2016
Spatiotemporal calibration and resolution refinement of output from deterministic models
Gilani O, McKay LA, Gregoire TG, Guan Y, Leaderer BP, Holford TR. Spatiotemporal calibration and resolution refinement of output from deterministic models. Statistics In Medicine 2016, 35: 2422-2440. PMID: 26790617, DOI: 10.1002/sim.6867.Peer-Reviewed Original ResearchConceptsGrid-cell formatCurrent calibration techniquesSpatiotemporal calibrationModeling strategyCommunity Multiscale Air Quality (CMAQ) modelAir quality modelsMultiscale Air Quality modelCalibration techniqueObserved measurementsPixel sizeSpatial resolutionGrid dataMonitoring stationsQuality modelDeterministic modelRegular gridAmbient nitrogen dioxide concentrationsDaily estimatesMeasurementsProcess of interestGridNitrogen dioxide concentrationsProcessPixelsDioxide concentration
2013
Associations of PM2.5 Constituents and Sources with Hospital Admissions: Analysis of Four Counties in Connecticut and Massachusetts (USA) for Persons ≥ 65 Years of Age
Bell ML, Ebisu K, Leaderer BP, Gent JF, Lee HJ, Koutrakis P, Wang Y, Dominici F, Peng RD. Associations of PM2.5 Constituents and Sources with Hospital Admissions: Analysis of Four Counties in Connecticut and Massachusetts (USA) for Persons ≥ 65 Years of Age. Environmental Health Perspectives 2013, 122: 138-144. PMID: 24213019, PMCID: PMC3915260, DOI: 10.1289/ehp.1306656.Peer-Reviewed Original Research
2012
Relationship between birth weight and exposure to airborne fine particulate potassium and titanium during gestation
Bell ML, Belanger K, Ebisu K, Gent JF, Leaderer BP. Relationship between birth weight and exposure to airborne fine particulate potassium and titanium during gestation. Environmental Research 2012, 117: 83-89. PMID: 22705336, PMCID: PMC3418490, DOI: 10.1016/j.envres.2012.05.004.Peer-Reviewed Original ResearchConceptsLow birth weightBirth weightAdverse pregnancy outcomesPregnancy outcomesTerm infantsAirborne fine particulate matterStudy populationIQR increaseMothers' exposureAfrican American mothersFirst birthInfantsEffect estimatesConfidence intervalsWhite mothersPregnancyHealth impactsRiskExposureFine particulate matterMothersMost studiesGestationWeightEffects of Ambient Pollen Concentrations on Frequency and Severity of Asthma Symptoms Among Asthmatic Children
DellaValle CT, Triche EW, Leaderer BP, Bell ML. Effects of Ambient Pollen Concentrations on Frequency and Severity of Asthma Symptoms Among Asthmatic Children. Epidemiology 2012, 23: 55-63. PMID: 22082997, PMCID: PMC3246281, DOI: 10.1097/ede.0b013e31823b66b8.Peer-Reviewed Original ResearchConceptsShortness of breathRescue medication useAsthma maintenance medicationsMaintenance medicationPersistent coughSensitized childrenChest tightnessNight symptomsAsthmatic childrenMedication usePollen exposureSeverity of asthmaDaily respiratory symptomsWeed pollenLogistic regression analysisLow exposureSeparate logistic regression analysesAsthmatic symptomsRespiratory symptomsDaily symptomsAntibiotic useSymptom outcomesDaily ambientMedicationsAmbient pollen concentrations
2011
Urban land-use and respiratory symptoms in infants
Ebisu K, Holford TR, Belanger KD, Leaderer BP, Bell ML. Urban land-use and respiratory symptoms in infants. Environmental Research 2011, 111: 677-684. PMID: 21530957, PMCID: PMC3114197, DOI: 10.1016/j.envres.2011.04.004.Peer-Reviewed Original ResearchSpatial and temporal variability of fine particle composition and source types in five cities of Connecticut and Massachusetts
Lee HJ, Gent JF, Leaderer BP, Koutrakis P. Spatial and temporal variability of fine particle composition and source types in five cities of Connecticut and Massachusetts. The Science Of The Total Environment 2011, 409: 2133-2142. PMID: 21429560, PMCID: PMC3269973, DOI: 10.1016/j.scitotenv.2011.02.025.Peer-Reviewed Original ResearchConceptsPositive matrix factorizationSource contributionsSource typesTemporal variabilityRegional pollutionSource apportionment modelingLess spatial variabilityFine particle compositionRegional average concentrationsSea saltSpatial variabilityRegional averagePMF analysisMonitoring sitesOil combustionParticle compositionRoad dustAverage concentrationSite correlationsVariability
2010
Prenatal Exposure to Fine Particulate Matter and Birth Weight
Bell ML, Belanger K, Ebisu K, Gent JF, Lee HJ, Koutrakis P, Leaderer BP. Prenatal Exposure to Fine Particulate Matter and Birth Weight. Epidemiology 2010, 21: 884-891. PMID: 20811286, PMCID: PMC3055585, DOI: 10.1097/ede.0b013e3181f2f405.Peer-Reviewed Original Research
2009
Integrated exposure modeling: A model using GIS and GLM
Holford TR, Ebisu K, McKay LA, Gent JF, Triche EW, Bracken MB, Leaderer BP. Integrated exposure modeling: A model using GIS and GLM. Statistics In Medicine 2009, 29: 116-129. PMID: 19823976, PMCID: PMC3182125, DOI: 10.1002/sim.3732.Peer-Reviewed Original ResearchConceptsGeneralized linear modelLinear modelLayout of roadsDispersion functionStatistical modelStandard regression techniquesTraffic-related health effectsSecond examplePollutant dispersionSpline modelSpatial modelRegression techniquesDaily trafficConnecticut homesIntegralsModelTraffic densityDispersionGLMTrafficVariablesFunctionMeteorologyTraffic-related pollution
2001
Use of Health Services by Insurance Status Among Children With Asthma
Ortega A, Belanger K, Paltiel A, Horwitz S, Bracken M, Leaderer B. Use of Health Services by Insurance Status Among Children With Asthma. Medical Care 2001, 39: 1065-1074. PMID: 11567169, DOI: 10.1097/00005650-200110000-00004.Peer-Reviewed Original ResearchConceptsPrimary care visitsHealth care useEmergency departmentInsurance statusCare visitsAsthmatic childrenMedication useCare useAsthma-related risk factorsRoutine primary care visitsProspective cohort studyHealth care visitsHealth care utilizationChildhood asthma severityPatient-provider communicationWhite childrenMedical DictionaryNew England hospitalsRace/ethnicityAsthma specialistCohort studyMedicaid childrenAsthma severityIndependent predictorsCare utilizationRisk Factors for Asthma Prevalence Among Urban and Nonurban African American Children
von Maffei J, Beckett W, Belanger K, Triche E, Zhang H, Machung J, Leaderer B. Risk Factors for Asthma Prevalence Among Urban and Nonurban African American Children. Journal Of Asthma 2001, 38: 555-564. PMID: 11714078, DOI: 10.1081/jas-100107120.Peer-Reviewed Original ResearchConceptsRisk factorsUrban residenceAfrican American childrenMaternal cigarette smokingPhysician-diagnosed asthmaMultiple risk factorsYears of ageMaternal asthmaAsthmatic childrenAsthma prevalenceCigarette smokingAsthmaAmerican childrenAfrican American mothersIdentifiable factorsChildrenAmerican mothersResidenceFactorsSmokingAllergyNewbornsPrevalence
1999
Comparisons of seasonal fungal prevalence in indoor and outdoor air and in house dusts of dwellings in one Northeast American county1
REN P, JANKUN T, LEADERER B. Comparisons of seasonal fungal prevalence in indoor and outdoor air and in house dusts of dwellings in one Northeast American county1. Journal Of Exposure Science & Environmental Epidemiology 1999, 9: 560-568. PMID: 10638841, DOI: 10.1038/sj.jea.7500061.Peer-Reviewed Original ResearchConceptsHouse dust samplesSignificant differencesAdverse health effectsHealth effectsDust samplesHouse dustTypes of fungiConnecticut areaExposure assessmentBurkard portable air samplerIndoor air samplesSignificant changesFungal exposure assessmentNew HavenIndoor airMold concentrationsOutdoor airAllergyFungal prevalencePrevalenceEnvironmental Tobacco Smoke Exposure and Small-for-Gestational-Age Birth
Sadler L, Belanger K, Saftlas A, Leaderer B, Hellenbrand K, McSharry J, Bracken M. Environmental Tobacco Smoke Exposure and Small-for-Gestational-Age Birth. American Journal Of Epidemiology 1999, 150: 695-705. PMID: 10512423, DOI: 10.1093/oxfordjournals.aje.a010072.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge DistributionBirth WeightCohort StudiesConnecticutFemaleFetal Growth RetardationHumansInfant, NewbornInfant, Small for Gestational AgeInterviews as TopicLinear ModelsMaternal ExposureMultivariate AnalysisPregnancyPregnancy Trimester, ThirdProspective StudiesRetrospective StudiesRisk FactorsTobacco Smoke PollutionConceptsEnvironmental tobacco smoke exposureTobacco smoke exposureGestational-age birthsEnvironmental tobacco smokeSmoke exposureSGA birthThird trimesterTobacco smokeBirth weight differenceIntensity of exposureCohort studyMedian durationPostpartum interviewsUnexposed mothersUpper middle class groupBirth weightEffects of exposureFetal growthMultivariate logisticOdds ratioStudy populationLow levelsWomenBirthTrimesterIndoor, outdoor, and regional summer and winter concentrations of PM10, PM2.5, SO4(2)-, H+, NH4+, NO3-, NH3, and nitrous acid in homes with and without kerosene space heaters.
Leaderer B, Naeher L, Jankun T, Balenger K, Holford T, Toth C, Sullivan J, Wolfson J, Koutrakis P. Indoor, outdoor, and regional summer and winter concentrations of PM10, PM2.5, SO4(2)-, H+, NH4+, NO3-, NH3, and nitrous acid in homes with and without kerosene space heaters. Environmental Health Perspectives 1999, 107: 223-231. PMID: 10064553, PMCID: PMC1566377, DOI: 10.1289/ehp.99107223.Peer-Reviewed Original Research
1998
Correlates of Residential Wiring Code Used in Studies of Health Effects of Residential Electromagnetic Fields
Bracken M, Belanger K, Hellenbrand K, Addesso K, Patel S, Triche E, Leaderer B. Correlates of Residential Wiring Code Used in Studies of Health Effects of Residential Electromagnetic Fields. American Journal Of Epidemiology 1998, 148: 467-474. PMID: 9737559, DOI: 10.1093/oxfordjournals.aje.a009672.Peer-Reviewed Original Research
1996
Asthma among Puerto Rican Hispanics: a multi-ethnic comparison study of risk factors.
Beckett W, Belanger K, Gent J, Holford T, Leaderer B. Asthma among Puerto Rican Hispanics: a multi-ethnic comparison study of risk factors. American Journal Of Respiratory And Critical Care Medicine 1996, 154: 894-899. PMID: 8887582, DOI: 10.1164/ajrccm.154.4.8887582.Peer-Reviewed Original ResearchConceptsRisk factorsPuerto Rican HispanicsSocioeconomic statusHispanic ethnicityHispanic mothersEnvironmental tobacco smoke exposureIndependent risk factorPhysician-diagnosed asthmaPrevalence of asthmaTobacco smoke exposureStrong risk factorAfrican American ethnicityEnvironmental risk factorsYr of ageLow socioeconomic statusStudy of asthmaNon-Hispanic whitesMo of ageActive smokingAsthmatic childrenSmoke exposureChildhood asthmaCigarette smokersMaternal ageMaternal historyMaternal Caffeine Consumption and Spontaneous Abortion: A Prospective Cohort Study
Dlugosz L, Belanger K, Hellenbrand K, Holford T, Leaderer B, Bracken M. Maternal Caffeine Consumption and Spontaneous Abortion: A Prospective Cohort Study. Epidemiology 1996, 7: 250-255. PMID: 8728437, DOI: 10.1097/00001648-199605000-00008.Peer-Reviewed Original ResearchConceptsSpontaneous abortionCaffeine consumptionYale-New Haven HospitalMaternal caffeine consumptionProspective cohort studyCohort studyEarly pregnancyPregnant womenOdds ratioSoda drinkingElevated riskCaffeine beveragesBeverage consumptionCaffeine beverage consumptionCigarette useFirst monthPregnancySixteenth weekObserved associationsAbortionCup of teaCaffeineTeaGestationHospital
1995
Measurement of Exposure to Environmental Tobacco Smoke in Pregnant Women
O'Connor T, Holford T, Leaderer B, Hammond S, Bracken M. Measurement of Exposure to Environmental Tobacco Smoke in Pregnant Women. American Journal Of Epidemiology 1995, 142: 1315-1321. PMID: 7503052, DOI: 10.1093/oxfordjournals.aje.a117599.Peer-Reviewed Original ResearchConceptsUrine cotinineEnvironmental tobacco smokePregnant womenTobacco smokeWork exposureAir nicotine concentrationsSelf-reported exposurePersonal air monitorsExposure assessment methodsAir nicotineMeasurement of exposureHome exposureCotinineNicotine concentrationsExposure classificationWomenCohen's kappaExposureSpearman rank-order correlation coefficientAir monitorsRank-order correlation coefficientKappaSocial exposureSmokeHigh levelsEXPOSURE TO ELECTROMAGNETIC FIELDS DURING PREGNANCY WITH EMPHASIS ON ELECTRICALLY HEATED BEDS
Bracken M, Belanger K, Hellenbrand K, Dlugosz L, Holford T, McSharry J, Addesso K, Leaderer B. EXPOSURE TO ELECTROMAGNETIC FIELDS DURING PREGNANCY WITH EMPHASIS ON ELECTRICALLY HEATED BEDS. Epidemiology 1995, 6: 263-270. PMID: 7619934, DOI: 10.1097/00001648-199505000-00013.Peer-Reviewed Original ResearchConceptsFetal growth retardationGrowth retardationBed useIntrauterine growth retardationVideo display terminal useDose-response relationPersonal monitorsEMF exposureTime-weighted analysisMonitoring of exposureThird trimesterProspective studyFetal growthWire codesHome measurementsReproductive outcomesHuman studiesPregnancyStudy designVideo display terminalsExposure measuresHours of useMeaningful increaseRiskExposure
1986
ASSESSMENT OF EXPOSURE TO INDOOR AIR CONTAMINANTS FROM COMBUSTION SOURCES: METHODOLOGY AND APPLICATION
LEADERER B, ZAGRANISKI R, BERWICK M, STOLWIJK J. ASSESSMENT OF EXPOSURE TO INDOOR AIR CONTAMINANTS FROM COMBUSTION SOURCES: METHODOLOGY AND APPLICATION. American Journal Of Epidemiology 1986, 124: 275-289. PMID: 3088984, DOI: 10.1093/oxfordjournals.aje.a114386.Peer-Reviewed Original ResearchConceptsAcute respiratory illnessIndoor air pollutant exposuresPersonal NO2 exposuresAir pollutant exposureIndoor NO2 levelsUnvented kerosene space heatersTobacco smokersIndoor air contaminant levelsRespiratory illnessAssessment of exposureIndoor NO2Health effectsEnvironmental exposuresLevels of NO2Unvented combustionNO2 exposureExposure assessmentNational health standardsGas cooking stovesKerosene space heatersPollutant exposureNO2 levelsKerosene heatersExcellent predictorExposure
1979
Ambient sulfates, photochemical oxidants, and acute adverse health effects: An epidemiological study
Zagraniski R, Leaderer B, Stolwijk J. Ambient sulfates, photochemical oxidants, and acute adverse health effects: An epidemiological study. Environmental Research 1979, 19: 306-320. PMID: 315309, DOI: 10.1016/0013-9351(79)90058-6.Peer-Reviewed Original ResearchConceptsAcute adverse health effectsAdverse health effectsHealth effectsTelephone company employeesAsthma clinicChronic bronchitisGroups of subjectsHeavy smokersAcute symptomsSymptom ratesHay feverThroat irritationEpidemiological studiesMore symptomsSuch illnessesEye irritationSusceptible peopleConnecticut areaSmokersIllnessSymptomsIrritationOxidant levelsGroupNew Haven