2023
Dynamics of chikungunya virus transmission in the first year after its introduction in Brazil: A cohort study in an urban community
Anjos R, Portilho M, Jacob-Nascimento L, Carvalho C, Moreira P, Sacramento G, Nery N, de Oliveira D, Cruz J, Cardoso C, Argibay H, Plante K, Plante J, Weaver S, Kitron U, Reis M, Ko A, Costa F, Ribeiro G. Dynamics of chikungunya virus transmission in the first year after its introduction in Brazil: A cohort study in an urban community. PLOS Neglected Tropical Diseases 2023, 17: e0011863. PMID: 38150470, PMCID: PMC10775974, DOI: 10.1371/journal.pntd.0011863.Peer-Reviewed Original Research
2022
Structural factors associated with SARS-CoV-2 infection risk in an urban slum setting in Salvador, Brazil: A cross-sectional survey
Fofana MO, Nery N, Ticona J, de Andrade Belitardo EMM, Victoriano R, Anjos RO, Portilho MM, de Santana MC, dos Santos LL, de Oliveira D, Cruz JS, Muenker MC, Khouri R, Wunder EA, Hitchings MDT, Johnson O, Reis MG, Ribeiro GS, Cummings DAT, Costa F, Ko AI. Structural factors associated with SARS-CoV-2 infection risk in an urban slum setting in Salvador, Brazil: A cross-sectional survey. PLOS Medicine 2022, 19: e1004093. PMID: 36074784, PMCID: PMC9499230, DOI: 10.1371/journal.pmed.1004093.Peer-Reviewed Original ResearchConceptsSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infectionAcute respiratory syndrome coronavirus 2 infectionSARS-CoV-2 infection riskUrban slumsSyndrome coronavirus 2 infectionSARS-CoV-2 seroprevalenceSARS-CoV-2 incidenceCoronavirus 2 infectionCross-sectional serosurveyMain outcome measuresUrban slum populationPresence of IgGSARS-CoV-2 spike proteinUrban slum communityCross-sectional surveyUrban slum residentsCumulative incidenceMedian ageRisk factorsOutcome measuresStudy populationHigh seroprevalenceMedian dailyPandemic waveGender distributionReliable estimation of SARS-CoV-2 anti-spike protein IgG titers from single dilution optical density values in serologic surveys
Belitardo E, Nery N, Ticona J, Portilho MM, Mello IO, Ribeiro GS, Reis MG, Costa F, Cummings DAT, Ko AI, Fofana MO. Reliable estimation of SARS-CoV-2 anti-spike protein IgG titers from single dilution optical density values in serologic surveys. Diagnostic Microbiology And Infectious Disease 2022, 104: 115807. PMID: 36162285, PMCID: PMC9428330, DOI: 10.1016/j.diagmicrobio.2022.115807.Peer-Reviewed Original ResearchMeSH KeywordsAntibodies, ViralCOVID-19HumansImmunoglobulin GReproducibility of ResultsSARS-CoV-2Seroepidemiologic StudiesConceptsSARS-CoV-2 incidenceCommunity-based cohortPopulation-level immunitySARS-CoV-2Large-scale serosurveysELISA optical densityIgG titersIgG ELISAPandemic evolvesSerologic surveyTitersOptical density valuesPopulation-level changesSerosurveyImmunitySingle dilutionSerial dilutionsNODCohortIncidenceELISASerum
2019
Performance of recombinant chimeric proteins in the serological diagnosis of Trypanosoma cruzi infection in dogs
Leony L, Freitas N, Del-Rei R, Carneiro C, Reis A, Jansen A, Xavier S, Gomes Y, Silva E, Reis M, Fraga D, Celedon P, Zanchin N, Dantas-Torres F, Santos F. Performance of recombinant chimeric proteins in the serological diagnosis of Trypanosoma cruzi infection in dogs. PLOS Neglected Tropical Diseases 2019, 13: e0007545. PMID: 31242195, PMCID: PMC6615644, DOI: 10.1371/journal.pntd.0007545.Peer-Reviewed Original ResearchConceptsCruzi infectionIBMP-8.4Cruzi IgG antibodiesDiagnostic performanceTrypanosoma cruzi infectionAntigenic matrixIgG antibody detectionIBMP-8.3IBMP-8.1IBMP-8.2High diagnostic performanceSuperior diagnostic performanceIgG antibodiesChimeric antigenInfected dogsVisceral leishmaniasisEpidemiological studiesRecombinant chimeric proteinAntibody detectionInfectious diseasesTransmission riskSerological diagnosisDogsROC curveDiagnostic potentialAccuracy of the SD BIOLINE Dengue Duo for rapid point-of-care diagnosis of dengue
Kikuti M, Cruz J, Rodrigues M, Tavares A, Paploski I, Silva M, Santana P, Tauro L, Silva G, Campos G, Araújo J, Kitron U, Reis M, Ribeiro G. Accuracy of the SD BIOLINE Dengue Duo for rapid point-of-care diagnosis of dengue. PLOS ONE 2019, 14: e0213301. PMID: 30840708, PMCID: PMC6402663, DOI: 10.1371/journal.pone.0213301.Peer-Reviewed Original ResearchConceptsRapid diagnosis testsNon-dengue febrile patientsFebrile patientsHealthy controlsBlood donorsLaboratory-confirmed dengue casesSD BIOLINE Dengue DuoSecondary DENV infectionDengue virus antigenAcute-phase seraDengue diagnostic testsRepresentative serum samplesDengue-endemic regionsDengue-endemic areasSample of casesDENV antibodiesDENV infectionNS1 ELISAPrimary infectionDengue diagnosisMedical treatment decisionsTreatment decisionsVirus antigenRDT accuracyRDT sensitivity
2014
HBV/HDV co‐infection in the Western Brazilian Amazonia: an intriguing mutation among HDV genotype 3 carriers
Kay A, da Silva E, Pedreira H, Negreiros S, Lobato C, Braga W, Muwonge R, Dény P, Reis M, Zoulim F, Trepo C, D'Oliveira A, Salcedo J, Schinoni M, Parana R. HBV/HDV co‐infection in the Western Brazilian Amazonia: an intriguing mutation among HDV genotype 3 carriers. Journal Of Viral Hepatitis 2014, 21: 921-924. PMID: 25040045, DOI: 10.1111/jvh.12267.Peer-Reviewed Original Research
2005
HEV, TTV and GBV-C/HGV markers in patients with acute viral hepatitis
Lyra A, Pinho J, Silva L, Sousa L, Saraceni C, Braga E, Pereira J, Zarife M, Reis M, Lyra L, da Silva L, Carrilho F. HEV, TTV and GBV-C/HGV markers in patients with acute viral hepatitis. Brazilian Journal Of Medical And Biological Research 2005, 38: 767-775. PMID: 15917959, DOI: 10.1590/s0100-879x2005000500015.Peer-Reviewed Original ResearchConceptsAnti-HEV IgMHepatitis AGenotype 1C hepatitisAcute hepatitisAcute viral hepatitis AAnti-HEV IgG antibodiesAcute hepatitis A casesPrevalence of HEVAcute hepatitis AAcute viral hepatitisHepatitis A casesViral hepatitis ATTV genotype 1HEV IgGHGV infectionHGV markersAminotransferase levelsHepatitis EViral hepatitisIgG antibodiesBlood donorsHepatitisHGV isolatesPatients
2001
Evaluation of Recombinant Leptospira Antigen-Based Enzyme-Linked Immunosorbent Assays for the Serodiagnosis of Leptospirosis
Flannery B, Costa D, Carvalho F, Guerreiro H, Matsunaga J, Da Silva E, Ferreira A, Riley L, Reis M, Haake D, Ko A. Evaluation of Recombinant Leptospira Antigen-Based Enzyme-Linked Immunosorbent Assays for the Serodiagnosis of Leptospirosis. Journal Of Clinical Microbiology 2001, 39: 3303-3310. PMID: 11526167, PMCID: PMC88335, DOI: 10.1128/jcm.39.9.3303-3310.2001.Peer-Reviewed Original ResearchConceptsEnzyme-linked immunosorbent assayIgG enzyme-linked immunosorbent assaySerodiagnosis of leptospirosisHealthy individualsImmunosorbent assayTest-positive individualsCases of leptospirosisHigh-incidence regionsLyme disease patientsMicroscopic agglutination testConvalescent phaseHepatitis patientsAcute phaseDengue patientsDisease patientsPatient seraHealthy residentsLeptospira antigensCutoff valueDiagnostic utilityPatientsAgglutination testUseful antigenLeptospirosisAntigen