Yuan Lu, ScD
Assistant Professor of Medicine (Cardiology) and of Biomedical Informatics and Data Science and of Epidemiology (Chronic Diseases)Cards
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Assistant Professor of Medicine (Cardiology) and of Biomedical Informatics and Data Science and of Epidemiology (Chronic Diseases)
Biography
Dr. Lu was trained in epidemiology and global health, with a particular focus on cardiovascular diseases. She obtained both of her ScD and MSc Degrees in Global Health and Population at the Harvard School of Public Health. She works in the intersection of cardiovascular disease prevention, clinical informatics, and digital health, using implementation science methods to resolve real-world issues. Her long-term goal is to improve care and outcomes of cardiovascular diseases by designing and implementing technology-based interventions.
She successfully completed an NHLBI K12 career development award in implementation science. During this award, she harnessed electronic health records from the Yale New Haven Health System to identify patients with persistent hypertension and designing decision support systems to improve their care. Currently, Dr. Lu serves as the Principal Investigator for an NIH R01 grant, where she leverages real-world data from five electronic health record databases encompassing over 100 million US adults. The goal of this endeavor is to generate real-world evidence that informs decisions regarding hypertension treatment escalation.
In addition to her domestic contributions, Dr. Lu has engaged in groundbreaking collaborative projects between Yale University and the Chinese National Center for Cardiovascular Diseases in Beijing. These include the Millions Persons Project that assembles remarkable population health and biomedical resources from 5 million individuals across China. Moreover, she has collaborated with the NCD Risk Factor Collaboration (NCD-RisC) on global analyses examining the impact of risk factors on the worldwide burden of cardiovascular diseases.
She has authored over 150 peer-reviewed publications, including first author articles in leading journals such as The Lancet, JAMA, BMJ, Circulation, and JACC, and her work has been cited more than 50,000 times. Dr. Lu is the recipient of the 2022 John H. Laragh Research Award of the American Journal of Hypertension for her contribution to the field of hypertension. She is a Fellow of the American Heart Association and the American College of Cardiology, and currently serves as an Executive Associate Editor at JACC.
Appointments
Cardiovascular Medicine
Assistant ProfessorPrimaryBiomedical Informatics & Data Science
Assistant ProfessorSecondaryChronic Disease Epidemiology
Assistant ProfessorSecondary
Other Departments & Organizations
- All Institutions
- Biomedical Informatics & Data Science
- Cardiovascular Medicine
- Center for Outcomes Research & Evaluation (CORE)
- Chronic Disease Epidemiology
- Internal Medicine
- Janeway Society
- Preventive Cardiovascular Health Program at Yale
- Yale Obesity Research Center (Y-Weight)
- Yale UNRAVEL Study
Education & Training
- ScD
- Harvard School of Public Health, Global Health and Population (2015)
Research
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Overview
Medical Research Interests
Public Health Interests
ORCID
0000-0001-5264-2169- View Lab Website
Yale/YNHH Center for Outcomes Research and Evaluation (CORE)
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
Harlan Krumholz, MD, SM
Erica Spatz, MD, MHS
Cesar Caraballo-Cordovez, MD
Mitsuaki Sawano, MD, PhD
Rohan Khera, MD, MS
Jeph Herrin, PhD
Cardiovascular Diseases
Chronic Disease
Publications
2026
Primary Prevention Antihypertensive Eligibility With the 2025 AHA/ACC Guideline
Malik D, Essa M, Lu Y, Yang H, Spatz E, Krumholz H, Faridi K. Primary Prevention Antihypertensive Eligibility With the 2025 AHA/ACC Guideline. Hypertension 2026, 83: e26387. PMID: 41849572, DOI: 10.1161/hypertensionaha.125.26387.Peer-Reviewed Original ResearchAltmetricOcular Symptoms in Long COVID: A Cross-Sectional Study
Kaleem S, Sawano M, Arun A, Warner F, Zhou T, Huang C, Bhattacharjee B, Lu Y, Iwasaki A, Nwanyanwu K, Ahmed I, Krumholz H. Ocular Symptoms in Long COVID: A Cross-Sectional Study. Clinical Ophthalmology 2026, Volume 20 DOI: 10.2147/OPTH.S565596.Peer-Reviewed Original ResearchOcular Symptoms in Long COVID: A Cross-Sectional Study
Kaleem S, Sawano M, Arun A, Warner F, Zhou T, Huang C, Bhattacharjee B, Lu Y, Iwasaki A, Nwanyanwu K, Ahmed I, Krumholz H. Ocular Symptoms in Long COVID: A Cross-Sectional Study. Clinical Ophthalmology 2026, 20: 565596. PMID: 41907807, PMCID: PMC13024366, DOI: 10.2147/opth.s565596.Peer-Reviewed Original ResearchAltmetricConceptsOcular symptomsHealth conditionsPre-pandemic health conditionsPoor health statusInterquartile rangeCross-sectional studyCross-sectional analysisBonferroni-adjusted p-valueHealth profileHealth scoresLoss of visionHealth statusHigher RatesHousing stabilitySocioeconomic characteristicsMyalgic encephalomyelitis/chronic fatigue syndromeDry eyeFinancial difficultiesFatigue syndromeCategorical variablesCOVID-19 infectionSocioeconomic challengesCOVID symptomsSevere phenotypeParticipantsGLP-1 Receptor Agonist Prescriptions for Adolescents With Obesity and Associated Disparities
Kim C, Sharifi M, Ross J, Chen Y, Xu H, Krumholz H, Lu Y. GLP-1 Receptor Agonist Prescriptions for Adolescents With Obesity and Associated Disparities. JAMA Pediatrics 2026, 180: 334-336. PMID: 41557442, PMCID: PMC12820773, DOI: 10.1001/jamapediatrics.2025.5708.Peer-Reviewed Original ResearchAltmetricSleep Duration by Atherosclerotic Cardiovascular Disease Status A JACC Data Report on Trends in the United States, 2020-2024
Arun A, Shah R, Lu Y, Dhruva S, Krumholz H. Sleep Duration by Atherosclerotic Cardiovascular Disease Status A JACC Data Report on Trends in the United States, 2020-2024. Journal Of The American College Of Cardiology 2026, 87: 1153-1156. PMID: 41811010, DOI: 10.1016/j.jacc.2025.12.043.Peer-Reviewed Original ResearchCitationsAltmetricHealth Care Affordability by Atherosclerotic Cardiovascular Disease Status A JACC Data Report on Trends in the United States, 2019-2024
Shah R, Arun A, Lu Y, Dhruva S, Wadhera R, Krumholz H. Health Care Affordability by Atherosclerotic Cardiovascular Disease Status A JACC Data Report on Trends in the United States, 2019-2024. Journal Of The American College Of Cardiology 2026, 87: 1145-1148. PMID: 41811008, DOI: 10.1016/j.jacc.2025.12.042.Peer-Reviewed Original ResearchCitationsAltmetricOut-of-Pocket Costs and Financial Burden Among Working-Age Adults With Cardiovascular Conditions A JACC Data Report on Trends in the United States, 2007-2022
Dash S, Zheng Z, Qian Y, Dhruva S, Lu Y, Curtis L, Wadhera R. Out-of-Pocket Costs and Financial Burden Among Working-Age Adults With Cardiovascular Conditions A JACC Data Report on Trends in the United States, 2007-2022. Journal Of The American College Of Cardiology 2026, 87: 1135-1137. PMID: 41811005, DOI: 10.1016/j.jacc.2025.12.039.Peer-Reviewed Original ResearchCitationsAltmetricDietary Quality by Sex, Age, and Race/Ethnicity A JACC Data Report on Trends in the United States, 1999-2020
Yang H, Dhruva S, Wadhera R, Arun A, Shah R, Krumholz H, Lu Y. Dietary Quality by Sex, Age, and Race/Ethnicity A JACC Data Report on Trends in the United States, 1999-2020. Journal Of The American College Of Cardiology 2026, 87: 1161-1164. PMID: 41811012, DOI: 10.1016/j.jacc.2025.12.051.Peer-Reviewed Original ResearchCitationsAltmetricConceptsHealth Care Access by Atherosclerotic Cardiovascular Disease Status A JACC Data Report on Trends in the United States, 2019-2024
Arun A, Shah R, Lu Y, Dhruva S, Wadhera R, Krumholz H. Health Care Access by Atherosclerotic Cardiovascular Disease Status A JACC Data Report on Trends in the United States, 2019-2024. Journal Of The American College Of Cardiology 2026, 87: 1141-1144. PMID: 41811007, DOI: 10.1016/j.jacc.2025.12.045.Peer-Reviewed Original ResearchCitationsAltmetricHealth Care Utilization by Atherosclerotic Cardiovascular Disease Status A JACC Data Report on Trends in the United States, 2019-2024
Arun A, Shah R, Lu Y, Dhruva S, Krumholz H. Health Care Utilization by Atherosclerotic Cardiovascular Disease Status A JACC Data Report on Trends in the United States, 2019-2024. Journal Of The American College Of Cardiology 2026, 87: 1157-1160. PMID: 41811011, DOI: 10.1016/j.jacc.2025.12.050.Peer-Reviewed Original ResearchCitationsAltmetric
Academic Achievements & Community Involvement
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Activities
activity National Institutes of Health (NIH)
06/01/2023 - PresentPeer Review Groups and Grant Study SectionsRevieweractivity JACC
02/01/2024 - PresentJournal ServiceAssociate Editoractivity American Heart Association
07/01/2021 - PresentProfessional OrganizationsFellowactivity JACC
07/01/2024 - PresentJournal ServiceAssociate Editoractivity American College of Cardiology
03/01/2025 - PresentProfessional OrganizationsFellow
Honors
honor Fellow
03/01/2025National AwardAmerican College of CardiologyDetailsUnited Stateshonor Office of Health Equity Research Award for Yale Research Excellence, Finalist
02/23/2024Yale School of Medicine AwardOffice of Health Equity Research, Yale School of MedicineDetailsUnited Stateshonor Office of Health Equity Research Award for Yale Research Excellence
02/01/2023Yale University AwardOffice of Health Equity Research, Yale School of MedicineDetailsUnited Stateshonor The John Laragh Research Award
07/29/2022National AwardAmerican Journal of HypertensionDetailsUnited Stateshonor Batten Fellowship Award
07/01/2022Regional AwardSentara FoundationDetailsUnited States
Teaching & Mentoring
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Mentoring
Chungsoo Kim
Postdoc2024 - PresentIvan Wu
Postgrad associate2024 - PresentAdith Arun
Medical student2024 - PresentXin Xin
Graduate student2023 - 2024
News
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News
- February 26, 2026Source: Healio - Cardiology Today (with Yuan Lu)
Traditional Chinese mind-body practice improves blood pressure
- July 14, 2025Source: Cardiologytoday
Delays in Hypertension Diagnosis May Hold Up Treatment, Increase CVD Risk
- June 03, 2025Source: Yale News
Insights & Outcomes: Star Music, Kavli Kudos, and Summertime Heart Risks
- May 05, 2025
Why Aren’t People Who Need Weight Loss Drugs Getting Them?
Get In Touch
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Contacts
Locations
Yale Center for Outcomes Research and Evaluation
Academic Office
195 Church Street, Fl 5th
New Haven, CT 06510
Events
Everyone Lavanya Bellumkonda, MD - Andrew Y. Chang, MD, PhD - Kai Chen, PhD - Yuan Lu, ScD - Jodi Sherman, MD - Erica Spatz, MD, MHSZoom link will be shared after registration.