Fangyong Li, MS, MPH
Statistician 3Cards
About
Research
Publications
2025
Tracing the evolution of single-cell 3D genomes in Kras-driven cancers
Liu M, Jin S, Agabiti S, Jensen T, Yang T, Radda J, Ruiz C, Baldissera G, Rajaei M, Li F, Townsend J, Muzumdar M, Wang S. Tracing the evolution of single-cell 3D genomes in Kras-driven cancers. Nature Genetics 2025, 1-13. PMID: 40825871, DOI: 10.1038/s41588-025-02297-w.Peer-Reviewed Original ResearchCell-to-cell heterogeneityGenome-wide chromatinGenome compactionGenome architectureGenomic structureGenome mappingGenome regulationLung adenocarcinomaDependent genesKRAS-driven cancersGenomeMouse lung adenocarcinomaCancer progressionEarly tumor progressionSingle cellsCancer stateGenesPancreatic ductal adenocarcinomaInvasive tumorsTherapeutic biomarkersDuctal adenocarcinomaTumor progressionCompartmental changesChromatinCancerThe potential of AI for scale development: A self-report psychosis symptoms measure using ChatGPT
Tayfur S, Hazan H, Li F, Song Z, Corbera S, Tek C, Srihari V. The potential of AI for scale development: A self-report psychosis symptoms measure using ChatGPT. Schizophrenia Research 2025, 284: 111-113. PMID: 40763549, DOI: 10.1016/j.schres.2025.07.030.Peer-Reviewed Original ResearchEnhancing Coordinated Specialty Care Through Early Detection: Impact of Reduced Duration of Untreated Psychosis
Hazan H, Ferrara M, Zhou B, Li F, Imetovski S, Sykes L, Pollard J, Cahill J, Gibbs-Dean T, Corbera S, Karmani S, Riley S, Tayfur S, Tek C, Keshavan M, Srihari V. Enhancing Coordinated Specialty Care Through Early Detection: Impact of Reduced Duration of Untreated Psychosis. Schizophrenia Bulletin 2025, 51: 1730-1737. PMID: 40339151, PMCID: PMC12597490, DOI: 10.1093/schbul/sbaf044.Peer-Reviewed Original ResearchDuration of untreated psychosisFirst-episode psychosisCoordinated Specialty CareUntreated psychosisMediation analysisShorter duration of untreated psychosisFirst-episode psychosis patientsEarly interventionEarly psychosisBenefits of early interventionPsychosisGAFFunctional outcomesGlobal assessmentEarly detection campaignsSpecialty careIntake processRecovery outcomesSpecial treatmentQuality of lifeStreamlining referralsFunctional recoveryScoresPatientsInterventionInsight and Its Trajectory: Predicting the Risk of Psychiatric Hospitalizations Among First-Episode Psychosis During the First Year of Coordinated Specialty Care
Hazan H, Ferrara M, Gibbs-Dean T, Tayfur S, Corbera S, Karmani S, Song Z, Li F, Vlachos I, Selakovic M, Tek C, Srihari V. Insight and Its Trajectory: Predicting the Risk of Psychiatric Hospitalizations Among First-Episode Psychosis During the First Year of Coordinated Specialty Care. Schizophrenia Bulletin 2025, sbaf019. PMID: 40227145, DOI: 10.1093/schbul/sbaf019.Peer-Reviewed Original ResearchCoordinated Specialty CareFirst-episode psychosisBaseline insightRisk of psychiatric hospitalizationFirst-episodeEarly psychosisInsight groupLength of stayPsychiatric hospitalSpecialty carePsychosisLongitudinal trajectoriesGreater reductionsHospital outcomesHigh-low-highPredicting clinical improvementHospital dataModifiable factorsMonths pre-ParticipantsHospitalization riskClinical improvementRecovery trajectoriesReduce hospitalizationsBaselineThe impact of Duration of Untreated Psychosis on functioning and quality of life over one year of Coordinated Specialty Care (CSC)
Hazan H, Tayfur S, Zhou B, Li F, Gibbs-Dean T, Karmani S, Kline E, Ferrara M, Corbera S, Riley S, Sykes L, Tek C, Keshavan M, Srihari V. The impact of Duration of Untreated Psychosis on functioning and quality of life over one year of Coordinated Specialty Care (CSC). PLOS ONE 2025, 20: e0312740. PMID: 39928579, PMCID: PMC11809850, DOI: 10.1371/journal.pone.0312740.Peer-Reviewed Original ResearchConceptsCoordinated Specialty CareQuality of lifeDuration of untreated psychosisDUP groupWorld Health OrganizationYear of coordinated specialty careGeneralized linear modelConfidence intervalsBinary outcomesGlobal functioningDuration of untreated psychosis groupSymptom severityUntreated psychosisSpecialty careCSC programsImpact of duration of untreated psychosisFunctional gainsModel repeated measuresMixed model repeated measuresOdds ratioNo significant differenceLogit link functionStatus improvementContinuous outcomesSocial functioningInsight and suicidality in first-episode psychosis: The mediating role of depression
Tayfur S, Song Z, Li F, Hazan H, Gibbs-Dean T, Purushothaman D, Karmani S, Terashima J, Tek C, Srihari V. Insight and suicidality in first-episode psychosis: The mediating role of depression. Schizophrenia Research 2025, 275: 189-195. PMID: 39754935, PMCID: PMC12317406, DOI: 10.1016/j.schres.2024.12.013.Peer-Reviewed Original ResearchConceptsFirst-episode psychosisPredictors of suicideCoordinated Specialty CareTreatment of depressionPersistence of depressionEffects of depressionSuicide attemptsMediation analysisPrevent SuicideDepressionSuicideImpact suicidePsychosisTargeted interventionsLongitudinal cohort studyEarly treatment stageParticipantsSignificant predictorsImproving clinical outcomesRegression analysisSpecialty careClinical outcomesCohort studyRelationshipMonths
2024
Baseline predictors associated with successful weight loss among breast cancer survivors in the Lifestyle, Exercise, and Nutrition (LEAN) study
Hoobler R, Puklin L, Harrigan M, Cartmel B, Li F, Sanft T, Ferrucci L, Irwin M, Playdon M. Baseline predictors associated with successful weight loss among breast cancer survivors in the Lifestyle, Exercise, and Nutrition (LEAN) study. Journal Of Cancer Survivorship 2024, 1-9. PMID: 39528779, DOI: 10.1007/s11764-024-01702-3.Peer-Reviewed Original ResearchBreast cancer survivorsClinically meaningful weight lossCancer survivorsWeight loss interventionCancer SurvivorsBreast cancer survivorsWeight loss successConclusionBreast cancer survivorsPrevention of weight gainAssociated with lower oddsHistory of weight gainHealthy body weightMultivariate logistic regressionCancer treatmentSuccessful weight lossBreast cancer treatmentIntervention armLower oddsResultsBaseline dataDesign of programsWeight lossLogistic regressionC-statisticWeight gainSurvivorsInterventionScreening, brief intervention, and referral to treatment for pain management for veterans separating from military service: study protocol of a hybrid type 2 study testing implementation facilitation versus training-as-usual
Sellinger J, Rosen M, Lazar C, Gilstad-Hayden K, Dziura J, Li F, Mattocks K, Weede A, Sullivan-Tibbs M, Rose L, Vassallo G, Manhapra A, Turner A, Vogt D, Woodward E, Hartmann C, Haskell S, Mohammad A, Martino S. Screening, brief intervention, and referral to treatment for pain management for veterans separating from military service: study protocol of a hybrid type 2 study testing implementation facilitation versus training-as-usual. Pain Medicine 2024, 25: s99-s106. PMID: 39514877, DOI: 10.1093/pm/pnae062.Peer-Reviewed Original ResearchConceptsTraining-as-usualImplementation facilitatorsReferral to treatmentCase managementBrief interventionHybrid type 2 effectiveness-implementation trialPain managementImplementation strategiesPrimary implementation outcomeSubstance misuseProportion of participantsPain careUsefulness of screeningVeteran engagementVA sitesImplementation outcomesPragmatic trialPain serviceVeteran participantsCase management systemPain intensityDischarged veteransStudy enrollmentVeteransChronic painThe anomalous effect of COVID-19 pandemic restrictions on the duration of untreated psychosis
Nicholls-Mindlin J, Hazan H, Zhou B, Li F, Ferrara M, Levine N, Riley S, Karmani S, Mathis W, Keshavan M, Srihari V. The anomalous effect of COVID-19 pandemic restrictions on the duration of untreated psychosis. BJPsych Open 2024, 10: e216. PMID: 39628123, PMCID: PMC11698182, DOI: 10.1192/bjo.2024.813.Peer-Reviewed Original ResearchPersistent and multiclonal malaria parasite dynamics despite extended artemether-lumefantrine treatment in children
Goodwin J, Kajubi R, Wang K, Li F, Wade M, Orukan F, Huang L, Whalen M, Aweeka F, Mwebaza N, Parikh S. Persistent and multiclonal malaria parasite dynamics despite extended artemether-lumefantrine treatment in children. Nature Communications 2024, 15: 3817. PMID: 38714692, PMCID: PMC11076639, DOI: 10.1038/s41467-024-48210-7.Peer-Reviewed Original ResearchConceptsDay 7 lumefantrine concentrationsArtemether-lumefantrine treatmentRing-stage parasitesEarly post-treatmentEarly post-treatment periodArtemether-lumefantrineArtemisinin resistanceDay regimenMulticlonal infectionsEfficacious therapyFollow-upRandomized trialsPersistent clonesTransmission settingsEffective treatmentPost-treatment periodRegimensAntimalarial studiesStandard diagnosticsStandard 3DaysPost-treatmentChildrenTreatmentTherapy
News
News
- August 07, 2023
New Yale Study Shows Aerobic Exercise Relieves Pain for Ovarian Cancer Survivors
- August 03, 2023
Lung Adenocarcinomas: New Findings About Resistance to Targeted Therapies
- February 15, 2023
Discoveries & Impact (February 2023)
- August 11, 2022
Discoveries & Impact (August 2022)
Get In Touch
Contacts
Academic Office Number
Locations
300 George Street
Academic Office
Ste Suite 511
New Haven, CT 06511