2021
The Historic Elimination of Mother-to-Child HIV and Syphilis Transmission in Puerto Rico.
Vermund SH, Febo I. The Historic Elimination of Mother-to-Child HIV and Syphilis Transmission in Puerto Rico. Puerto Rico Health Sciences Journal 2021, 40: 3-5. PMID: 33876911, PMCID: PMC8363137.Peer-Reviewed Original ResearchConceptsHigh background prevalenceElimination of HIVWorld Health OrganizationChildren HIVInfection overallPerinatal transmissionAntenatal servicesBackground prevalenceHIV riskSyphilis transmissionSyphilis therapyHIVHealth OrganizationSyphilisMothersPuerto RicoInfantsTherapyPrevalenceCareEliminationWomen
2004
Prevention of mother-to-child transmission of HIV in Africa.
Vermund SH. Prevention of mother-to-child transmission of HIV in Africa. Topics In Antiviral Medicine 2004, 12: 130-4. PMID: 15647608.Peer-Reviewed Original ResearchConceptsChild transmissionHIV infectionInternational AIDS Society-USA courseMaternal plasma viral loadExclusive formula feedingNevirapine resistance mutationsSingle-dose nevirapinePrevention of motherPlasma viral loadPerinatal transmission ratePerinatal transmissionAntiretroviral therapyExclusive breastfeedingFormula feedingViral loadMaternal mortalityRisk factorsMortality rateHIVAfrican childrenMixed feedingGreater riskResistance mutationsEarly weaningBreastfeeding
2003
Timing of the maternal drug dose and risk of perinatal HIV transmission in the setting of intrapartum and neonatal single-dose nevirapine
Stringer J, Sinkala M, Chapman V, Acosta EP, Aldrovandi GM, Mudenda V, Stout JP, Goldenberg RL, Kumwenda R, Vermund SH. Timing of the maternal drug dose and risk of perinatal HIV transmission in the setting of intrapartum and neonatal single-dose nevirapine. AIDS 2003, 17: 1659-1665. PMID: 12853748, PMCID: PMC2745973, DOI: 10.1097/00002030-200307250-00010.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBreast FeedingDrug Administration ScheduleFemaleHIV InfectionsHIV SeropositivityHumansInfant, NewbornInfectious Disease Transmission, VerticalLabor, ObstetricNevirapineObstetric Labor ComplicationsPregnancyPregnancy Complications, InfectiousProspective StudiesReverse Transcriptase InhibitorsRisk FactorsTime FactorsConceptsPerinatal HIV transmissionHIV transmissionInfant HIV infection statusNeonatal single-dose nevirapineMaternal drug doseSingle-dose nevirapineHIV infection statusProspective cohort studyPerinatal transmission rateOnset of laborMain outcome measuresMean drug concentrationWeeks of lifeRisk of transmissionNVP levelsNVP prophylaxisNVP syrupObstetrical clinicPerinatal transmissionCohort studyOral doseViral loadPregnant womenPolymerase chain reactionRisk factors
2001
Zambian women's attitudes toward mass nevirapine therapy to prevent perinatal transmission of HIV
Sinkala M, Stout J, Vermund S, Goldenberg R, Stringer J. Zambian women's attitudes toward mass nevirapine therapy to prevent perinatal transmission of HIV. The Lancet 2001, 358: 1611-1612. PMID: 11716891, DOI: 10.1016/s0140-6736(01)06662-4.Peer-Reviewed Original Research
1998
Choriodecidual inflammation: a potentially preventable cause of perinatal HIV-1 transmission?
Goldenberg R, Vermund S, Goepfert A, Andrews W. Choriodecidual inflammation: a potentially preventable cause of perinatal HIV-1 transmission? The Lancet 1998, 352: 1927-1930. PMID: 9863804, DOI: 10.1016/s0140-6736(98)04453-5.Peer-Reviewed Original ResearchConceptsHIV-1Perinatal transmissionProlonged rupturePreterm birthAmniotic cavityPerinatal HIV-1 transmissionAmniotic fluid cytokinesCases of pretermIntrauterine bacterial infectionHIV-1 transmissionObstetric risk factorsAcute chorioamnionitisChronic chorioamnionitisMaternal leucocytesPreventable causeSpontaneous ruptureAntibiotic treatmentRisk factorsChorioamnionitisBacterial infectionsChorioamniotic membranesCytokinesLeucocytesRuptureBirth
1992
Human immunodeficiency virus/acquired immunodeficiency syndrome in pregnant women
Vermund S, Galbraith M, Ebner S, Sheon A, Kaslow R. Human immunodeficiency virus/acquired immunodeficiency syndrome in pregnant women. Annals Of Epidemiology 1992, 2: 773-802. PMID: 1342332, DOI: 10.1016/1047-2797(92)90072-x.Peer-Reviewed Original ResearchConceptsPregnant womenClinical outcomesHuman immunodeficiency virus/Anti-Pneumocystis drugsCells/mm3Adverse clinical outcomesHigh-risk womenHuman immunodeficiency virusLarge multicenter studyImmunodeficiency syndrome (AIDS) epidemicAdequate clinical treatmentHealth care servicesClinical decision makingPerinatal transmissionSelective immunosuppressionHIV diseaseImmunosuppressed womenAvailable antiviralsHIV infectionImmunodeficiency syndromeImmunodeficiency virusMulticenter studyVirus/Therapeutic decisionsHigh risk