2024
Leisure-time activities and disability among Chinese community-dwelling oldest old: evidence from the Chinese Longitudinal Healthy Longevity Study
Zhong W, Wang X, Liang F, Song W, Chen Z, Li Z, Shen Q, Shen D, Nan Y, Xiang J, Li C, Ye Z, Huang H, Wang J, Lv Y, Shi X, Mao C. Leisure-time activities and disability among Chinese community-dwelling oldest old: evidence from the Chinese Longitudinal Healthy Longevity Study. European Journal Of Public Health 2024, 34: ckae129. PMID: 39254527, PMCID: PMC11631485, DOI: 10.1093/eurpub/ckae129.Peer-Reviewed Original ResearchLeisure-time activitiesRisk of disabilityOlder adultsChinese Longitudinal Healthy Longevity StudyChinese Longitudinal Healthy Longevity SurveyActivities of daily livingChinese community-dwellingCox proportional hazards modelsPublic health problemLeisure-timeLongevity SurveyAcceleration of population agingCommunity-dwellingProportional hazards modelDaily livingPhysical performanceWatching TVHealth problemsFrequent engagementDaily activitiesAffecting disabilityDisabilityHazards modelPopulation agingLongevity Study
2023
Genetic associations with longevity are on average stronger in females than in males
Zeng Y, Chen H, Liu X, Song Z, Yao Y, Lei X, Lv X, Cheng L, Chen Z, Bai C, Yin Z, Lv Y, Lu J, Li J, Land K, Yashin A, O'Rand A, Sun L, Yang Z, Tao W, Gu J, Gottschalk W, Tan Q, Christensen K, Hesketh T, Tian X, Yang H, Egidi V, Caselli G, Robine J, Wang H, Shi X, Vaupel J, Lutz M, Nie C, Min J. Genetic associations with longevity are on average stronger in females than in males. Heliyon 2023, 10: e23691. PMID: 38192771, PMCID: PMC10772631, DOI: 10.1016/j.heliyon.2023.e23691.Peer-Reviewed Original ResearchGenome-wide complex trait analysisGenome-wide association study datasetGenetic associationSex-specific genetic variantsSex-specific genesGenetic variantsComplex trait analysisReplication analysisPolygenic risk score analysisIndividual genesGenetic datasetsCandidate genesBiological functionsTrait analysisRisk score analysisGenesMiddle-age controlsLongevityIndependent datasetsLongevity StudyUnderlying mechanismGWASFuture investigationsVariantsSNPs