Evaluation of various mass spectrometry mode based on gas chromatography for quantifying the polycyclic aromatic hydrocarbon metabolites in human urine
Bao S, Qian J, Qiu T, Jiang W, Gu W, Qu Y, Bai X, Yu X, Jiang Y, Tang S, Lv Y, Shi X, Lu Y. Evaluation of various mass spectrometry mode based on gas chromatography for quantifying the polycyclic aromatic hydrocarbon metabolites in human urine. Journal Of Chromatography A 2024, 1739: 465521. PMID: 39566290, DOI: 10.1016/j.chroma.2024.465521.Peer-Reviewed Original ResearchElectron ionizationHuman urinePolycyclic aromatic hydrocarbonsGas chromatographyOH-PAHsHydroxylated polycyclic aromatic hydrocarbonsTandem mass spectrometryRange of compoundsMethod validation criteriaMass spectrometry technologyAromatic hydrocarbonsMass spectrometryHuman exposure to polycyclic aromatic hydrocarbonsExposure to polycyclic aromatic hydrocarbonsPolycyclic aromatic hydrocarbon metabolitesNational human biomonitoring programSample volumeHuman biomonitoring programsHuman biological monitoringIonizationBiomonitoring programsUrine samplesHydrocarbon metabolitesBiological monitoringMinute concentrationsDetermination of persistent organochlorine pollutants in human serum by combining liquid-liquid extraction and solid-phase extraction with gas chromatography-tandem mass spectrometry
Qiu T, Jiang W, Bao S, Qian J, Wang C, Tang S, Shi X, Lu Y. Determination of persistent organochlorine pollutants in human serum by combining liquid-liquid extraction and solid-phase extraction with gas chromatography-tandem mass spectrometry. Microchemical Journal 2024, 197: 109699. DOI: 10.1016/j.microc.2023.109699.Peer-Reviewed Original ResearchSolid-phase extractionGas chromatography-tandem mass spectrometryLiquid-liquid extractionPersistent organochlorine pollutantsChromatography-tandem mass spectrometryMatrix effectsTarget analytesMass spectrometryMultiple reaction monitoring (MRM) modeReaction monitoring modeMethod detection limitsOrganochlorine pollutantsElectron impactSample preparation procedureGC-MS/MSDifferent spike levelsHuman serumApplicable analytical methodsLimit of quantificationMethyl tert-butyl etherQuality control samplesMonitoring modeTert-butyl etherDetection limitPreparation procedure