causes and Breast Cancer: The Health, Eating, Activity, and Lifestyle Study
Irwin ML, Duggan C, Wang CY, Smith AW, McTiernan A, Baumgartner RN, Baumgartner KB, Bernstein L, Ballard-Barbash R. Fasting C-Peptide Levels and Death Resulting From All Causes and Breast Cancer: The Health, Eating, Activity, and Lifestyle Study. Journal Of Clinical Oncology 2010, 29: 47-53. PMID: 21115859, PMCID: PMC3055859, DOI: 10.1200/jco.2010.28.4752.Peer-Reviewed Original ResearchConceptsC-peptide levelsRisk of deathType 2 diabetesBreast cancerHazard ratioLifestyle StudyC-peptideDietary-induced weight lossSerum C-peptideCox regression analysisBody mass indexRegional breast cancerBreast cancer diagnosisMass indexInsulin secretionTreatment strategiesObservational studyEstrogen receptorPhysical activityCancerWeight lossCancer diagnosisCertain subgroupsWomenDeath
2005
Relationship of Obesity and Physical Activity with C-Peptide, Leptin, and Insulin-Like Growth Factors in Breast Cancer Survivors
Irwin ML, McTiernan A, Bernstein L, Gilliland FD, Baumgartner R, Baumgartner K, Ballard-Barbash R. Relationship of Obesity and Physical Activity with C-Peptide, Leptin, and Insulin-Like Growth Factors in Breast Cancer Survivors. Cancer Epidemiology Biomarkers & Prevention 2005, 14: 2881-2888. PMID: 16365005, PMCID: PMC3000615, DOI: 10.1158/1055-9965.epi-05-0185.Peer-Reviewed Original ResearchConceptsInsulin-like growth factorBreast cancer survivorsBody mass indexPhysical activityC-peptideMass indexCancer survivorsInactive breast cancer patientsLow IGF-I levelsIGF-binding protein-3Growth factorHigher C-peptideIIIA breast cancerIGF-I levelsRelationship of obesityLower C-peptideBreast cancer patientsInterview-administered questionnairePhysical activity categoriesBreast cancer prognosisPopulation-based sampleHormones/peptidesLeptin levelsHigher IGFCancer patients