Lingzhi Chu
Postdoctoral AssociateAbout
Research
Publications
2025
Mortality risk and burden associated with non-optimum temperatures in Puerto Rico
Díaz-Collado F, Chu L, Carrión D, Méndez-Lázaro P, Chen K. Mortality risk and burden associated with non-optimum temperatures in Puerto Rico. Environmental Research Letters 2025, 20: 104032. PMID: 40932903, PMCID: PMC12419553, DOI: 10.1088/1748-9326/ae013e.Peer-Reviewed Original ResearchNon-optimum temperaturesMortality riskConditional quasi-Poisson regressionRisk of all-cause mortalityDaily mortality countsHealth impactsRobust epidemiological evidenceQuasi-Poisson regressionTime-series studyAll-Cause MortalityTemperature-related deathsTime riskMortality fractionsMinimum mortality temperatureMortality burdenPuerto RicoRelative riskEpidemiological evidenceMortality countsMortality temperatureDeath rateSmall Island Developing StatesCaribbean Small Island Developing StatesVulnerable municipalitiesHeat-related death ratesRacial and ethnic disparities in exposure to short-term NO2 air pollution in California during 1980–2022
Liu R, Chu L, Rogne T, Ma X, Chen K. Racial and ethnic disparities in exposure to short-term NO2 air pollution in California during 1980–2022. Journal Of Hazardous Materials 2025, 496: 139309. PMID: 40695125, DOI: 10.1016/j.jhazmat.2025.139309.Peer-Reviewed Original ResearchConceptsShort-term NO2 exposure anChemical transport model outputExposure to ambient nitrogen dioxideNO2 air pollutionAmbient nitrogen dioxideTransport model outputAir pollutionNitrogen dioxideSpatiotemporal variationsIsland groupsCoefficient of determinationStudy periodModel outputAlaskaConcentrationGeospatial dataExposureCaliforniaEnvironmental justice literaturePollutionJoint Exposure to Ozone and Temperature and Acute Myocardial Infarction Among Adults Aged 18 to 64 Years in the United States
Chu L, Wang R, Gross C, Wei J, Lu Y, Krumholz H, Ma X, Chen K. Joint Exposure to Ozone and Temperature and Acute Myocardial Infarction Among Adults Aged 18 to 64 Years in the United States. Circulation 2025, 152: 246-256. PMID: 40458867, PMCID: PMC12303734, DOI: 10.1161/circulationaha.124.073614.Peer-Reviewed Original ResearchIncident acute myocardial infarctionAcute myocardial infarctionIncreased oddsRisk of acute myocardial infarctionHigher risk of acute myocardial infarctionProbability of acute myocardial infarctionOccurrence of acute myocardial infarctionRandom-effects meta-analysisCase-crossover studyMultivariate random-effects meta-analysisExposure to ozoneRegion-specific estimatesMyocardial infarctionStatistical interaction termsAmbient ozone pollutionPrevention strategiesUnited StatesJoint exposureMeta-analysisAdult ageYoung adultsHigh riskAdultsOddsInteraction termsFloods and cause-specific mortality in the United States applying a triply robust approach
Chu L, Warren J, Spatz E, Lowe S, Lu Y, Ma X, Ross J, Krumholz H, Chen K. Floods and cause-specific mortality in the United States applying a triply robust approach. Nature Communications 2025, 16: 2853. PMID: 40122917, PMCID: PMC11930965, DOI: 10.1038/s41467-025-58236-0.Peer-Reviewed Original ResearchConceptsCDC's National Center for Health StatisticsNational Center for Health StatisticsCause-specific mortality ratesCenter for Health StatisticsCause-specific mortalityHealth impacts of floodingExcess all-cause deathsLong-term health risksFlood daysLong-term associationDeath recordsHealth StatisticsConfounder adjustmentExternal causesStorm Events DatabaseAll-cause deathHealth impactsImpact of floodsPropensity scorePost‐flood yearMortality rateMyocardial infarctionPost-floodContiguous U.S.Respiratory diseaseShort‐Term Associations Between Ambient Ozone and Acute Myocardial Infarction Onset Among Younger Patients: Results From the VIRGO Study
Zhang S, Chu L, Lu Y, Wei J, Dubrow R, Chaudhry S, Spatz E, Krumholz H, Chen K. Short‐Term Associations Between Ambient Ozone and Acute Myocardial Infarction Onset Among Younger Patients: Results From the VIRGO Study. GeoHealth 2025, 9: e2024gh001234. PMID: 39968338, PMCID: PMC11833228, DOI: 10.1029/2024gh001234.Peer-Reviewed Original ResearchAcute myocardial infarction subtypeShort-term associationsAcute myocardial infarctionAcute myocardial infarction onsetAMI riskEffect modificationAssociated with increased AMI riskParticipant's home addressNon-Hispanic blacksNon-ST-segment elevation acute myocardial infarctionNon-Hispanic whitesCase-crossover designType 1 AMIConditional logistic regressionIncreased AMI riskMyocardial infarction onsetType 2 AMIAcute myocardial infarction patientsST-segment elevation acute myocardial infarctionLifestyle factorsSociodemographic statusHome addressUS hospitalsStratified analysisSpatiotemporal deep learning approach
2024
Ambient Temperature and Stroke Risk Among Adults Aged 18-64 Years A Case-Crossover Study
Chu L, Wang R, Gross C, Chen K, Ma X. Ambient Temperature and Stroke Risk Among Adults Aged 18-64 Years A Case-Crossover Study. Journal Of The American College Of Cardiology 2024, 84: 2327-2331. PMID: 39453364, PMCID: PMC12060033, DOI: 10.1016/j.jacc.2024.08.058.Peer-Reviewed Original ResearchFloods and cause-specific mortality in the United States during 2001-2020
Chu L, Warren J, Spatz E, Lowe S, Lu Y, Ma X, Ross J, Krumholz H, Chen K. Floods and cause-specific mortality in the United States during 2001-2020. ISEE Conference Abstracts 2024, 2024 DOI: 10.1289/isee.2024.1705.Peer-Reviewed Original ResearchShort-term association between ambient ozone and onset of acute myocardial infarction of young patients: Results from the VIRGO study
Zhang S, Chu L, Lu Y, Krumholz H, Chen K. Short-term association between ambient ozone and onset of acute myocardial infarction of young patients: Results from the VIRGO study. ISEE Conference Abstracts 2024, 2024 DOI: 10.1289/isee.2024.0539.Peer-Reviewed Original ResearchA unified framework for assessing interaction effects among environmental exposures in epidemiologic studies: A case study on temperature, air pollution, and kidney-related conditions in New York state
Chu L, Chen K, Yang Z, Crowley S, Dubrow R. A unified framework for assessing interaction effects among environmental exposures in epidemiologic studies: A case study on temperature, air pollution, and kidney-related conditions in New York state. Environmental Research 2024, 248: 118324. PMID: 38301759, DOI: 10.1016/j.envres.2024.118324.Peer-Reviewed Original ResearchAir pollutionMultiplicative interaction effectsNew York StateEstimated health burdenCase-crossover designEvaluation of effect modificationBi-variate associationsAssess interaction effectsConditional logistic modelMeasures of exposureInteraction effectsEffect modificationPollutionExposure variablesHealth burdenEpidemiological studiesEnvironmental exposuresLog-linear modelLogistic modelInteraction termsQuantitative frameworkAirCase studyExposureAlert system
2023
Besieged on all sides: the future burden of high-temperature-related kidney disease
Chu L, Chen K. Besieged on all sides: the future burden of high-temperature-related kidney disease. The Lancet Regional Health - Western Pacific 2023, 41: 100941. PMID: 37886030, PMCID: PMC10598698, DOI: 10.1016/j.lanwpc.2023.100941.Peer-Reviewed Original Research
News
News
- November 07, 2025
Warming U.S. climate linked to rising deaths from heat
- June 18, 2025Source: Medscape
Moderate Air Pollution and Heat Exposure Raise Heart Attack Risk in Younger Adults, Study Finds
- June 03, 2025Source: Yale News
Insights & Outcomes: Star Music, Kavli Kudos, and Summertime Heart Risks
- November 04, 2024
2024 Lancet Report on Climate Change Reveals Record-breaking Health Threats Associated With Climate Inaction