Association between Organophosphate Ester Exposure and Insulin Resistance with Glycometabolic Disorders among Older Chinese Adults 60–69 Years of Age: Evidence from the China BAPE Study
Ding E, Deng F, Fang J, Li T, Hou M, Liu J, Miao K, Yan W, Fang K, Shi W, Fu Y, Liu Y, Dong H, Dong L, Ding C, Liu X, Pollitt K, Ji J, Shi Y, Cai Y, Tang S, Shi X. Association between Organophosphate Ester Exposure and Insulin Resistance with Glycometabolic Disorders among Older Chinese Adults 60–69 Years of Age: Evidence from the China BAPE Study. Environmental Health Perspectives 2023, 131: 047009. PMID: 37042841, PMCID: PMC10094192, DOI: 10.1289/ehp11896.Peer-Reviewed Original ResearchMeSH KeywordsAgedChinaDiabetes Mellitus, Type 2East Asian PeopleEstersFlame RetardantsHumansInsulin ResistanceMiddle AgedOrganophosphatesPhosphatesConceptsYears of ageOPE exposureAdults 60OPE metabolitesCommon endocrine-disrupting chemicalsChina BAPE studySubsequent key eventsType 2 diabetesExposure reduction strategiesAdverse outcome pathwaysDiabetogenic effectInsulin resistanceUrine metabolomeElevated riskEster exposureParticipants 60Endocrine-disrupting chemicalsBlood transcriptomeAdverse effectsGlycometabolic disordersBiological etiologyAgeT2DMulti-omics analysisMarkers