2024
Prediagnostic Plasma Nutrimetabolomics and Prostate Cancer Risk: A Nested Case–Control Analysis Within the EPIC Study
Almanza-Aguilera E, Martínez-Huélamo M, López-Hernández Y, Guiñón-Fort D, Guadall A, Cruz M, Perez-Cornago A, Rostgaard-Hansen A, Tjønneland A, Dahm C, Katzke V, Schulze M, Masala G, Agnoli C, Tumino R, Ricceri F, Lasheras C, Crous-Bou M, Sánchez M, Aizpurua-Atxega A, Guevara M, Tsilidis K, Chatziioannou A, Weiderpass E, Travis R, Wishart D, Andrés-Lacueva C, Zamora-Ros R. Prediagnostic Plasma Nutrimetabolomics and Prostate Cancer Risk: A Nested Case–Control Analysis Within the EPIC Study. Cancers 2024, 16: 4116. PMID: 39682302, PMCID: PMC11639937, DOI: 10.3390/cancers16234116.Peer-Reviewed Original ResearchProstate cancer riskProstate cancerPCa riskBiomarkers of food intakeMultivariate conditional logistic regression analysisNested case-control analysisAdvanced PCa riskFatal prostate cancerCancer and NutritionConditional logistic regression analysisOverall PCa riskEuropean Prospective InvestigationMetabolite concentrationsCase-control analysisCase-control pairsLogistic regression analysisClinically relevant tumor subtypesMetabolomics approachTumor subtypesProspective InvestigationClinical subtypesCancer riskFood intakeMetabolic alterationsEPIC study
2023
Prediagnostic selenium status, selenoprotein gene variants and association with breast cancer risk in a European cohort study
Hughes D, Schomburg L, Jenab M, Biessy C, Méplan C, Moskal A, Sun Q, Demircan K, Fedirko V, Weiderpass E, Mukhtar M, Olsen A, Tjønneland A, Overvad K, Schulze M, Nøst T, Skeie G, Olsen K, Ricceri F, Grioni S, Palli D, Masala G, Tumino R, Pasanisi F, Amiano P, Colorado Yohar S, Agudo A, Sánchez M, Ardanaz E, Sund M, Andersson A, Perez-Cornago A, Travis R, Heath A, Dossus L. Prediagnostic selenium status, selenoprotein gene variants and association with breast cancer risk in a European cohort study. Free Radical Biology And Medicine 2023, 209: 381-393. PMID: 37923090, DOI: 10.1016/j.freeradbiomed.2023.10.401.Peer-Reviewed Original ResearchConceptsAssociated with BC riskBC riskCase-control pairsOdds ratioMultivariable-adjusted logistic regression modelsBreast cancer riskInfluence BC riskCancer and NutritionConfidence intervalsEuropean Prospective InvestigationHigher risk of BCPremenopausal BC riskRisk of BCPrevent breast cancerAssociated with lower riskEuropean cohort studiesBreast cancerGenetic variant associationsLogistic regression modelsGlutathione peroxidase 3Multiple testing correctionStatistically significant associationPremenopausal BCCancer riskVariant associations