2023
Daily Summer Temperatures and Hospitalization for Acute Cardiovascular Events: Impact of Outdoor PM2.5 Oxidative Potential on Observed Associations Across Canada
Weichenthal S, Lavigne E, You H, Pollitt K, Shin T, Kulka R, Stieb D, Hatzopoulou M, Evans G, Burnett R. Daily Summer Temperatures and Hospitalization for Acute Cardiovascular Events: Impact of Outdoor PM2.5 Oxidative Potential on Observed Associations Across Canada. Epidemiology 2023, 34: 897-905. PMID: 37732880, DOI: 10.1097/ede.0000000000001651.Peer-Reviewed Original ResearchConceptsIschaemic heart disease eventsHeart disease eventsAcute cardiovascular eventsCardiovascular eventsDisease eventsOdds ratioPotential time-varying confoundersAcute cardiovascular effectsFine particulate air pollutionCase-crossover studyOutdoor fine particulate air pollutionHealth impactsCardiovascular health impactsParticulate air pollutionCardiovascular effectsHighest tertileTime-varying confoundersOlder subjectsHospitalizationObserved associationsOxidative stressOxidative potentialPM2.5 oxidative potentialMonthsAssociation
2021
Association of Sulfur, Transition Metals, and the Oxidative Potential of Outdoor PM2.5 with Acute Cardiovascular Events: A Case-Crossover Study of Canadian Adults
Weichenthal S, Lavigne E, Traub A, Umbrio D, You H, Pollitt K, Shin T, Kulka R, Stieb DM, Korsiak J, Jessiman B, Brook JR, Hatzopoulou M, Evans G, Burnett RT. Association of Sulfur, Transition Metals, and the Oxidative Potential of Outdoor PM2.5 with Acute Cardiovascular Events: A Case-Crossover Study of Canadian Adults. Environmental Health Perspectives 2021, 129: 107005. PMID: 34644144, PMCID: PMC8513754, DOI: 10.1289/ehp9449.Peer-Reviewed Original ResearchConceptsAcute cardiovascular eventsCardiovascular eventsCase-crossover studyOdds ratioConditional logistic regression modelsFine particulate air pollutionLogistic regression modelsParticulate air pollutionStrength of associationCanadian adultsPopulation health risksObserved associationsRecent evidenceWeak associationOxidative potentialHealth impactsMenAssociationHealth risksMedian valueRegression modelsInfluence associationsAssociated health impactsSimilar patternOutdoor PM2.5Predicting Spatial Variations in Multiple Measures of Oxidative Burden for Outdoor Fine Particulate Air Pollution across Canada
Xu JW, Martin RV, Evans GJ, Umbrio D, Traub A, Meng J, van Donkelaar A, You H, Kulka R, Burnett RT, Pollitt K, Weichenthal S. Predicting Spatial Variations in Multiple Measures of Oxidative Burden for Outdoor Fine Particulate Air Pollution across Canada. Environmental Science And Technology 2021, 55: 9750-9760. PMID: 34241996, DOI: 10.1021/acs.est.1c01210.Peer-Reviewed Original Research