Biomarkers of Hemolysis and Inflammation in Sickle Cell Disease Children: Association with Nasopharynx and Oropharynx Bacteria colonization
Rocha L, Seixas M, Cerqueira B, Lopes V, Reis M, Goncalves M. Biomarkers of Hemolysis and Inflammation in Sickle Cell Disease Children: Association with Nasopharynx and Oropharynx Bacteria colonization. Blood 2011, 118: 2140. DOI: 10.1182/blood.v118.21.2140.2140.Peer-Reviewed Original ResearchHigh ferritin serum levelsFerritin serum levelsSCD patientsSerum levelsS. pneumoniaeNasopharyngeal colonizationNasopharynx colonizationHbSS genotypeSickle cell disease childrenS. aureusBacteria colonizationBiomarkers of hemolysisHigher leukocyte numbersPneumococcal penicillin resistanceHigher neutrophil countS. pneumoniae colonizationCause of infectionCross-sectional studyOccurrence of infectionMultivariate analysis modelNeutrophil countSCD childrenHigh ferritinPneumonia occurrencePneumoniae colonization