About
Copy Link
Titles
Professor Adjunct
Biography
Jean Bosco Ouedraogo is a MD, parasitologist and Researcher with a distinguished scientific career with major contributions to science in Burkina Faso. He is also a Professor of parasitology at the universities of Ouagadougou and Bobo-Dioulasso. Since 1983, He have conducted a series of studies on the resistance to different antimalarial drugs using in vivo, in vitro and molecular techniques. Recently he participated and played an important role in the RTS,S malaria vaccine trial in Burkina. He is currently investigating the potential benefit of adding azithromycin to the antimalarials used for SMC and a comparative study of SMC and seasonal vaccination with RTSS. He is also PI of many ongoing clinical trials and vaccine trials in the region of Bobo-Dioulasso, Burkina Faso.
His scientific contributions have been presented in over 185 peer reviewed publications.
In addition to the scientific activities he has had substantial administrative responsibilities acting as director of Institut de Recherche en Sciences de la Santé (IRSS) in Bobo-Dioulasso from 1999-2015 and Director General of the Centre Muraz from 2009 -2013.
He is currently:
- Head of Malaria & Neglected Tropical Diseases Unit, IRSS
- Director General of INSTech, Bobo-Dioulasso
- Executive secretary of WAHRNET (West African Health Research Network)
Last Updated on April 07, 2025.
Appointments
Epidemiology of Microbial Diseases
Professor AdjunctPrimary
Other Departments & Organizations
- All Institutions
- Epidemiology of Microbial Diseases
- Yale School of Public Health
Research
Copy Link
Overview
Public Health Interests
COVID-19; Disease Transmission; Emerging Infectious Diseases; Enteric Diseases; Clinical Trials; Community Engagement; Health Policy; Capacity Building; Epidemiology Methods; Ethics; Genetics, Genomics, Epigenetics; Health Economics; Tick-borne Diseases; Trypanosomiasis; HIV/AIDS; Immunology; Implementation Science; Infectious Diseases; Influenza; Malaria; Maternal & Child Health; Microbiome; Mosquito-borne Diseases; Neglected Tropical Diseases; Non-Communicable Diseases; Parasitology; Randomized Trials; Antimicrobial Resistance; Vaccines; Vector Biology; Vector-borne Diseases; Viruses; Zoonotic Diseases
ORCID
0000-0003-0412-8733
Research at a Glance
Yale Co-Authors
Frequent collaborators of Jean Bosco Ouedraogo's published research.
Publications Timeline
A big-picture view of Jean Bosco Ouedraogo's research output by year.
Sunil Parikh, MD, MPH
Amy Bei, PhD
Joseph Vinetz, MD, FACP, FIDSA, FASTMH, BS
Martina Wade
Adam V Wisnewski, PhD, D(ABMLI)
Akiko Iwasaki, PhD
256Publications
11,023Citations
Publications
2025
Evaluation de la capacité antiplasmodiale in vivo d’un phytomédicament à base de 7 plantes médicinales « YIKI »
Kabre Z, Yerbanga R, Koama B, GNANOU Y, Kam S, Zongo E, Ouedraogo G, Ouedraogo J, Meda R. Evaluation de la capacité antiplasmodiale in vivo d’un phytomédicament à base de 7 plantes médicinales « YIKI ». Sciences De La Santé 2025, 48: 205-222. DOI: 10.64707/revstss.v48i2.1992.Peer-Reviewed Original ResearchPerformance characteristics and potential public health impact of improved pre-erythrocytic malaria vaccines targeting childhood burden
Malinga J, Braunack-Mayer L, Masserey T, Cavelan A, Chandramohan D, Dicko A, Ouédraogo J, Kelly S, Le Rutte E, Nekkab N, Penny M. Performance characteristics and potential public health impact of improved pre-erythrocytic malaria vaccines targeting childhood burden. PLOS Global Public Health 2025, 5: e0004549. PMID: 40758687, PMCID: PMC12321141, DOI: 10.1371/journal.pgph.0004549.Peer-Reviewed Original ResearchCitationsAltmetricConceptsPre-erythrocytic vaccineMalaria vaccineChildhood malariaDuration of protectionIndividual-based model of malaria transmissionPre-erythrocytic malaria vaccineModel of malaria transmissionMalaria vaccine developmentRTS,SSevere childhood malariaRTS,S/AS01Public health impactIncidence reductionRoutine immunization programSeasonal vaccineMalaria transmissionClinical endpointsPotential public health impactVaccine efficacyPrimary vaccinationYear boosterMalariaVaccine developmentVaccine propertiesTrial data95 Assessing genetic diversity of the Pfs25 vaccine candidate: Implications for malaria transmission-blocking vaccine in Africa
Orfano A, Cisse A, Sheng Z, Guo Y, Han L, Thiam L, Mangou K, Moore A, Ba A, Li R, Pouye M, Diallo F, Sene S, Ngom E, Sadio B, Mbengue A, Membi C, Bazié T, Somé F, Olson N, Patel S, Shapiro L, Parikh S, Foy B, Cappello M, Premji Z, Dabiré R, Ouedraogo J, Bei A. 95 Assessing genetic diversity of the Pfs25 vaccine candidate: Implications for malaria transmission-blocking vaccine in Africa. Journal Of Clinical And Translational Science 2025, 9: 29-29. PMCID: PMC12050472, DOI: 10.1017/cts.2024.767.Peer-Reviewed Original ResearchConceptsSingle nucleotide polymorphismsTransmission-blocking vaccinesGenetic diversityComplex infectionSymptomatic P. falciparum infectionsMalaria transmission-blocking vaccineVaccine candidatesVariant frequenciesNovel single nucleotide polymorphismsNonsynonymous single nucleotide polymorphismsRare variantsFrequency of single nucleotide polymorphismsP. falciparum 3D7Plasmodium falciparum samplesAmplicon deep sequencingMalaria eliminationCountry-specific prevalenceEndemic African countriesPfs25 proteinGeneious softwareParasite genetic diversityProportion of mutant allelesAmplicon sequencingPfs25Mutant allelesThe anti-circumsporozoite antibody response to repeated, seasonal booster doses of the malaria vaccine RTS,S/AS01E
Ali M, Stockdale L, Sagara I, Zongo I, Yerbanga R, Mahamar A, Nikièma F, Tapily A, Sompougdou F, Diarra M, Bellamy D, Provstgaard-Morys S, Zoungrana C, Issiaka D, Haro A, Sanogo K, Sienou A, Kaya M, Traore S, Dicko O, Kone Y, Yalcouye H, Thera I, Diarra K, Snell P, Ofori-Anyinam O, Ockenhouse C, Lee C, Ewer K, Tinto H, Djimde A, Ouedraogo J, Dicko A, Chandramohan D, Greenwood B. The anti-circumsporozoite antibody response to repeated, seasonal booster doses of the malaria vaccine RTS,S/AS01E. Npj Vaccines 2025, 10: 26. PMID: 39915506, PMCID: PMC11802723, DOI: 10.1038/s41541-025-01078-0.Peer-Reviewed Original ResearchCitationsAltmetricConceptsDoses of RTS,S/AS01RTS,S/AS01Dose of vaccineBooster dose of vaccineBooster doseAntibody responseCircumsporozoite proteinMalaria-endemic areas of AfricaRTS,S/AS01E malaria vaccineAnti-CSP antibody responsesAntibody titresBurden of malariaMalaria transmission seasonMalaria-endemic areasAnti-CSP antibodiesPlasmodium falciparum sporozoitesRisk of malariaMalaria vaccine RTS,S/AS01Incidence of malariaAssociated with protectionMultiplex assayYears of ageSevere malariaMalaria vaccineS/AS01Traditional Uses of Seven Medicinal Plants for Malaria Treatment in Bobo-Dioulasso, Burkina Faso
Zachari K, Serge Y, Nâg-Tiero M, Alassane H, Aminata F, Eric K, Eliasse Z, Kouliga K, Hadidjatou B, Windmi K, Yempabou O, Fabrice S, Anicet O, Jean-Bosco O. Traditional Uses of Seven Medicinal Plants for Malaria Treatment in Bobo-Dioulasso, Burkina Faso. Advances In Infectious Diseases 2025, 15: 79-95. DOI: 10.4236/aid.2025.151007.Peer-Reviewed Original ResearchConceptsMalaria treatmentRoot decoctionMalaria knowledgeMalaria symptomsBobo-DioulassoAntimalarial drugsMalariaC. planchoniiA. leiocarpusC. sieberianaLeaves decoctionT. emeticaMedicinal plantsTreatmentSocio-demographic profileHealth facilitiesEthnomedical usesPharmacological investigationsDecoctionS. longepedunculataX. americanaZ. zanthoxyloidesTraditional healersFrequency of plant useIn vivo toxicity of essential oils of two medicinal plants from Burkina Faso: Hyptis spicigera Lam. and Ocimum americanum L.
Ouedraogo W, Yerbanga R, Boni I, Koama B, Meda R, Ouedraogo J, Ouedraogo G. In vivo toxicity of essential oils of two medicinal plants from Burkina Faso: Hyptis spicigera Lam. and Ocimum americanum L. 2025, 13: 27-39. DOI: 10.37745/irjns.13/vol13n12739.Peer-Reviewed Original ResearchConceptsEssential oilAcute oral toxicityToxicity of essential oilsCorn oilAnimal weight gainOral toxicityIn vivo toxicityHyptis spicigera LamOcimum americanumHyptis spicigeraBurkina FasoO. americanumStatistical differenceBlood parametersOrgan weightsWeight gainMedicinal plantsCutaneous toxicityCornFollow-upNMRI miceWistar ratsDraize scoresBlood samplesControl group
2024
Cohort profile: the WHO Child Mortality Risk Stratification Multi-Country Pooled Cohort (WHO-CMRS) to identify predictors of mortality through early childhood
Schwinger C, Kaldenbach S, Berkley J, Walson J, Argaw A, Chowdhury R, Strand T, Rollins N, Ahmed T, Alemayehu A, Rajiv B, Jeanette B, Abdullah B, Elodie B, Berkley J, Kenneth B, Jobayer C, Ranadip C, Hama D, Christopher A, Denise E, Wafaie F, Ameena G, Ousmane G, Rebecca G, David H, Sonja H, Lieven H, Sheila I, Fyezah J, Jerome K, Patrick K, Siri K, Marko K, Alfazal K, Rasheda K, Niranjan K, Sengchanh K, Carl L, Lacey L, Agnes L, Natasha L, Jef L, Mustafa M, Mark M, Karim P, Sam M, Marie M, Raghava M, Sophie M, Kenya M, Ezekiel M, Shalton M, Bin N, Kulandaipalayam N, Moses N, Imran N, Deanna O, Jean-Bosco O, Andrew P, Audrey P, Dominique R, Peter R, Nigel R, Marie R, Ali S, Sunil S, Catherine S, Benson S, Heather S, Strand T, Molly T, Céline T, Indi T, Geeta T, Wieger V, Judd L, Donqing W, Ali W, Matthew W, Tahmeed A, Alemayehu A, Bahl R, Bailey J, Baqui A, Becquey E, Berkley J, Brown K, Chisti M, Chowdhury R, Diallo H, Duggan C, Evans D, Fawzi W, Khan A, Goga A, Guindo O, Grais R, Hamer D, Hess S, Huybregts L, Isanaka S, Jehan F, Kabakyenga J, Kabore P, Kaldenbach S, Kerac M, Khanam R, Kissoon N, Kounnavong S, Lachat C, LaGrone L, Le Port A, Lelijveld N, Leroy J, Mahfuz M, Kenneth M, Manary M, Manji K, Marconi S, McGrath M, Mohan V, Moore S, Mugisha N, Mupere E, Mwaringa S, Bin Nisar Y, Natarajan S, Ngari M, Nisar I, Olney D, Ouedraogo J, Prentice A, Prost A, Roberfroid D, Rockers P, Rollins N, Ruel M, Saleem A, Sazawal S, Schwinger C, Singa B, Stobaugh H, Strand T, Sunita T, Timbwa M, Toe L, Trehan I, Trilok-Kumar G, Voskuijl W, Walson J, Wang D, Waseem A, Wiens M, Ahmed T, Argaw A, Bahl R, Bailey J, Baqui A, Becquey E, Berkley J, Brown K, Chisti M, Chowdhury R, Diallo H, Duggan C, Evans D, Fawzi W, Khan A, Goga A, Guindo O, Grais R, Hamer D, Hess S, Huybregts L, Isanaka S, Jehan F, Kabakyenga J, Kabore P, Kaldenbach S, Kerac M, Khanam R, Kissoon N, Kounnavong S, Lachat C, LaGrone L, Le Port A, Lelijveld N, Leroy J, Mahfuz M, Manary M, Manji K, Marconi S, McGrath M, Mohan V, Moore S, Mugisha N, Mupere E, Mwaringa S, Bin Nisar Y, Natarajan S, Ngari M, Nisar I, Olney D, Ouedraogo J, Prentice A, Prost A, Roberfroid D, Rockers P, Rollins N, Ruel M, Saleem A, Sazawal S, Schwinger C, Singa B, Stobaugh H, Strand T, Timbwa M, Toe L, Trehan I, Trilok-Kumar G, Voskuijl W, Walson J, Wang D, Ali W, Wiens M. Cohort profile: the WHO Child Mortality Risk Stratification Multi-Country Pooled Cohort (WHO-CMRS) to identify predictors of mortality through early childhood. BMJ Open 2024, 14: e085164. PMID: 39613436, PMCID: PMC11605845, DOI: 10.1136/bmjopen-2024-085164.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsBirth weightAcute lower respiratory tract infectionStudy visitsLower respiratory tract infectionsMiddle-income countriesMedian study periodClinical management toolLow birth weightRespiratory tract infectionsProportion of childrenPredictors of mortalityHealth facilitiesHealthcare settingsCommunity settingsYears of ageBirth characteristicsMonths of ageFeeding practicesGestational ageIntervention studiesMortality riskPreterm birthTract infectionsChild ageAcute diarrheaTraditional Healer’s Medicinal Practice Survey and Clinical Evidence Assessment of “YIKI”: An Antimalarial Phytomedicine Recipe from Bobo-Dioulasso, Burkina Faso
Zachari K, Serge Y, Aminata F, Nâg-Tiero M, Fabrice S, Alassane H, A. B, B. Y, Kouliga K, Eric K, Eliasse Z, Hadidjatou B, Windmi K, Florence F, A. O, Jean-Bosco O. Traditional Healer’s Medicinal Practice Survey and Clinical Evidence Assessment of “YIKI”: An Antimalarial Phytomedicine Recipe from Bobo-Dioulasso, Burkina Faso. Pharmacology & Pharmacy 2024, 15: 248-267. DOI: 10.4236/pp.2024.157015.Peer-Reviewed Original ResearchCitationsConceptsPhysical examinationKnowledge of malaria symptomsUncomplicated malaria treatmentPhysical examination of patientsExamination of patientsMalaria knowledgeMalaria diagnosisMalaria casesMalaria symptomsDose adjustmentMalaria treatmentBobo-DioulassoElimination of parasitesHemoglobin levelsClinical evidenceThin blood smearsAntimalarial phytomedicineMalariaPatientsComplete curePatient treatmentToxicity studiesBlood smearsParasitaemiaEvidence assessmentA simple, field-applicable method to increase the infectivity of wild isolates of Plasmodium falciparum to mosquito vectors
Ouattara S, Hien D, Nao E, Paré P, Guissou E, Cohuet A, Morlais I, Yerbanga R, Dabiré K, Ouédraogo J, Mouline K, Lefèvre T. A simple, field-applicable method to increase the infectivity of wild isolates of Plasmodium falciparum to mosquito vectors. Malaria Journal 2024, 23: 135. PMID: 38711028, PMCID: PMC11075210, DOI: 10.1186/s12936-024-04969-0.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsDirect membrane feeding assaysGametocyte densityHuman-to-mosquito transmissionDonor bloodLow gametocyte densitiesMembrane feeding assaysPlasmodium falciparum gametocytesTransmission-blocking interventionsWhole bloodInfection rateFalciparum gametocytesInfectious reservoirNaive serumAsymptomatic individualsMosquito infectionHuman donorsRemoval of plasmaEndemic countriesSerumPlasmodiumParasite isolatesInfectionBlood treatmentGametocytesPlasma volumeEx vivo drug susceptibility and resistance mediating genetic polymorphisms of Plasmodium falciparum in Bobo-Dioulasso, Burkina Faso
Somé A, Conrad M, Kabré Z, Fofana A, Yerbanga R, Bazié T, Neya C, Somé M, Kagambega T, Legac J, Garg S, Bailey J, Ouédraogo J, Rosenthal P, Cooper R. Ex vivo drug susceptibility and resistance mediating genetic polymorphisms of Plasmodium falciparum in Bobo-Dioulasso, Burkina Faso. Antimicrobial Agents And Chemotherapy 2024, 68: e01534-23. PMID: 38411062, PMCID: PMC10989024, DOI: 10.1128/aac.01534-23.Peer-Reviewed Original ResearchCitationsConceptsResistance to antifolatesUncomplicated malariaEx vivo drug susceptibilityArtemisinin partial resistanceMonthly sulfadoxine-pyrimethaminePfcrt K76TPfK13 propeller domainResistance-mediating polymorphismsSeasonal malaria chemopreventionTreating uncomplicated malariaResistance to cycloguanilHigh-level resistancePlasmodium falciparumA581GA613S mutationsPfdhps mutationsPfmdr1 N86YArtemether-lumefantrineK76TSulfadoxine-pyrimethamineMalaria chemopreventionPrevent malariaBobo-DioulassoDrug susceptibilityPrincipal therapy
Academic Achievements & Community Involvement
Copy Link
Get In Touch
Copy Link