2022
Valeric acid acts as a novel HDAC3 inhibitor against prostate cancer
Han R, Yang H, Li Y, Ling C, Lu L. Valeric acid acts as a novel HDAC3 inhibitor against prostate cancer. Medical Oncology 2022, 39: 213. PMID: 36175803, PMCID: PMC9522682, DOI: 10.1007/s12032-022-01814-9.Peer-Reviewed Original ResearchConceptsProstate cancer cellsProstate cancerHDAC3 inhibitorCancer cellsCancer-related deathAnti-cancer effectsVivo mouse modelAnti-cancer efficacyAnti-cancer activityMouse modelNew agentsSecond causeHDAC inhibitorsCancerNormal cellsInhibitorsValeric acidCellsCASP3 activityCulture systemDiseaseChemosensitizers
2013
Intestinal microbiome and digoxin inactivation: meal plan for digoxin users?
Lu L, Wu Y, Zuo L, Luo X, Large PJ. Intestinal microbiome and digoxin inactivation: meal plan for digoxin users? World Journal Of Microbiology And Biotechnology 2013, 30: 791-799. PMID: 24105082, DOI: 10.1007/s11274-013-1507-x.Peer-Reviewed Original ResearchConceptsDigoxin inactivationIntestinal microbiomeDigoxin usersArginine supplementsInactivation of digoxinBioavailability of digoxinHeart diseaseEpidemiological dataAnimal modelsMeal planTherapeutic agentsMetabolism of argininePotential interventionsDigoxinDiseaseDigoxin activityHuman diseasesRecent studiesMicrobiomeSupplementsBioavailabilityInactivationAgents